973 Comments
Michel's avatar
James Miller's avatar

Great article. Very useful. Actually reading this is making me interested in returning to doing more research and observation on a surgical topic- the first time since I retired from surgery a few years ago— but I am now interested to watch wound healing / skin graft taking/ ulcer healing with DMSO help. That being said, since you introduced your last article I have been using it with neurologically damaged patients , chronic pain, and patients with autoimmune diseases and at very first response the responses have been very positive- in line with the data you present. As I have explained the data you introduced me to patients and given them the option they are showing intense interest. I am excited to follow these outcomes!

A Midwestern Doctor's avatar

A few of my colleagues who used DMSO for a long time found it was phenomenal for inflammatory bowel diseases. It's really a shame the surgical field never learned about UVBI or DMSO because it would significantly improve their outcomes and reduce their malpractice.

Fred's avatar

How is DMSO used when treating inflammatory bowel diseases? Topical or oral, et c?

A Midwestern Doctor's avatar

Normally topically, but will come in later part of the series.

ML's avatar

Really looking forward to this as I have inflammation, chronic constipation, “leaky gut,” and poor digestion! Thank you AMD!

pretty-red, old guy's avatar

me too.

I just bought some DMSO liquid but have yet to try it. . .

pretty-red, old guy's avatar

great looking forward to that!

I have SIBO, has improved a bit since taking your advice on improving "motility", so thanks! Ready for DMSO, doc!

TnDoc's avatar

Oral CBD (cannabidiol) in sufficient doses will help significantly with chronic inflammation (i.e., fibromyalgia), IBS, arthralgia/arthritis, etc.

pretty-red, old guy's avatar

thanks TnDoc.

Can you offer a link or a starting point for dose?

TnDoc's avatar

The problem with CBD is that it is unregulated (if less than 0.3% THC with it) - soooo... One needs to be careful about sources. More than 50% of random products bought in the greater Miami area during an investigation of CBD stores and smoke shops run by "Miami Herald" last year were contaminated with pesticides (very bad), heavy metals, and heaven only knows what else...

Wife and I take a 150mg gelcap from letitgrowhemp.com (Colorado) every AM - "full spectrum CBD". They are the only company I have found that makes this strong a cap (usually caps are in the 20-25mg range and one would need a handful to get the desired effect). I watch for their sales as it is not cheap. This company also makes good pet drops. We rescue cats and dogs and use them for pain and anxiety issues..

Other reliable sources are sunsoil.com (Vermont) and charlottesweb.com (Colorado- the original CBD company - pricier, but their gummies are good to use for young kids with seizure disorders, ASD, ADD, behavioral issues, etc.).

I have NO monetary or business relationship with any of these folks and this is not "medical advice".

Peace and hope!

Fain Zimmerman's avatar

Your link shows several products but all greater than 150mg. Which one have you found most effective?

TY!

TnDoc's avatar

The listing is confusing, but there are 4500mg in a bottle of 30 150mg full spectrum gelcaps OR 4500mg in a 30cc dropper bottle (150mg/1 cc dropper). We take one of the gelcaps every AM.

Fain Zimmerman's avatar

Where is the series? I'd like to read through all of it. Thank you!

Frank's avatar

Hi Doctor, can you tell me where I can get information on dosing DMSO? Thanks.

Laurie's avatar

At the end of every article. Externally I tend to use 33%

Michelle Goldstein, MSW's avatar

A close family member suffers with Crohn’s complications so am very interested in this topic

Mrs. Itoldya!'s avatar

My question too! I only purchased liquid & gel forms. As soon as it arrives, I’ll be taking my day 1 of 3, FenBen & Ivermectin, and tropical applying DMSO gel, to sore joints & on my tummy for large bowel issues. I have no idea what to expect, but do not worry about any harm.

Hubby is going to be taking the same, 3 day Fen & Iver, but he’s going to try DMSO on some of his psoriasis patches.. 😔🙏

A Midwestern Doctor's avatar

Psoriasis is one condition where DMSO sometimes makes worse rather than better.

Garhett Rittenhouse's avatar

Doc...will you include anything on external/internal hemorrhoids with the bowel diseases?

Thanks for these articles. I'll try UVI this Thursday because of your wonderful article.

Garhett Rittenhouse's avatar

Hi doc...TL:DR...DMSO worked/helped on two different extremely difficult issues (arthritis and hemorrhoids...tried on butt before I saw your link :-))). Read on...

Background:

1. I was diagnosed with Inflammatory polyarthritis (which I think is just a more exciting name for RA which moves all over my body) in 2011 (about 39 years old). Very strange...no joint damage...has required methotrexate, leflunomide (about four months ago), and prednisone (which I've been trying to ween off of for about a year or two...and...was down to 1 mg/day as of Sunday of last week).

2. As mentioned in the previous post...also battling hemorrhoids as I was taking a HIGH amount of prednisone (and cytoxan) at one point (due to Minimal Change Disease...which came about due to pneumonia vax...I think) and was a true pain in the ass :-).

Last week, I had a flare of arthritis through my left shoulder blade which impacts even taking a deep breathe (one of the reasons my wife thinks it cannot be arthritis) and couldn't sleep which usually starts flaring down to left wrist, then might switch to right wrist. Typically, I would bump prednisone backup to 10-15mg and start to try to ween again.

I purchased DMSO the week before...just in case of a flare up so I was "in luck"....I started applying it to my back multiple times per day with 1 tsp of DMSO (99.9%) (seems to be about 1 gr) with 1 tsp of distilled water...mixing a batch each time. Day 1...slight reduction in pain but allowed me to sleep....Day 2...applied probably every hour or two...MUCH reduced pain...Day 3...pain was gone. It allowed me to finally remove the last of prednisone by Wed... which I normally bump when I get a flare just so I can sleep. Unbelievable!!!!

With such success...I thought...well...I will take the cotton pad I used to swab on back on Day 3...cover in Castor Oil and sit on it between the cheeks. The next day...my two external hemorrhoids seemed to disappear...much smaller than in the past (and the small internal ones the doc did not "tie" off as they were too small) also seemed to be gone. Wow!!!!

SMALL side effect: lots of itching on my back and slight garlic breathe at night Day 2.

BIG side effect: when I put it on my butt...after having a "lot" on my back...caused malaise...stomach upset/nausea...much stronger "odd" taste in my mouth...I awoke in the middle of the night in sweat and paranoid my own poop was flowing through my blood and poisoned me :-)) I recovered after a couple days of not using it and still felt great. I tried again on butt this week...just to make sure this week...only a slight tummy upset...like Preparation H suppository but the pain from hemorrhoids is almost completely gone. AMAZING again.

I can't thank you enough doc. I don't have a large network but shared it with a lady at work who is suffering from back pain (and another guy who had spine fusion). Next time, I'll tell you about my UVI :-)))

Thanks again doc!

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A Midwestern Doctor's avatar

Ah wonderful! Someone else replied to that comment and also had success with a hemorrhoid. Can I copy your comment into that thread?

Garhett Rittenhouse's avatar

Sorry for my delay doc...yes...please!

Dennis N's avatar

Garhett...I dont know where you live but if you are in the states there are chiropractors and naturopaths that do an electric (negative galvanic) treatment on the hemmorrhoids that works amazingly well! I have had it done twice with great success. Its called Keesey treatment if you want to search...there are a few chiropractors in Portland, Oregon that do the treatment. a few in other states as well

Bambi_Ann's avatar

Thank you Garhett. I have been applying DMSO (80% diluted) to my ,om's back but I first either rub in castor oil or Arnica and then I put the DMSO on it. But we do it once a day and it has not helped. Did you do it several times from first day on? Also it seems you diluted to 50% and used directly on your back right?

Thanks

Garhett Rittenhouse's avatar

Hi Bambi_Ann…I’m sorry to hear about your mom. Yes to both. I applied directly to my back. And I used a 50-50 solution BUT with “distilled” water when rubbing on my back. I did not dilute with Castor Oil on my back (only on my butt as I was worried about itching and oil helped “hold” in place…sorry to be gross). On your mom’s back…it will be wet and drip down…make sure she wears cotton and maybe tucks a towel into her waist band until it dries…I was wearing nylon shorts and it stuck to me…not good…maybe unhealthy and irritated when pealed off. Midwestern Doc suggested you apply while she lays on her stomach to use gravity. It is going to itch…a lot! I did it often thru the day the second day. By third I felt a ton better.

Finally, I started drinking about 3g per day about few days ago (Doc also provided a formula but said we could start with 3g…it’s about 1.5 tsp in 12 oz of water)..,and…I feel good.

I stink bad …I’m the anti Dracula….fitting for this time of year :-)).

Sorry for my delay (I’m new to Substack) and to go so long. Good luck to your mom (and you). I’ll keep an eye if u have more questions.

Bambi_Ann's avatar

Hi Garhett,

Thanks so much. You were not late at all. Don't think I will give it to her by mouth. She drinks alcohol everyday and I have read that it's not a good idea to combine both.

Mkalves's avatar

Oh boy. I have psoriasis and Psoriatic arthritis. I stopped cosentyx 3 months ago and now my wrist is off the charts in pain again. So I purchased DMSO from the DMSO Store and have been applying it to the wrist for two weeks and no improvement. So does DMSO make Psoriatic Arthritis worse too?

Marcia K.'s avatar

AMD commented to a prior reader that DMSO can sometimes make psoriasis worse for many.

Zade's avatar

I'm so glad AMD is honest and is clearly not touting a "wonder drug" here.

A Midwestern Doctor's avatar

I am not selling DMSO so I have no reason to lie about it!

Zade's avatar

Two days ago I used it on my neck and lower back. For me it turns out indeed to be a wonder drug. If I hadn't tried it I wouldn't have believed the nearly instantaneous reduction in pain from pinched nerves at both sites. And the relief is persistent! I tend to have every side effect possible to every med but so far, no bad effects. Thank you, from the bottom of my heart, for your articles on this "solvent"!

Melinda's avatar

It works 100% on my psoriasis patches!

I've been using a 40% DMSO mixed with black seed oil as a carrier oil. It permanently cleared up the patch on my forehead and eyelid (ouch!) and I have to apply it once every 2 weeks minimum to keep my scalp patch from getting flaky. I'm going to also start taking it also orally so hopefully it clears it all up from the inside.

Jason Brain's avatar

Have you found any information on oral dosage suggestions? This is all I've seen:

“The usual oral dose of DMSO is one teaspoon per day of DMSO 70% (Morton, 1993). Oral DMSO is normally mixed with Tomato juice or Grape…”

From: https://www.scribd.com/document/672975025/DMSO-Use-Protocols

Also, “1 teaspoon in 5 ounces of water or juice.” is another oral dosage suggestion from the book "Healing with DMSO" which doesn't mention anything else about dosage sadly.

Melinda's avatar

I read the same book, and I mix the 1 tsp with 12 oz water since I'm on a keto diet and didn't want the added sugar of juice. It doesn't taste great... but it has also cleared up a tooth infection by swishing it around my mouth before swallowing :))

I have been a little hesitant to use it daily orally until I find out what my crowns are made of and if the DMSO will dissolve them, so I put off drinking it daily until I consult my dentist next month.

Jason Brain's avatar

Thanks for the tip Melinda, and your hesitation about potentially dissolving crowns is duly noted too – I had not considered that and will let others know in my family in case they have crowns.

Melinda's avatar

My dentist gave the all-clear on drinking DMSO, said there are no plastic parts in dental work! So I’m going to be using it as a mouthwash and drinking it (diluted) more regularly. Just thought you might like to know!

pretty-red, old guy's avatar

UV light, you surely must already know though, does wonders for Psoriasis as I recall my dad using a sunlamp.

JosieC's avatar

Yes, it does. I was frantic to find something that would help. I bought a UV light (with built in timer) meant for such skin treatment (though expensive). It was the ONLY thing that helped, actually entirely cleared it up, so it was well worth the cost.

Thinking Mama Bear's avatar

Can you give me a sample if what you use for UV light? Which is better UV or infrared light for psoriasis?

yantra's avatar

good point, i will tell an afflicted friend

Deb wis's avatar

Hubby and I are on a 3 day out of 7 fenben detox too. The parasites we visabley expell are shocking…. We have rotated between fenben and ivermectin. 8weeks of each at a time.

Looking forward to adding DMSO for knee pain.

Fred's avatar

Really? Is there any obvious explanation why you have (had) parasites in your guts? Pets?

Deb wis's avatar

It’s suggested that we all have parasites ….once I started detoxing them, it was visibly obvious. Other countries “de-worm” their school aged kids . Not US.

Deb wis's avatar

Themedicalrebel.com I follow this Doc too. I have come to understand everyone has parasites.

Mrs. Itoldya!'s avatar

Some Docs have suggested we all do, all the time. Levels & balance against gut bacteria is unstudied. Parasites can come from a host of environmental exposures, lake water, well water, contaminated food, mattresses, there’s a very long list. And yes, animals.

yantra's avatar

like letting dogs lick your childs face and mouth

Crispyb's avatar

I would also like to know this

Bambi_Ann's avatar

how much of each do you take? Is there a source where you got this protocol?

Deb wis's avatar

It’s animal dewormer ..weight dependent so dose yourself like a horse

Fain Zimmerman's avatar

Let us know how well that works for you both. TY

JosieC's avatar

That ivermectin is very expensive, as it is from all the sources in the U.S. that I've seen. It SHOULD be inexpensive; it's a generic drug. But all these U.S. pharmacies that sell it seem to be taking advantage of its post-Covid popularity. I order it from India (All Day Chemist) , a reputable pharmacy from which I've also gotten hydroxychloroquine and LDN. FAR less expensive.

Thinking Mama Bear's avatar

Not possible in Canada. The same border czars that let in Fentanyl - confiscates IVM.

272 @yahoo.com's avatar

I can't thank you enough for this info!

Chelles's avatar

So sorry to comment on a thread, but there’s some glitch with substack and my (very old phone/computer) that only lets me comment on other comments 😅

Reading the parts in this series about recovering tissues (sprains), rearranging proteins, and how it helps other musculoskeletal issues has me wondering about its potential with EDS patients? Have you come across anything that might support this?

yantra's avatar

good question - i was wondering when i read what MWD wrote: "DMSO is often used to treat scars. This may be in part due to DMSO being observed to disrupt the links between collagen fibers" - if that would mean it could accelerate or increase the ligamentous laxity. I am going to post your Q and my comment as a new post so it will more likely be seen.

A Midwestern Doctor's avatar

I don't the data to give a good answer to this question

yantra's avatar

you are quick! and i can see i didn't need to repost it after all.

Chelles's avatar

Thanks for your attempt Yantra, and your response, AMD! The article on the musculoskeletical implications and DMSO’s use in autoimmune conditions only furthered my curiosity - particularly with its collagen connection, since EDS is a genetic (?) collagen deficiency issue. I question the genetic component because I’m been increasingly wondering about vaccine damage disrupting normal collagen development/production/absorption/wathaveyou and that having epigenetic consequences for the offspring specifically. :)

yantra's avatar

chelles - i think, at least in one case i know of, covid itself (whatever it actually is) may have disrupted collagen production. The person was not covid-vaxxed, but had had plenty of childhood vaccines years ago.

J Pattison's avatar

Question: My brother has terrible cancer pain. He's on narcotics to ease the pain, but it causes terrible insomnia for him. He wants to try DMSO immediately. Would he need to be off the narcotics for a full 5 days (the time for it to be out of his system) before trying DMSO? I just don't want the narcotics to be intensified in his system. Seems like that could be dangerous. How long do you think he should wait after taking the narcotics?

Lps's avatar

Different problem, but same question. Hope he sees this.

J Pattison's avatar

What is your question? I can probably help.

J Pattison's avatar

I know so much more since I asked those questions. What is your question? I can probably help.

Lps's avatar

Sorry, this is so late. I have a hard time navigating this site (newbie here).

My spouse is on opiates and pregabalin for back pain. He has ‘failed back syndrome’ from so many back surgeries. The last (2008) being a nine hour surgery with 9 vertebra fused (S1-T10) w/ three cages. They went in from both the front and back, all this in one surgery. Two+ pounds of titanium and surgical stainless steel metal in his back. He almost died from blood loss. Recovery took over a year. It was horrific. And frankly, has ruined his life.

Doctors today have called his surgery ‘barbaric.’ And if we knew then what we know now, we would have never done it. So…he’s in constant pain. And spends most his time flat on his back.

We are desperate for some help. In reading these articles…we are worried about the ‘potentiate’ of the opiates into his system (not that he’s taking/allowed enough to help his pain levels much). We also read that the pregabalin is bad ju-jus when combined with DMSO.

We are reading everything we can on the subject but can find **NO** dosing recommendations or how to start DMSO for those on opiates.

Should he stop the meds? Cut his doses in half? Topical for neuropathy? Internal for nerve pain and scar tissue? Does external use ‘potentiate’ medications or just internal use? Is the metal in his back safe to use w/ DMSO?

We are trying, hoping AMWD would take us (him) on as a patient. We were also hoping to get the IV or injections (?) under a doctors supervision. Alas, other than commenting on here, I haven’t found a way to contact AMWD. Nor have my pleas on here been answered. 😔

So, thank you so much for your response. (We did buy the DMSO in an aloe base roll-on but have been too scared to use it.) Any help would be appreciated. 🤗

Blessing to you…

J Pattison's avatar

Just seeing this now. I’m off to church, and then I have company this afternoon, but I would love to connect with you. Maybe talking on the phone would be easier. Here is my email address: mjpattison@mi.rr.com. We’ll start there and hopefully connect by phone this week. Jennifer

Lps's avatar

Off to church myself. Will contact you. Thank you!

Fain Zimmerman's avatar

Is there a good book or other source that explains how best to use it? I have some tendonitis in my lower arm, elbow area - pain in the middle area between the two bones. What is the best way to apply the DMSO - a topical get (I have one with water and 1 with aloe) or to drink some? I have a 99% liquid. I'd love to find better guidance. Thank you!

Lps's avatar

Do you still accept patients? I am looking for help for my husband.

MNI7's avatar

Thank you so much for all the time and effort that go into your posts. The level of information you share is staggering, I can’t even imagine how many days/hours go into each one. And the info you’re bringing to the masses is astounding! Life-changing and life-saving even. You are a light and a blessing - wishing you endless blessing in return 🙏🏻♥️

A Midwestern Doctor's avatar

Thank you for noticing! It's actually quite fun to track these studies down. But that said, this one definitely took a toll on me to write.

Ruth Lock's avatar

I feel like the 7 year old me waiting for the rural Bookmobile library bus, I so love to read and learn. This has me as excited at 65 yrs as I was at 7! Ya done good Doc.

A Midwestern Doctor's avatar

I still find all of this very exciting too!

Julie's avatar

Hello, Doc! Who are you and where do you practice? Where can I get some DMSO? Thank you!

Miss Rodeo's avatar

Exactly! I remember standing in front of the ranch house, jumping up and down when the Bookmobile arrived. Hadn’t thought of this analogy, but it fits perfectly.

sadie's avatar

Yes! We had one come to our one room school house... fun times!

RU Pondering's avatar

I really admire your work AMD! I hope that one day we live in a culture where heroes like yourself can share information with out masks or fear of being criminalized, de-platformed or de-licensed. Since your first post on DMSO, I have spent a great deal of time researching the subject and have a few anecdotes to report.

I have had a large lipoma (fatty tumor) on my arm for many years. It was about 50cm in size (or about the diameter of an egg for your American audience). I used a topical application of 50% DMSO plus curcumin & ginger. I have been applying the DMSO to the lipoma 2-3x a day for less than a week and the tumor has already shrunk to 12cm (the size of a blueberry).

My wife has had pretty severe knee pain since injuring it 15 months ago. After explaining to her what DMSO was, I applied the same DMSO+curcumin mixture to both sides of her knee. She reported that it relieved her pain even before I finished massaging it in. The following day I asked if gave her a few hours of relief. To which she said, "no". I was a little disappointed, until she smirked back "it wasn't a couple of hours, it hasn't hurt since".

Be warned, the curcumin stains your skin orange for a day. If you apply it at bed time, it will be less noticeable by morning. But if you live in a "blue" area, it might trigger some TDS.

A Midwestern Doctor's avatar

Isn't it unbelievable something like that has been kept from us for decades?

RU Pondering's avatar

You misspelled "criminal". I was pondering the other day that perhaps by introducing social security, we instead incentivized our government to act in ways that shorten our life spans. From fluoridating our water, poisoning us with pesticides and playing it off as a vaccine miracle (polio), subsidizing bad agriculture practices, and promoting dangerous but expensive "cures" while suppressing real ones; it all seems to have started shortly after it was in the government's best interest for us to live only long enough to retire.

A Midwestern Doctor's avatar

A lot of people thought that was a motivation behind COVID since the virus disproportionately targeted the elderly and was not managed well for them.

yantra's avatar

i remember early on some young people online (gleefully it seemed) referring to it as "boomer remover".

Lisa Beth W.'s avatar

So disgusting and inhuman. Devilish.

Ben's avatar

What do you do about water fluoridation? I’m just starting to look into options for getting non-flouridated water.

Ben's avatar

What was the justification used for the FDA to ban it? I didn’t see much discussion of that in the article (maybe I missed it).

RU Pondering's avatar

Dang it! I should have just stuck to egg and blueberry. The units should be mm not cm.

RU Pondering's avatar

I make 40ml at a time for a dropper bottle. I like to make a light gel, just enough xanthum gum that it doesn’t run. I mix larger batches of xanthum gum and distilled water separately. (To gel properly it needs to be boiled and you don’t want the heat breaking down the DMSO or curcumin.) I create a 50:50 mixture of gel (or distilled water) and DMSO. The DMSO will thin the gel. Then I add 2000-3000mg of curcumin. If you are fair skinned and you plan on using it anywhere it will be visible, I’d use less, like 500mg. I like to use pure curcumin powder because the capsules have fillers. But if you already have curcumin capsules and it doesn’t have too much other junk, you can use that. It really does stain, so start out light with the curcumin. You can always add more.

OneDayAtATime's avatar

What form is the curcumin and ginger in that you add to the DMSO?

RU Pondering's avatar

Powdered. Just open a supplement capsule or two and pour it in to the DMSO mixture. Curcumin has profound effects even though it is very poorly absorbed. AMD just circumvented the poorly absorbed issue.

Dawn's avatar

Hi RU Pondering, just wanted to say thank you for posting the info about curcumin. I have a knee injury from October that often gets stiff and affects my gait (which probably doesn’t help the neck and back!) I applied the DMSO/curcumin about 4 days ago and I’m still pain/stiffness free in my knee. Great info! Also glad to hear you and your wife are doing better.

beth02's avatar

Hi, can you provide "recipe" for this mixture ? How much DSMO ? what type of Circumin or Tumeric ? Thanks !

E.Y.'s avatar

Thank you so much !! I have grade 4 chondromalacia and basically no cartiladge left behind the kneecaps , due to a patellofemoral tracking disorder . I strained my knee several days ago and the swelling was significant . I thought I would have to have the fluid drained and steroid instilled . I have had this done twice in the past . I used castor oil first on my knee , rubbed it in , then , 100% DMSO . I iced and rested the knee . I did this two or three times a day . Amazing response !! Better than draining and steroid !! I put some DMSO on my dog’s paraspinal muscles . She has lumbar spondylitis . She was moving better and brought me a pine cone to thank me !!

Chelles's avatar

I apologize for commenting on a sub-comment, but it’s the only way I can comment on substacks. I’m not sure why, but I’m unable to access anything on my desktop, and it’s all glitchy on my phone. Anyway...

These recent articles have fascinated me, so much so, that after two years or so of reading and sharing your articles I’ve finally become a paid subscriber. Worth it.

What I want is....just help. I’ve spent years, thousands and thousands of dollars, and so much time trying to help my daughter - in the meantime I’ve become so exhausted I can barely care for myself. I feel paralyzed about trying anything else to help her - not mention that in our case everything results in a fight with her. Our dr just retired, so I’m feeling left in the lurch, in addition to feeling like I have no one to trust (he is a brilliant/awake dr, much like you!).

I could tell our life story, which isn’t as bad as it could be, but still, it’s out of the ordinary. We have no diagnoses really except constant UTIs, possible brain damage from birth compaction, and selective mutism (though she used to talk more). Recently my daughter completely collapsed in public and I’d thought she’d died, with empty eyes and blue lips. But it was ruled a side effect of yet another uncontrolled UTI, and I’m left with the utter exhaustion that all the work, time, money, and energy of our past 6 years hasn’t gotten us anywhere. She’s only 14. I only just weaned her off needing me to take her to the bathroom. It’s still a daily fight.

On top of it I’ve been in chronic pain for a decade, sprained my neck last year which won’t quite heal...these last two posts gave me some hope that maybe there’s something beyond the PT and Chiropractic (I’m pretty much against most pharmaceuticals for non-emergency uses)... and I’m fine experimenting on myself, but less so on my daughter. I feel like I read all these wonderful transformative stories of children and yet it’s always out of reach for us....I’d just love help...some hope...some other new path for her...so many people around me keep having dreams that she’s suddenly talking to them, and, being the sensitive person I am (oh how many of your posts have resonated with me and my physique!!), I can’t take those lightly. I’ve had themself, when I haven’t even dared to hope she’d talk again outside the family...yet it’s like I’m being dared to hope!

Mary L.'s avatar

God bless you and give you hope, strength and the healing power of Jesus. May you find the path to everything you need DMSO, CDS, etc. to bring complete health for you and your daughter!

Auntie Claus's avatar

Chelles - so sorry for all you and your daughter are suffering. As mentioned by another commenter: seek first Jesus Christ and His wise counsel, through reading and studying the Bible. He speaks directly to each of His followers with His Word … I know from experience!

I have also suffered from frequent UTI’s and know the hazards and pitfalls of an endless succession of antibiotics. There are 3 non-antibiotic ways to successfully treat UTI’s that I can recommend to you (prevention through regularly taking one of these works the best … maybe 1x/week … you can figure out what frequency works for your daughter).

(1) Methylene Blue (research Dr. Francisco Gonzalez-Lima’s amazing work) - was the standard OTC treatment for UTI’s up until the mid-1960’s, when antibiotics were introduced. This is my favorite, because it actually kills the bacteria in the bladder and I don’t have any side-effects from it (other than bright blue urine!). You can buy USP-grade liquid from Amazon, but it tastes nasty and can stain things if you aren’t careful. My doctor had 15mg capsules prepared for me at a compounding pharmacy which makes it easy-peasy.

(2) Nasturtium-Horseradish capsules from Sanct-Bernhard.com in Germany. These OTC capsules have been available for 20 years in Europe. Studies show they are as effective as antibiotics. These are also very efficacious and easy on my system. You take 3 at a time, though, and it can be a lot to swallow. 😜

(3) D-Mannose powder is available from Amazon and very inexpensive. You put a heaping teaspoon in a 1/2 cup water and it is effective against E. Coli bacteria only. Check out the website “stoputiforever.com” for great, comprehensive information. This is my least favorite, because it makes my stomach hurt when I take it.

Caution: only do one of the above at a time … I tried 2 simultaneously a few years ago and I got terrible stomach cramps.

I hope one of these might help. God bless you!

Anne in NY's avatar

I would constantly get UTIs and put on every type of antibiotic without any relief. I finally tried Cranberry pills and found relief. I have since shared this info with many friends and family members who have also found the cranberry pills work better than any antibiotic. the key is to take 6 or more and wait a hour or two and then take more. I got relief in the first few hours. many friends have told me that I saved their lives with recommending these pills. Keep taking two or more for the day and following days. I keep bottles of these pills in every travel bag and never go anywhere without them. My daughter does the same. Here is the link on Amazon for the ones I use. HTH. https://www.amazon.com/Natures-Bounty-Cranberry-Supplement-Supports/dp/B002Y27JRE/ref=sr_1_1_sspa?crid=270N1X6ZGCLAV&dib=eyJ2IjoiMSJ9.kn1SlcZmVnMUKJLfya8zxvcW4bj5aoLBgeyibEFFO_NXqBTEVJ_RD2h4vxydJNl_7oFjMDrmiJpun9gK-4b_dZTBVOt3JwiRGHxxDIpJbWQZT5ukQn3IEdgNHto_xESbKXGYAhWC5sEBFbmgSzSYiaNsp24whueHaOy_xjfX1uux2340RgZp_R5romBqzYlNtOGr8kEIBsYqW_ohwsDFZCdYQcBeE231qCDQjNu0HZxCXsl_gmUwiV62IBGtsw_QrTHjyVB1JLZ_Q6JLpJ7MT8eezmk1VwOHie0BeDp7oqs.2svgtKnmSaLiX10kehXgVBm60RVvvkqUdJbb2nI9lEY&dib_tag=se&keywords=cranberry+pills&qid=1730138342&rdc=1&sprefix=cranbe%2Caps%2C177&sr=8-1-spons&sp_csd=d2lkZ2V0TmFtZT1zcF9hdGY&psc=1

Chelles's avatar

Thank you! Yes- so a big part of our issue with her mutism is an inability to swallow pills, and, quite frankly, she shuts down in all manner of ways when something is required of her, thereby putting all the emotional and physical work on me to maintain it all. And I am so wearied by doing this for so long, it’s almost like a PTSD response to supplements for her! And that’s why it’s taken me this long to even respond - I had to work through some things to even read the recommendations (and I am not the kind of person who usually does that. Sigh). thanks again! We did Uquora for a while with her...

Rosie Langridge's avatar

Pure cranberry juice is very good for UTI. Better still is pure pomegranate juice. Both available from Biona.

Old_Mainer's avatar

Chelles, have you explored methylene blue for UTI? It is an approved treatment for UTI short term and there is extensive unapproved use long term for mitochondrial health. I suggest exploring as a UTI preventative.

Chelles's avatar

No, but I will! Thank you!

Garhett Rittenhouse's avatar

Chelles, the midwestern doc wrote another article about ultraviolet light therapy (UVBI/UVI) https://www.midwesterndoctor.com/p/the-century-of-evidence-putting-light.

I am going Thursday for my first attempt with it. Hopefully, it will gain some improvement with my RA. I'm currently taking three meds which address symptoms but I want to see if my blood work improves.

All that to say...midwestern doc said UVI is a miracle therapy when it comes to chronic infections. I'd read the article. It may help address your daughter's UTIs.

Best of luck to you.

Chelles's avatar

Thank you - I will look at that!

SG_observer's avatar

Hello, this is a very late comment, but hopefully it'll trigger an email to you. A friend here tends to have UTI, and what do you know, VIM (ivm) cures UTI's... without the antibiotic side effects etc. Her recent cases of UTI's seem to have required higher doses of VIM though, but she doesn't get it as often as she used to anyways. Just an anec-data for you.

Kass Jackman's avatar

A female urologist, Dr. Kelly Casperson, strongly recommends as do many other physicians, Vaginal Estrogen for UTI prevention. It is not systemic. It just treats the area down there.

David Kukkee's avatar

DMSO is incredible. I suffered two weeks in bed with a back injury...and rose up and walked two hours after applying DMSO. I also have used DMSO many times to treat serious burns...every one of them healed quickly, and with significantly reduced pain. I crushed the cartilage in my right ear by accident, applied DMSO, and the wound was healed in three days, without scars. I have experienced no side effects other than the characteristic odor after use. It should be in widespread use.

A Midwestern Doctor's avatar

Can I add your comment to the article? Hopefully you can appreciate why this topic has bothered me so deeply for such a long time.....

David Kukkee's avatar

Thank you, A Midwestern Doctor, I do appreciate the fact that this issue has bothered you for such a long time...(I reside in the same camp as you find yourself)...and am grateful to you for publishing your report...our people have been defrauded out of a perfectly sound and useful substance that reduces losses, pain and death...safely. I am honored to say yes, please do add my comment to your article. I would like to see your article published on the front page of everything, consecutively, for 104 weeks, or until the pharmas collapse in shame, ignominy and bankruptcy. Thanks for all you do.

SC's avatar

Glad to hear you are better! I need some hope after feeling trapped in my disabled body from a lumbar herniated disc. It started 6 months ago and progressively got worse because the chiro made it worse, and I didnt know it was herniated.

I received a roll on 70% dmso three days ago, I think its helping very slowly bc I notice I can now stand a little longer than before. Im sure the roll on is fine. But, how often can I use it? I am currently having my husband roll it on my lower back 2-3x a day.

David Kukkee's avatar

Hi Sibel, sorry to learn of your herniated lumbar disc. Please understand that I am not a doctor, and therefore cannot give you advice...I can only tell you what I did, or what others did that I know of. Persistent back pain radiating down the legs is often a sign of a herniated disc, and requires imaging to confirm. A Chiropractor would ordinarily order X-rays, at least, to rule out a disc bulge, before proceeding with extensive manipulation, which could indeed , exacerbate the problem, i.e. causing increased inflammation, and swelling, furthering the compression on nerves in the foraminal path, resulting in pain and disability. DMSO is useful in reducing the inflammation and pain. I have used DMSO for many years, for a variety of issues, and have used it three times per day without any negative side effects.

It is my understanding that in severe cases, a discectomy may be required. In milder cases, often rest and gentle exercise, with DMSO will resolve, slowly. Nutrition plays a significant role in healing, as does the judicious use of applied heat or cold, as necessary. It is important to understand when heat or cold should be used...and not apply heat or cold at the wrong stage. Physiotherapists are often capable of knowing these details.

Frequently, a subluxation of the sacroiliac joints are the root cause of pain in the lower back, which is often resolved by manipulation of those joints by a Chiropractor...however, not all Chiropractors are totally efficient on this task, as is my experience. Some are better than others in performing the necessary adjustments, and some just don't accomplish the task. I would not continue with a Chiropractor whose work results in worsening condition. A disc bulge cannot be fixed with Chiropractic manipulation as far as I know.

It is my belief that gentle exercise, like walking, when tolerated, is very helpful in healing, as well as anything that improves circulation of oxygenated blood. DMSO application helps to alleviate pain and swelling, and improves circulation, from my experience. It is also my experience that sitting, especially for long periods, is not helpful.

If pain is unbearable and prolonged, medical doctors can prescribe anti inflammatory drugs like indomethecine, muscle relaxant medicine such as cyclobenzaprine, or other NSAIDS such as NAPROXEN, for short term pain relief, helping the healing cycle to progress. I do not use any of these drugs for extended periods because they can be harmful.

DMSO, in my experience, can help these medications to be more effective, thereby reducing the time needed for their use, reducing pain, as well as speeding the healing of injured tissue.

I hope this information is helpful Sibel, and that you heal up soon.

Timea Biro's avatar

Doctor, you are a treasure for humankind!

Words cannot express enough gratitude how I feel about the amazing work you do for us.

klimer's avatar

Applying topical 70% DMSO/30% Aloe Vera is one of the things my wife has tried to improve an old disc injury from a rough sky diving landing 50 years ago. Our functional med doc was very skeptical that anything could help her. But we threw everything at it, as failing to find a solution would mean intractable pain and loss of mobility and quality of life - there was literally nothing to lose. We had also heard that Urolithin A was potentially needed to resolve a possible spinal Cell Danger Response, so she has taken that as well. Additionally, I believe she had prolozone injections from our doc.

Our doc now thinks that the disc is healing, despite his initial heavy skepticism. After reading your article, I'm inclined to think it is mainly the DMSO that has been doing the magic. She now has very little pain from the disc, and she has less need to limit her physical activities in fear of worsening the disc damage. Our hope is that she will continue along a path of improvement over time. At there very least, she is no longer in fear that her days of mobility are nearing an end. She is greatful things have improved as much as they have, and is hopefully that more improvement is possible.

Recently, we've embraced the "Provident living" philosophy advocated by the Mormon Church (which most people would call prepping). We have in our hoard of medical supplies our DMSO/Aloe cream and some 99+% liquid DMSO. Iodine, Vitamin C, hydrogen peroxide, chlorine dioxide, fish oil, a digestive supplement and a nitric oxide supplement are also part of our essential therapies. Our goal is to have at least a year's supply on hand, especially in light of the repeated attempts (all failed, so far) that have been made by the pharmaceutical industry to attempt to control access to supplements.

Bless you for everything you do to help your fellow humans. Yours will be viewed as a life very well lived. I hope you inspire more of your colleagues to look outside the box that their training has put them in. If enough do, there's certainly plenty of hope for the future.

erin's avatar

What is a nitric oxide supplement?

klimer's avatar

The one I have used since May is Cardio Miracle. It's incredible for anyone who has suffered cardiac issues. It contains the Sinatra Solution for reversing heart failure. It has greatly improved my ability to tolerate heat during exercise. Basically, NO dilates blood vessels, allowing blood and nutrients to reach individual cells. Once you realize how capillary-dense your organs are, it is easy to understand how important individual cell nutrition can be (think about all the sqawk about mitochondrial dysfunction). My opthalmologist thinks it's great, and that it increases the odds that the AMD supplement that she recommends can actually get nutrients where they are needed. I apply DMSO to my temples in the hope that it can break up any agglutinated blood that could be blocking blood flow to my macula.

yantra's avatar

Some people have recommended first applying castor oil followed by a careful application of a little DMSO to the eyelids before sleep to help resolve eye problems like macular degeneration and detached retina. However, i do not know if it is entirely safe to apply dmso to the eyelids, or to use dmso on an ongoing basis.

klimer's avatar

Thanks for sharing. It would be useful to know why they believe castor oil would have a benefit.

yantra's avatar

well, from what i understand, castor oil all by itself is an amazing healing substance for many problems, and so some people use DMSO to drive the castor oil into bodily tissues, including the eyes. However, i do not know if it is entirely safe to apply dmso to the eyelids, or to use dmso in any application on an ongoing basis.

klimer's avatar

Yeah, I've used it before myself, though not with DMSO. There are several castor oil "bibles" in print, and none are all that highly rated. There must be some source of quality information about it. I remember cartoons where kids were forced to take castor oil. I'm sure there is a benefit and would like to know what it is.

Shirley's avatar

Yep. I was one of those. Hated it! No idea what it was supposed to do for us!

erin's avatar

Thank you! I looked it up on amazon but the ingredients don't mention nitric oxide. So I am confused.

klimer's avatar

The ingredients stimulate NO production. What is sold on Amazon is old stock. Check out cardiomiracle.com.

Seeking Clarity's avatar

I second the recommendation on Cardio Miracle. Great product

edservice's avatar

I’ve been reading your Substack in a Free subscription for a few months. I read your first article on DMSO in its entirety and with today’s second article, I signed up for an annual subscription and ordered a bottle from Amazon. It will arrive in a day or two. Can wait to try it on my foot, leg and finger neuropathy I’ve been dealing with for three years. The mild pain and problems with balance and walking I have ruined my golf game. I just can’t play anymore. After testing for a reaction , and barring any poor skin reaction, I will be painting them with DMSO. I’ve also lost the love of my life (wife) to dementia which I strongly believe may have been caused by using a prescribed STATIN drug for five years. I will be trying to get more information about how and where to apply the DMSO for her.

Thank you for your work. I will ask you to send these articles to RFK, Jr. as he’s been screaming about the FDA corruption for years.

Garhett Rittenhouse's avatar

Did you see MWD's article on statins? He talks about how people lose their mind on them. Yikes...sorry for your wife.

Angela Luce's avatar

Thank you so much for taking your time and energy to write this. My husband was out of work for 4 weeks with severe sciatica, and had suffered with the pain for a couple of weeks before he could no longer endure working. Just about 48 hours ago, after seeing this article, I bought some DMSO at the feed store and started putting it on him on Saturday afternoon, every 4 hours. Again on Sunday, and then today on Monday he is back at work. I cannot thank you enough!

Auntie Claus's avatar

P.S. My Dad told us of an adverse event related to DMSO use during his working career: lab technicians liberally used DMSO’s excellent solvent characteristics to clean glassware. One technician was a heavy smoker and immersed a hand in DMSO. Almost immediately he had a severe reaction and was rushed to the hospital where he almost died. He was found to have severe nicotine poisoning … the DMSO transmitted the nicotine stains from his fingers directly into his bloodstream.

Featherjourney's avatar

Interesting. I wonder if it was actually the nicotine or the thousand chemicals the cig companies used to (maybe still do?) put into cigarettes…for example, you could light a cig then set in in the ashtray and it would just keep burning. The nicotine in tobacco is a natural product but add hundreds or a thousand chemicals to it and it is no long “natural”. Just a thought

Elizabeth Parker's avatar

Even natural, I believe you can over do it. Nicotine is actually found in many of the foods we eat daily. The toxins in tobacco 'products' are what is addictive, not the nicotine.

Irunthis1's avatar

😯. Oh wow. Good note. Shows just how important washing the hands is in this.

Satan's Doorknob's avatar

Well yes and no. Many oily materials are difficult to remove with even soap and warm water. Anyone who's ever smoked (guilty as charged) or even just tried to clean dirty ashtrays, etc. knows that gunk is not going to be removed without a fight. The poisoning anecdote could well be true; regardless, it provides an excellent example of why your hands or other contact surfaces have to be squeaky clean.

Cheryl's avatar

Your articles are a blessing to me. I'm post spine surgery #16...10+ fractures, 4 fusions, nerve transfers...6 discs going bad...AS, parathyroid tumor, now gone, (long undiagnosed)...and today, I was utterly miserable. Read your articles, and remembered I have a jar of the DMSO gel. Put it on an hour ago...it's working. God bless you! Words cannot explain the hope I now have.

A Midwestern Doctor's avatar

It is so messed up this has been kept from people for over 50 years...

Cheryl's avatar

Sorry I missed this..I saw my quote and was thrilled that more folks will see it and try it!

K johnson's avatar

Thank you so much for taking the time and effort to write these posts. Your posts have really opened my eyes as a physician to learn about innovative therapies that we were not taught in medical school or residency. I am excited to see how DMSO helps my chronic conditions. I forwarded your previous article to a friend who recently suffered a concussion due to a bike injury. She started DMSO last week, and I hope to share a testimony from her soon!

WonderCircle's avatar

So so grateful for you and your work! You provide true abundance!💖

I so hope this can help my friend who routinely hurts herself exercising due to EDS. Read your research on EDS and am so grateful for that too. Peace be with you. 💕

Shirley's avatar

Please, please do! I have suffered from tinnitus for 6 years now after a horrible virus attacked my ears (I have suffered often from ear infections since I was a child). The time and money I spent going to ENTs. Ugh. But as soon as you get to the word "tinnitus", they punt and send you to a different specialist. The only one who was honest with me was my dentist, a DMD, who simply said that doctors (and dentists) are uncomfortable with things they don't know.

I am a musician (singer/choir director) and have hyper acuity. I cannot begin to say how awful of an affliction it has been.

Zoo_Tot's avatar

I have seen an improvement in my tinnitus by swabbing 70% DMSO/aloe gel mixture behind my ears. The noise level has gone from 7/10 to 4/10 in just a couple of weeks.

jenny d's avatar

I have been suffering with Tinnitus for years now. I would test DMSO starting today if i could decipher the articles to create my own spray. but in this research, it appears it was topically applied and injected. Do you recommend a doctor involved in trying DMSO for Tinnitus or would the topical spray in the external ear canal suffice?

Susie Arnett's avatar

there were many ingredients in the spray, how do you think it would work with just the DMSO? are the other ingredients important too?

RU Pondering's avatar

You can get some of the ingredients on Amazon (GABA and BHB). Personally, I’d recommend caution and a much smaller list of (natural) ingredients or waiting another week or two to see what the good doctor recommends. Applying this cocktail to or behind the ears is going to carry some portion of it directly into the brain.

Traci Edwards's avatar

I saw even Tractor Supply has DMSO. But decided to wait to see what the doctor recommends first. Anxious!

PapaJefe's avatar

Would this also apply to tinnitus related to Meniere's Disease?

A Midwestern Doctor's avatar

But you can view it at the link I just left.

Tina Blease's avatar

Tinnitus: If I get my own bottle of liquid from one of the companies you recommend, would I apply just a bit of the liquid behind the ear? If so, should I dilute it a bit or is full potency OK? How often daily? Is there a maintenance amount recommended? Thank You in advance for all that you do! ❤️

Thinking Mama Bear's avatar

Following. My tinnitus is quite LOUD this week.

VictorDianne Watson's avatar

Dear AMD,

This is a testimonial in the use of DMSO. I am an 81 year old woman who was injured by the first of a series of 2 Shingrix shots in 2019. I never took the second shot. Eight days after receiving that shot I developed excruciating pain in my arms, hands, legs and feet. Although being told by two doctors that the vaccine did not cause the pain, the neurology team at a major medical institution diagnosed my condition as acute inflammatory demyelinating polyneuropathy(AIDP), on the spectrum of Guillame Barre. They treated me with gabapentin which relieved the pain. However, I was left with neuropathy in my feet which caused severe and painful spasms in my feet along with numbness on the bottom of my feet. After several weeks seeing a neurologist, I asked her what could be done to help this situation. She said there was nothing. After this article I started using DMSO on the bottom of my feet and over the tops of my toes when I went to bed. The first time I used it, I had no spasms which always happened at night when I was trying to go to sleep. I’ve now used it for 3 days and still no spasms. It’s like a miracle. I’ll continue using it to see if it helps resolve the numbness in my feet. God bless you, AMD. I never would have tried this without your articles and would have suffered needlessly forever. I owe you a great debt. Thank you. I’m telling everyone about DMSO and sending your articles as well. Your contributions are, without doubt, some of the most important I have read.

A Midwestern Doctor's avatar

Thank you! I was going to get to that later in the series, but DMSO is really effective for post herpetic and shingles neuralgia, and since the shingles vaccine is live, that might have been part of what happened to you. Can I use your story?

Auntie Claus's avatar

My Dad is a physicist, but in retirement began experimenting with DMSO to treat medical problems of family and friends. He used DMSO as the “solvent” for various medicines, to apply them directly to the location needed. Acyclovir + DMSO to topically treat shingles and fever blisters for quick healing …. pain from shingles would subside in an hour, and the blisters would melt away within 24 hours. Used other formulas to treat athlete’s foot, plantar keratoses, plantar warts, diabetic foot infections, etc. He teamed up with a doctor at a VA hospital to successfully treat painful growths on amputee limbs from prosthetics … that was stopped by the VA when they found out. Sadly, my Dad has developed dementia since contracting COVID in 2020. We’ve used on-going Ivermectin and Lion’s Mane to slow and manage his dementia (along with intermittent fasting) … so I’m very excited to try the topical DMSO to the scalp to see if he can benefit from that.

Ron Heidary's avatar

Watch this TedTalk: Dr. Newport's husband Steven was diagnosed with early onset Alzheimer's, as a Doctor herself, she explored routine treatment options. Also, look at the Medical Medium Brainsaver book.

Auntie Claus's avatar

Great comment, Ron - thank you. We did read through Dr. Newport’s books and tried coconut oil. ALL of us had ferocious diarrhea from the 1-2 Tablespoons of coconut oil dissolved in hot cocoa (it was delicious, but …). The parents point-blank refused further experimentation with coconut oil. MCT oil (refined coconut oil) was even worse. Tiny amounts, gradually increased would have been a better approach, in retrospect. I have been wanting to look into exogenous ketones to see if that could be better tolerated.

An aside: my husband was the Guinea pig with coconut oil in his coffee - he didn’t have any gastro problems. However, it definitely affected his brain negatively. He’s mentally sharp right now, but when he took 2 Tbl. Coconut oil a day for 10 days, he started becoming unable to find the right words and even used incorrect words at times. It seemed to trigger brain fog in him!

Satan's Doorknob's avatar

Oils in coffee: I do this every day. My daily intake of fats/oils as supplement currently includes 1 Tbsp each of unrefined coconut, extra virgin oil oil, my "Omega 3" blend (equal amts of Flaxseed/ fish/cod liver) and 1 Tsp. black seed. Any of those, with the possible exception of the fish oils 😐, make interesting coffee beverages (blender required for best results). Obviously other beverages could be used, too. Use flavorings to add interest. Since I drink several cups in the morning, I fancy that I'm "earning" $30-40 dollars in money "saved" by making these exotic coffee drinks and not paying Starbucks prices. One downside of my frugality is I don't get the full cafe experience, which would be arguing "woke" poltics with a rainbow-haired person of indeterminate sex whose face looks like he/she/they fell into a box of fishing tackle.😁

Thomas A Braun RPh's avatar

DMSO is cheap and not patentable. You can't bottle sunshine, so they discredit the value of Vitamin D and create the fear of skin cancer. Researchers have found that there is a gene that needs Vitamin D to turn the gene on and produce a substance called E-Cadherin to prevent metastasis. Envelopes the tumor as a protective barrier. DMSO in my view is an excellent vehicle for transporting essential blood components to areas of congestion within the body. It's like Vitamin E which is a known oxygen transporter. Found the following use within oncology: Dimethyl sulfoxide is a reversible mitogen-activated extracellular signal-regulated kinase-1 (MEK1) and MEK2 inhibitor used to treat certain types of melanoma, metastatic non-small cell lung cancer, and locally advanced or metastatic anaplastic thyroid cancer. My question is if it would be a good transporter of chemo drugs in micro doses directly to tumors with positive results. Rather than having them applied systemically and having negative impact on multiple bodily functions.

Michelle's avatar

Your writings are such a gift. Thank you for all of them.

GaryP's avatar

Update to a previous comment on DMSO. I mixed up an 80% solution of DMSO for topical treatment. It is a very reactive solvent. Mixing with water is quite exothermic. The solution became quite warm. I would compare it to diluting HCL acid. The strong mineral acids, HCL, HNO3, and H2SO4 are available in the strongest concentration possible. HCL is available at 37% concentration, as that is the maximum amount of HCL that can be dissolved in water. These acids, at maximum concentration, all cause fumes to form in the air as the excess pure gas reacts with water in the air.

Anyway, I have been treating my wife with stage 7 Alzheimer's for 5 days with no noticeable results. I did not expect anything quickly and will continue the treatment for a month. Topical treatment around her neck and throat. I also treated myself with a stressed knee and wrist. The knee injury was a one time injury caused by putting my full weight on a completely bent and maybe twisted knee. A week ago I could not do lawn work, quit and applied ice. It was already on the mend when I applied the 80% solution of DMSO. Today, the knee is fine, no pain, stiffness, or anything. I have been wearing a wrist brace for weeks. After a couple topical DMSO treatments at 80% I feel no pain in that wrist. That was a repetitive stress injury from last spring. The brace was helping, but after two topical treatments with DMSO I am feeling no pain or stiffness from my wrist. Maybe a bit of weakness, so at least one more treatment.

The exotherm from mixing with water indicates that 100% concentration is likely to cause irritation as it reacts with water in the skin. Unless otherwise tested, 100% concentration should be limited to one time, emergency use in topical applications.

BW's avatar

Has your wife shown any improvement after a couple months of DMSO treatment?

Garhett Rittenhouse's avatar

Good info on the knee and wrist. I used 100% on shoulder (but have been using diluted for awhile...MWD indicated you do get used to it). Burned pretty good...basically, high irritation but pain dissipated after an hour or so (as did the burning).

swimmingupstream's avatar

I was pleasantly surprised to see Doc Bowen mentioned - I grew up in the same community as Doc and he was my maternal grandmother's physician before he went to DC. I recall my paternal grandmother (and other folks in town) used DMSO, probably purchased from the feed store, and the "garlic" smell. I'm getting painful arthritis in my feet and ready to give it a try. I really appreciate the brand recommendations and dosing tips. Thank you very, very much for doing the exhaustive research on this.

A Midwestern Doctor's avatar

Thank you! If you know anything else about Dr. Bowen I would love to know so i can include that in the next part of this series.

swimmingupstream's avatar

Are you wanting to know more about his involvement with DMSO or influence in the community? I know he was well loved and respected in that little town. It was a badge of honor to be a "Bowen baby" (a baby delivered by Doc at the local hospital) as he ventured out into politics first as Governor of Indiana and then of course serving under President Reagan. And his wife bought a set of dishes at my grandmother's garage sale, lol. My sis was a "Bowen baby" and I'll see if she remembers anything about him. I left that area after college but she remained in that community.

Singing in the Dark's avatar

For about a year, I used to take 75 mg iodine daily, as part of my treatment for Hashinoto’s, but now am off all meds and supplements the last 8 weeks, so my new Dr can see what my body will communicate to her, without any masking of symptoms. (I was also mega dosing D & K2 according to Coimbra’s Protocol).

The last six months, however, I have been combining DMSO with Lugol’s iodine tincture, and applying several drops of it to my thyroid a couple times a day.

For the last two months, I have been off of Armour Thyroid, 90 mg daily, after gradually reducing my own dosage (90-60 a few weeks, then 60-45 a couple weeks, then 45-22, then stopped taking any.)

In a couple days I will have my TSH and other numbers checked in lab work,and will know more about what is happening. Regrettably, I battle RA too, as well as other health issues, so it is not a simple matter to pinpoint what makes me feel badly on any given day.

Back to the point: I do not feel as horribly as I feared I would by now, when I began this experiment. A couple weeks ago I also added a small amount of birch oil (another anti-inflammatory agent) to the iodine/dmso mixture, and I can feel a difference in the pressure in my throat, around my thyroid, for a couple hours after applying it.

I haven’t been able to figure out how to relieve the RA pain with dmso. Dissolving a TBSP borax laundry powder into a couple ounces hand lotion and applying that has done more for my hand/joint pain than dmso has, this far. But I most certainly believe DMSO is a critical part of what is restoring my thyroid function and well-being.

Citizen_Jimserac's avatar

Thank you for posting. I have Hashimoto's and take 90mg of Armour Thyroid daily.

I read of your experiment with interest. My field is herbal research,particularly Chinese, and my Hashimoto's as well as that of my ancestor relatives who eventually died from it, undiagnosed, because years ago thyroid panel blood tests were not readily available, despite them having glaringly obvious classic symptoms, is what got me started in it.

Though there are known herbal protocols, both Chinese and European. successful ones, for Graves disease, I have yet to find anything other than taking hormone replacement therapy for Hashimoto's. I did stumble across a Chinese doctor in the 1600's whose name I've forgotten who treated patients with dessicated sheep thyroid, though he had no idea of the endocrine system or what it might have helped some of his patients.

The herbal information and solutions to many things are out there. For example, the brilliant Amirdovlat of Amasia was an Armenian Christian whose medical works and fame became so great that he was appointed chief medical officer in Istanbul in the 1400's. His book, "None by the Ignorant", available only in middle Armenian and in Russian translation, as far as I know, was a compendium of the major healing herbs with their names in Arabic, Latin, Greek and several other languages along with properties and use.

The problem is that these things are documented in obscure or archaic languages, forgotten journals and manuscripts, hearsay reports scattered across history. The coming of the Internet made such research possible.

Singing in the Dark's avatar

I’m so sorry you battle this too. I wish you didn’t, but I want to tell you, and encourage you:

reading how you describe your situation, and your ability to take a macro-view of your preceding generations, and incorporate what is good from other world-views while able to set aside what isn’t helpful for right now, without stumbling over it all….

I am convinced you have the intelligence and determination, and also the rare wisdom that comes only from respect and appreciation for your body and its beautiful design, to ultimately beat this thing and take back your health.

I want to see you win. ❤️

Henry Skelton's avatar

My wife has Hashimoto’s. I have 99% DMSO. Please tell me the quantities of Lugols and DMSO you use for your treatments. Thank you.

Singing in the Dark's avatar

Sure. I’d have no trouble believing there is a lot of room for variation of the proportions.

1/2 Lugol’s iodine solution, 2%

1/4 dmso

1/4 aloe Vera juice, to dilute the dmso. I am very sensitive to it and had to build a tolerance.

I smear 4-10 drops on my thyroid and around my lymph nodes under my neck at night when getting ready for bed. The iodine spot is gone by morning.

My best to you and your wife.

Singing in the Dark's avatar

Hi Darlene. No worries—if you’re wondering, so are possibly many others. Thanks for asking so I could know I need to clarify.

A better way to say it might be:

2 parts lugols’s iodine

1 part DMSO

1 part aloe vera juice

That way, whether you’re working in drops, ml or teaspoons, you can make it according to how much you want to work with.

Darlene Lessing's avatar

When you say 1/2 iodine solution what is the 1/2? 1/2 a tsp, or TBS?

1/4 dmso ?

You want the final mixture to be those? I’m sorry I’m confused. Thank you

Tilly's avatar

How did your results come back?

Singing in the Dark's avatar

Thanks for asking. I’m still trying to make sense of them. They’re not what I wanted them to be, to be sure.

My appointment was delayed 3 weeks by my Dr office. So I was off all meds and supplements for a couple months, instead of @three weeks, before my labs were drawn.

The good news first: I no longer have RA. I am still ANA positive, speckled, etc. but the antibody numbers are half what they were, and they are not RA antibodies now. I feel that difference, even though I don’t know exactly what I’m feeling. I feel…less “already dead”.

The bad: I still am very much a Hashimoto’s patient. I needed thyroid hormone, and I needed a lot of it, when they drew my labs.

The weird: I had no idea I was so bad off re: thyroid hormone. I felt so much better, even two months off everything, than I did 6 months ago on everything, I was shocked, and so was my Dr, who has watched me go from dragging myself into the office and unable to finish sentences, to back to myself. Also, I had, beginning a month before the lab draw, dropped the twenty pounds I picked up last year, even on my thyroid meds, my energy levels were better, though not what they were before 2022.

So 3 weeks after resuming thyroid meds, and resuming the iodine, I became hyperthyroid (evidenced by tachycardia) and we cut my thyroid meds in half. Now I feel better, although I was crushed that I got rid of RA by trying to treat Hashinoto’s. You deserve better information, but that is all I can offer right now.

I am ingesting DMSO now, by filling gelatin capsules one at a time and downing them with water and my supplements. It takes a steady hand and one has seconds to work before the DMSO dissolves the capsule. Why would anyone want to know this? Bc I battle MCAD as well, and my lower GI from my descending colon, down, will swell shut in response to stress (histamine). The DMSO has begun to work to relieve that inflammation and now I can eliminate the toxins instead of hold on to them.

A 00 capsule holds 1 - 1.25 ml (roughly 20, maybe 25 drops) DMSO, or about 1/4 tsp.

A 000 capsule holds nearly 40 drops (the larger size makes it more brittle, and takes longer to count and fill, so you risk dissolving it before you finish filling it if you count the drops into it). This is roughly 2, maybe 2.5 ml (half a tsp) per capsule.

Taking it by capsule reduces the DMSO Breath for me dramatically. I wonder if it helps get the DMSO down a little farther to my lower GI before it’s used up, desperately needed elsewhere, and I don’t know how to find that out, but I wonder.

Bc I struggle with MCAD and the brittle cornea problems that go with that, I have been making eye drops for myself that are overall from a base of store-bought rehydrating drops, 10% DMSO, a drop or two castor oil per 100 mls, and .015% half low-, and half high-molecular weight hyaluronic acid. The DMSO always stings, bc I have nearly no cornea between my nerve endings and the rest of the world; there’s no getting around that. But I use these drops several times a day, bc I have no corneal interface for tears to cling to, and the floaters I couldn’t see through or around, bc they’re always so numerous and large, are steadily dissolving the last two weeks I’ve been using these drops, and I can see better.

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Tilly's avatar

That's exciting progress! I'd rather have Hashimotos than RA, but I'm a sook about pain haha. I've been reading that Nigella Seed Oil reduces thyroid antibodies so maybe the Birch you tried helped with the RA antibodies too? If DMSO makes everything you concurrently take stronger that might be why you don't need as much thyroid meds and iodine. My sister read that when you are on keto or in ketosis (say by intermittent fasting) you don't need thyroid hormones as much, so if it happened I ran out of meds I should go carb free. That would be a sad day for me, but maybe that helped when you were low thyroid but feeling better.

I was reading Dr Christianson's Thyroid Reset and he had a totally different idea that made a lot of sense while going against the accepted wisdom. When you get a bunch of iodine or fluoride or even bromine that's actually too much for your thyroid and it will shut down rather than wear out your heart and kidneys. But then you have to really deplete that stuff to get it going optimally again. So instead of taking iodine he has you avoiding it. That is very difficult but people have had success there and it's not harder than stopping eating at 4pm when everyone else eats normally.

Anyway I will message again for an update in a couple of months to find out how you're going. It's very encouraging to see that progress.

Singing in the Dark's avatar

Thank you for those recommendations. I’m going to look into Nigella Seed oil, and Dr Christianson’s thyroid reset—because we’re all missing puzzle pieces and these could be what I need most.

Thank you for your kind and compassionate interest, and supportive words. I almost hugged my phone, reading them, lol. I appreciate you.

vharlow@harlowhome.com's avatar

If I already responded, this is just additional. My husband has quit using cbd gummies for pain, and now I just rub his back and shoulders. No question he's in less pain. And I've been putting it on my badly arthritic knees which are so bad getting up and down is difficult, and kneeling in church is out of the question! Until I tried it today! NO PAIN! kNEELING AGAIN! Oh, they still don't work well, but the PAIN is gone.

April's avatar

I wanted to cry watching the 60 minute interview. Ah the days of "real" investigative journalism. Just tell us the facts. I am so glad to have found you and your substack. As a retired Pathologist Assistant I love learning these forgotten gems

A Midwestern Doctor's avatar

If you really want to cry, watch all the reports they used to do on vaccine injuries:

https://www.midwesterndoctor.com/p/why-does-the-government-cover-up

Stoney's avatar

Thank you for this behind the scenes info. Do you have a link to Dr. Humphries full series on vaccines: Honesty vs Policy. You only link chapter 4 (which is very well done). I checked Dr. Humphries site, and around the internet but all of her youtube videos have been removed due to "violating community standards"! This would be much easier to share than getting someone to read her book Dissolving Illusions.

A Midwestern Doctor's avatar

It's all on her odyssey channel

Stoney's avatar

Thank you MWD. For all who have the same question the link is:

https://odysee.com/@drsuzanneh:f?view=content

Pam M's avatar

So very grateful for what I would imagine to be massive amounts of time and energy you must put into these articles. They can give us wonderful resources and hope in dealing with health challenges especially when main stream medicine seems to be working so hard to keep us in poor health. Many Thanks!!

Tech girl's avatar

I’ve used DMSO for back injuries and it’s amazing. Curious if DMSO helps kidney disease, specifically where inflammation is the culprit. A side effect is increased urination so wondering is it would simulate healthy function back.

Chantelle's avatar

Thank you for doing all the work to collect this amazing information and for sharing it with us! I finally have some hope that maybe I don't have to live in pain all the time. I went to see my GP today because the nerve pain in my feet is out of control. He prescribed a different medication but when I asked if we could try DMSO, he said no. When I asked him why he basically said that it was a carrier of other things through the skin but that on its own it really has very little therapeutic value. He said that when they fixed the problem of tasting garlic they also destroyed any therapeutic value. It felt like he was being patronizing and even making fun of me which he hasn't ever done in the 25 years or more that I've been seeing him. It was very clear to me that he had bought into the propaganda and the lies about DMSO. He did say that he didn't have any problem with me trying it on my own as long as I only used to topically, so that's what I'm going to do. I am going to read as much as I can and I'm going to get rid of the nerve pain in my feet:) Thanks for shining a light into my darkness and for giving me a reason to hope again!

RonK's avatar

What a remarkable coincidence! I have been dealing with a lot of pain in my knee and hip, left leg, from injuries that I incurred 50 years ago. I have been taking a pain med and muscle relaxant but they no longer serve their purpose. At my advanced age, knee and hip replacements are out of the question, so I have been limping around for the last 4 years, each year gradually getting worse. Thanks to your previous article on DMSO and the current one, I decided to try DMSO which I bought online. It arrived today just as I was reading your article, so I plan to start testing it tomorrow, hoping for the best but not expecting any miracles. FYI, the mfg of the DMSO is from a US company, DMSO AR Laboratory Analytical Reagent Pharma USP Grade JT BAKER, and, it is advertised as 99.9% pure.

Praveen's avatar

Could you share an update on your condition ?

Unagnu's avatar

Anything mostly safe cheap and effective is banned, ignored, de-funded or not pursuit. Be it for cancer, joint issue, chronic pain relief, you cannot have safe effective 'cures' or remedies... because then the huge big harma doesn't make mooola!

Eagleeye's avatar

Unlike so many practitioners who “hawk” their wares you provide authentic information which puts a patient in charge of their own care. I very much appreciate your work and will continue to support it because of your ethical values.

A Midwestern Doctor's avatar

When I started here, one of my goals was to never push supplements. I've held to that even though I've had some very enticing offers sent my way.

Eagleeye's avatar

Your response is, to my way of thinking, the most ethical. And greatly appreciated by all who read your work. I am reminded of an ophthalmologist collegue who once said, to paraphrase "my ophthalmology practice is my ethical medical practice but my advertised refractive surgery practice is to make money."

vharlow@harlowhome.com's avatar

My all time favorite substack! Going to try this for my husband with chronic back pain from failed surgery long ago! Wow! Thanks so much!

Marguerite Heyworth's avatar

1st day and I’m sold! I applied castor oil then rolled DMSO on my knee this morning. The pain calmed down in about 45 minutes. It reignited about 4.5 hours later so I reapplied and the relief was immediate. I haven’t been this excited by any product with the exception of a fabulous leather balm I bought recently and I jokingly told my friends I was going to put it in my coffee (after having put it on the backs of my hands). The beauty of DMSO is that it can be ingested! Thanks AMD!!!

Katherine Broyles's avatar

Thank you for this work - have you seen any research that suggests using dmso post joint replacement could cause any issues? Such as causing a leaching of metals into body or degradation of the implant - I thought I read something that suggested that could

Be possible in the healing with DMSO book. Makes me a little nervous about using it - Thank you

J T's avatar

I have the same question. Since Sept 2023 I've had both hips replaced, a knee replaced and a knee manipulation while asleep so the surgeon could bend the knee to break up scar tissue. With metal and partly ceramic/plastic joint replacements, can DMSO be used to heal the joints, break up internal scar tissue & restore range of motion (and stop the pain)? Any safety guidelines to avoid absorbing those foreign materials into my system?

Thanks so much to you, MWDr, so grateful for my new subscription.!

GingerRRT's avatar

Wife had the same problem with both knees. Used Chlorine Dioxide and most of the pain is gone. I assume it was inflammation. She still has one knee that bothers her a little, but can’t get her to try dmso because she smelled it on me🤣

robin hanna's avatar

good question!!! I was thinking about slapping some on ,my shoulders and hip but they are full of metal. I am also going to heed the pool/chlorine warnings since I am having such good luck exercising in the pool (walking lunges and squats are so easy and effective). my boyfriend is getting relief for his back ("pulled it out but no dx yet). I put it on my neck one time and I am pain free there. I am also thinking about using it with capsacin or cayenne.

Odette's avatar

Good question! Wonder about knee replacement having metals and plastic. Also wonder about titanium (which I had removed from all the pain it caused from tubal ligation - pain left after removal). Also I have one mercury filling left to get out. Wonder if DMSO pushes the off gassing of these metals deeper into tissues/organs.

MTown's avatar

N-1 case study of treating toenail fungus with DMSO + povidone–iodine solution:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599634/

Garhett Rittenhouse's avatar

Thank you for that link. My wife read iodine would help. Then, saw a youtube about using Vicks Vapor Rub. I've been using it four months and had the best nail regrowth yet. However, if it doesn't work (or gets resistant as the article mentioned), i'll be moving to the iodine/DMSO solution. Much appreciated!

Trent's avatar

Strange times we live in. I have more confidence taking health advice from an anonymous source on the interwebs vs. my MD who pushed the JAB and literally claimed it was safe because the tech has been around for 10 years. (no jab for me)

A Midwestern Doctor's avatar

I try very hard to provide all my sources and have it be about the information rather than me so lots of doctors can copy it and claim it as their own as that gives the highest likilihood this will permanently be in the culture.

Trent's avatar

I appreciate and applaud your efforts. I guess what I was trying to say is that none of us should be forced to hide in fear of being canceled, or in your case having your license revoked.

Connie Cook's avatar

Thank you!

Satan's Doorknob's avatar

Ulcers: Dr. Atkins’s Vita-Nutrient Solution (DMSO sections) covers much of the same territory as does AMD in this blog. However, he reports one study that found DMSO effective for:

“DMSO compares very favorably with the popular ulcer drug cimetidine. In one experiment, 220 people with a duodenal ulcer began to take 500 mg of DMSO orally every day. By the end of the study they had fewer than half of the ulcer recurrences experienced by people taking cimetidine alone.”

AMD says: “DMSO will react with metals such as aluminum, copper, iron, nickel or tin but not gold or silver”. This may be a consideration not only with jewelry. DMSO may well be reactive with these metals, but the important question is “How reactive?” I have experimented with topical application and aware of the potential issue of leaching of chemicals from plastic (e.g. bandage) I used a piece of aluminum foil between the bandage and a DMSO-soaked cotton ball next to skin. I’m not sure what’s the greater risk of unwanted chemical leaching; since I’m limited to materials on hand, I still would vote for the aluminum foil.

I am fortunate to live in one of the very few States (Florida) that specifically “legalizes” an MD to use DMSO. The patient is supposed to be briefed and then grant a written waiver of liability. Most important for the MD, the state medical boards are prohibited from punishing the doctor for prescribing DMSO. Doctors and hospitals are exempted from (all?) liability. I’m doubly fortunate that I don’t have any health conditions that would require such treatment (“yet”).

A Midwestern Doctor's avatar

I cited the ulcer study in here

Edward's avatar

2 months followup - DMSO 70% gel immediately help with pain reduction, and added MSM (3000mg daily) now the knee inflammation and swelling is down. also COOLER. starting to reduce dosages.

some of DMSO metabolizes to MSM and both are very similar.

so DMSO works from outside and MSM works from inside.

(Only this article of the DMSO series mentions MSM)

got rid of cortisteroids and pain killers drugs which don't really work and have serious side effects (Kept the natural formulations which include Willow White, Curcumin, Black Cumin seed oil)

PutativePathogen's avatar

First, I want to know how you continue so indefatigably! I'm a little worried about you ;)

Second, I had limited success with DMSO topical application for knee pain over a period of weeks. However, within 4 days of taking it orally, the pain is gone. (I initially took 2 daily doses of 1/2 teaspoon 99% DMSO (from a glass bottle) in green tea. Have reduced to 1 dose of 1/2 teaspoon, a.m., as it disagreed with me in the evening. Thank you for your thorough explanations of not only what, but how and why on every topic.

Third - do you believe that RFK Jr.'s throat/voice injury could be improved with DMSO? Do you know anyone who might forward information to him?

A Midwestern Doctor's avatar

I am definitely a bit tired at this point!

I have no idea about that one, but it is possible since it's a muscle spasm.

Evelyn's avatar

My 10yo has pans and we rely on ibuprofen to get him out of a flare. His flare symptoms include ocd and I just can’t bear to watch him suffer. He is 80% recovered through biomedical approaches, but he is losing teeth and growth spurting and flaring more than usual at the moment.

I am excited to try dmso as an ibuprofen replacement. I will try your migraine protocol. I happen to have ibuprofen from the dmso store in my medicine cabinet already! I have a recipe that uses it for castor oils packs, and I give it to him occasionally on his liver. I knew that the dmso drives the castor oil into the body without the need for heat, but had no idea of all these broader applications. If it works this could be huge for him!

Cynthia's avatar

Hi! I recently subscribed because of the amazing well researched work you do. Thanks for your efforts! I am trying to print out the full articles on DMSO-I retain way more info if I’m reading a hard copy-and can only print out the very truncated version that is available for free even though I’m signed in. Is it possible to print out the full articles? Thanks!

Garhett Rittenhouse's avatar

I think if you right click with your mouse you will see in the menu "Print"...my windows print screen popped up...then...you can select the Microsoft PDF printer (which will require you to save the doc), then it seems like you could print it. Good luck...

Cynthia's avatar

Thanks Garrett-I will give it a try!

Lisa Bruce's avatar

Thank you.

Mark Fulford's avatar

The article underscores my own positive experiences using DMSO

Courtney's avatar

Thank you for your service. The world needs you!

Philip James Paustian   MD's avatar

Once again fabulously useful information in your DMSO series to such a degree I felt compelled to reaffirm / re-up my paid subscription even while I try to cut expenses and save time. I am saddened and amazed as I keep learning about the effectiveness of therapies I was taught did not work or worse therapies never mentioned. May God keep you well, solvent, and able to continue your excellent work.

Laura's avatar

I would like to share that I've used DMSO on my rosacea for just three days and it is already reducing the redness!

Thinking Mama Bear's avatar

I used Ivermectin horse paste on my rosacea. I used a very small amount x 3 days. It mostly gone on my cheeks. Will try 2x more on chin.

LauraD's avatar

I am so grateful for doctors (like you) who are so willing to share your medical knowledge with the public so that we can take responsibility for our health. God bless you!

Mark Farris DDS's avatar

I have a rotator cuff injury that caused severe pain when I tried to sleep on my side, or raise my arm laterally. 70% DMSO on the pain area would give me significant relief for 4 hours. Amazing pain management. I mix mine with colloidal silver but distilled water is fine. Small amber glass dropper bottles, 4 oz., with a small stainless steel funnel is helpful. I also have a knee that starting hurting a bit after walking 2 miles a day for months. I take a few drops of 70% DMSO into my palm and rub it into the joint areas for a total of about 20 drops on the shoulder and 20 drops on the knee. I do my shoulder and my knee twice a day. I can tell a difference in comfort level and the joints are getting better over time. I have little to no pain in my shoulder now, I can sleep on my side again, I still have limited lateral elevation movement, but that has improved. My knee is 95% better. DMSO is a wonderful substance for natural healing promotion.

Eclectic Health's avatar

Thanks for an incredible article! I have used DMSO for injuries for years and have also recommended it, and everything I have seen is consistent with this article. For those who are going to try it for injuries (especially chronic injuries) I would say that while it may work in a matter hours or days, a reasonable expectation is to give it 10 days to two weeks at least. The effect (for me and others I know) is that its benefits "sneak up on you" over time rather than being like some sort of rapid-acting analgesic.

I also agree that it seems much less effective for hip injuries. I've had great success with those using something that claims to be a BPC-157 patch, however that compound is far larger than the 500 Daltons which I though was the limit for transdermal application, so I am really looking forward to your discussion of DMSO as a carrier and the physiology of what can be "carried" across the skin.

Perhaps most importantly, I think DMSO is a literal "gateway drug" for helping the general population see how much healthier we can be using existing treatments.

Lovejoy's avatar

I'm wondering if DMSO could help with the dental work I'm having done next week. I'm having a root canal removed. I wonder if the titanium implant on the other side of my mouth could react poorly with the DMSO - or possibly some other dental filling materials I already have?

Leila Kostyk's avatar

Great article! I appreciate the tips on getting it to the area topically, as it's next to impossible to find someone who will treat via IV here in Canada. My son has had strokes, and his parents are experiencing all the aches & pains of getting older, so I think that will help. I have tried taking it orally but it made me stink! The funny thing is, I had no idea, could not smell it myself. One really can't go out or be around people at all. But, in an urgent situation, I'd do it anyway.

Several years ago I was diagnosed with plantar faciitis, given exercises and advised to take analgesics for the pain. Being an impatient person, I decided to try DMSO instead. That was also around the same time I'd run across an article on anticholinergics and had decided to stop taking pain meds. I put DMSO in a shallow flat glass container large enough to fit my foot, washed my foot thoroughly, and soaked my heel. I'm not sure how long or how often, but it was enough that a layer of skin peeled off. Scary but not painful. There's been no pain in that heel since then.

robin hanna's avatar

what did you take in college for brain???? Thanks for all your work and helping us all, and me specifically, so much.

A Midwestern Doctor's avatar

The main thing was I tried to get out of college as quickly as I could because I realized it was making me less intelligent and less able to think

Katherine Quinn's avatar

Fascinating article -- thank you! I have an ankle tendon injury that reoccurs every time I ride my peloton bike and no amount of rest has worked, so I'm going to give the gel a try. On a separate note, my 28 year old son was diagnosed with IgA nephropathy in 2017 and on his most recent visit to his nephrologist, he was told that within 2 years he will need either to begin dialysis or get a kidney transplant. I have been researching the disease for years and only recently are drug companies making progress on medications that block (or limit) the overproduction of IgA that damages the kidneys. My son's doctor told him he is too far along to try any of those. Are you aware of any "alternative" information I might be able to read on this subject?

Auntie Claus's avatar

Katherine - diet can play a role in autoimmune disorders as well as kidney disease. Set aside some time and search / watch videos on YouTube by Dave Mac, Coach Stephen, Kerry at Homestead How (they have testimonials from people with advanced kidney disease improving through ketogenic/carnivore diets), Dr. Jason Fung, Canadian nephrologist (who pioneered intermittent fasting and ketogenic diet to reverse diabetes and help kidney disease patients), etc. Really hopeful stuff! You can change the diet without negative side-effects, while still pursuing other medical options - plus cheaper than medications!

Katherine Quinn's avatar

Thanks very much Auntie. I am a follower of Dr. Fung and also a big fan of carnivore, keto, lchf dieting. My son's kidney issues, differ from diabetes-related kidney disease and since he has been having gout flareups, finding the right balance with a keto-carnivore diet can be challenging. He lives in Maui and I live in New England, so he relies heavily on his doctor's guidance and as you can imagine, finding a mainstream physician -- especially a nephrologist -- who promotes keto/carnivore is not easy.

Atomic Handyman's avatar

I'm not sure this advice is relavent to IgA nepropathy as it concerns NgA nepropathy, but it may have some value. I have a friend that was diagnosed with NgA Nepropathy - not IgA nepropathy - some 20 years ago. He was told back then that he sould get his affairs in order because he wouldn't live past the next few years. When he gets a cold, his immune system attacks his kidneys and some blood becomes apparent in his urine. He asked about treatemnts and he was told by a Chinese allopathic doctor that he could use steroids or or take large doses of fish oil. No other doctor he spoke with mentioned fish oil. He has taken 12 grams of fish oil (including 300 mg of omege-3) spread out through the day for those 20 years. It moderates his system's severe immune response. He is surviving and watches his test numbers closely. For a period of time he was able to go on a very low carbohydrate diet and his yearly test numbers come back to something close to normal. So, the diet advice concerning intermittent fasting and ketogenic diet is sound. Strangely enough, though protean is hard on the kidneys, he can eat quantities of meat and not have it show in poor test numbers or symptoms. I'm hoping this will be of value to you or someone. You may need to do more research. Good luck.

Very good work on this DMSO information. I'm using effectively for my back and hip problems.

Atomic Handyman's avatar

My mistake. My friend has IgA nephropathy, not NgA. Here is his successful protocol. "IGA Nephropathy--take 12,000mg of fish oil, plus Lisinopril and Losartan Potassium to keep blood pressure low and try not to get sick. If they are having sore throats, removing tonsils may reduce infection and help. There is a new drug, Filspari, which may help--only costs $120,000 a year and is only offered to people with private insurance--not for Medicare or government insurance."

Garhett Rittenhouse's avatar

Sorry John...I had to delete my previous comments. They were inaccurate. So...hopefully, this is better.

Not medical advice: I took Cytoxan (drug name: cyclophosphamide) for my steroid resistant Minimal Change Disease (flared up twice). Highly toxic so you can only take so many grams for so long as stated by my nephrologist. If I needed a third time...we would use cyclosporine.

I'm sure his nephrologist knows about this stuff. And, maybe only for my specific kidney disease (which "knock on wood" is in remission)...but...damn if we don't learn by sharing :-)

Of course, offering this to the doc will probably get him nasty looks or beat up. Best of luck to him...and...thanks for the info.

Rosie Cotton's avatar

You may want to investigate Curious Outlier substack about Chlorine Dioxide as a solution for kidney issues.

Sam Miller's avatar

Some people have seen improvement in kidney function after spending time in an ee system check out the testimonials at https://www.unifydhealing.com/testimonials and search the word kidney.

Mrs. Itoldya!'s avatar

Isn’t there just a simple, one step application, just to treat arthritis? I do not want to be a chemist, mixing up concoctions on my kitchen counter. All these options & variables, send me running away like mad! Just a simple starting point? Same with FenBen & Ivermectin dosing!! Insanely hard for a simple, very busy self employed grandma to try… I put no lotions on my body, only shower once @ week using organic soap, take no medications, but joint pain & deformities are getting worse… Do I need to find a homeopathic doctor? I’ve grown to dislike & distrust almost all of the medical community..

A Midwestern Doctor's avatar

The simple version is to topically apply 70% and if that is too irritating, to dilute it with purified water.

Mrs. Itoldya!'s avatar

I saved all your Amazon links, but do not believe any of those were a 70% diluted version..??

A Midwestern Doctor's avatar

The liquid nature's path one is

Gaily's avatar

On Amazon - Natures Gift DMSO Gel with Aloe Vera is 70% DMSO and 30% Aloe Vera.

BK's avatar

Don’t get carried away. Remember, half of the pharmacists graduated in the bottom half of their class.

BK's avatar

Take two tablespoons of 99.9% pharmaceutical grade DMSO and mix with one tablespoon of distilled water = approx 70% solution (67% to be more precision; 66.667% to be exceedingly precise).

Mrs. Itoldya!'s avatar

And drink it?? I bought both liquid & gel & have applied it just topically. https://a.co/d/itjpT3g

BK's avatar

I have only used topically and do know that the product is readily absorbed, so I would continue what you are doing now. After a few days of tolerating, increase either the amount used or the number of times used per day and see what happens. I’m a pharmacist, but one who sees the medical establishment for what it is, snake oil salesman.

Garhett Rittenhouse's avatar

As an aside to drinking it...I use 1.5 tsp in an 8 oz glass of water. I do that three times per day. MWD said start with only ONCE per day...I think he said three days...then add more times, if necessary.

But, I think Mr BradfordK probably knows more...he's probably right :-))

Best of luck.

VeryVer's avatar

I feel the same -- and I worry that I'll mess it up and have to go the ER and tell them, "I read on the InterWeb how to make my own medicines..." lol.

Adrienne's avatar

Thank you! Eager to read more about the effects on eczema as I have several family members who struggle with that.

I am also wondering if anyone has used this to treat lymphedema specifically as opposed to swelling from an injury or the like.

VeryVer's avatar

I’d like to try it for my heel spur but I’m leery of buying from the internet. Has anyone else personally used these brands?

A Midwestern Doctor's avatar

I have used the two amazon ones a lot.

GertrudeC's avatar

Heartfelt thanks and appreciation from a ND - the time, effort, diligence and courage all your work takes is exceptional. A brave and conscientious soul!

Within two applications of topical 35% a pt is completely pain free after 7 years of prepatellar bursitis. Thank you so much! Now to try it with some Down’s syndrome cases.

Marie's avatar

Thank you for such a great article. As far as DMSO for Tinnitus. Where would you apply the DMSO? Thanks again.👏👏

A Midwestern Doctor's avatar

Will get to that in a later article

Chris's avatar

Excellent research - I've given DMSO to my mom and it has helped her arthritis immensely. I was wondering if you would be able to do a paper on Red Light Therapy in the future, and recommend the best ones on the market, and what benefits one will derive from its use. Thanks.

A Midwestern Doctor's avatar

I like Inlight therapy. Might be better ones but those are great

drea's avatar

Chris — please tell me how you using it to help your mom’s arthritis. I would like to try the same method. Thanks.

Chris's avatar

I gave her first of all some 70% DMSO gel to apply on the back of her thumbs where she has pain. She just rubs a bit in and says it relieves the pain immediately. I have now also given her 90% liquid DMSO which she is applying instead and it is also working for her. I hope that helps you with your arthritis also.

Pamela K Hayes's avatar

I used to use DMSO years and years ago but can't remember what strength, and such. I ordered some 99.9%. Do I dilute with distilled water/ratio? Sorry my older mind is failing me on the protocol. Any tips welcome I know the doc can't prescribe. Thanks!

Chilly's avatar

How did you give the DMSO, tropically? My wife has very bad arthiritis in her hips, they want to do both hip replacements, so I am interested in anything that would help before even considering surgery.

Don Midwest's avatar

I have started taking 1 teaspoon in 8 oz of water and it seems to have helped my hip

Ned B.'s avatar

AMD said on another thread: Psoriasis is one condition where DMSO sometimes makes worse rather than better.

Renee C.'s avatar

I hope so. I know the Doc said in an earlier comment that Psoriasis can sometimes get worse when taking DMSO but I'm wondering if that's a temporary thing (worse then better) or no? There's got to something to get rid of this horrible disease.

Michelle Sebastian's avatar

I’ve read that KPV peptides works for psoriasis. I’ve been searching for something to help my daughter heal from another chronic skin condition called hidradenitis.

Renee C.'s avatar

Thank you, Michelle, I'll look into that! :)

Dan Star's avatar

Get liquid, dilute with aloe vera down to 20% strength then adjust as needed.

Patricia Worthington's avatar

How do I obtain DMSO? I thought that might have been mentioned. I have a "patient" in mind for it

Ned B.'s avatar

I buy 99.995% pure DMSO from the DMSO store on Amazon: https://www.amazon.com/DMSO-Bottle-99-995-Dimethyl-Sulfoxide/dp/B01BSYQ0XC/

The Midwestern Doc recommended it in an earlier article.

TheDude's avatar

What a fabulous article and I sincerely appreciate your attention to “forgotten” and maligned therapies. I have been a very active athlete until the last few years (I’m 61) and have developed a Morton’s neuroma on one foot and possible rotator cuff injury.. I am hopeful that some DMSO may help both those conditions and get me back to enjoying my workouts/races. I am also particularly intrigued with your writings on zeta potential.. fascinating data and great explanations with links. Bless you!

A Midwestern Doctor's avatar

Thank you. In a lot of cases with morton's neuromas you also need to do something to strengthen the foot so the metatarsals stop rubbing against the nerve and inflaming it.

Gogs's avatar

What a wealth of very useful information - thank you! How would one apply DMSO for tinnitus, I wonder.

Big E's avatar

Dear AMD, you are singlehandedly saving the world from great suffering and potential death from pain-induced suicide. I hope our government agencies don't get wind of DMSO's life-enhancing properties, classify it as a dangerous drug, and then ban it. (Shades of ivermectin, and hydroxycloroquine methinks.)

I've shamelessly taken liberties to create a Substack note with an overview of this article. I hope to get people reading about and using this amazing, life-enhancing substance DMSO. I've already passed the article and note along to a wound care nurse and a key person within the "vaccine" injured community. These folks have many contacts and I hope they will share the news widely.

Here you go! https://substack.com/profile/68304299-big-e/note/c-70829876

A Midwestern Doctor's avatar

Thank you! Sorry about the animals :(

Jamie's avatar

I spent most of my life working with animals.

I switched from the allopathic medicine model after I had to stop working full-time and treated all the animals in my care with natural alternatives and food. I am definitely a bleeding heart when it comes to all innocent creatures, however, I’m very grateful for their past service.

My research started to help them heal and has now changed my health and healing in profound ways.

Crabjo's avatar

This observation is small ball compared to the World Series level of this article, but I wondered if you might want to amend this note a little…

“Note: there have also been reports of DMSO being able to eliminate birthmarks.”

Based on the article you linked as a reference for that one, it seems like the pulsed dye therapy is technically what did the eliminating, but the topical application of lidocaine + DMSO allowed the patients to endure the pain associated with that type of removal therapy.

A Midwestern Doctor's avatar

Thanks for catching that. I didn't word that correctly and it's fixed.

T Jay's avatar

Most all of the DMSO products are shipped in plastic. I am curious on what you thoughts on the plastic breaking down resulting in microplastics in the DMSO. I would think this would be a problem since the DMSO will pass thru the skin and possibly thru the BBB. Maybe I'm not understanding.....

A Midwestern Doctor's avatar

Fine with gel, for liquid I think it should be in glass.

PutativePathogen's avatar

My understanding from her various writings, and some great comments, is that, over time, plastic break-down can be an issue. DMSO is essentially a solvent. I can't speculate on the safe "shelf-life", though. I use the plastic bottles for topical, and have recently ordered DMSO in glass bottles for internal use.

MKiley's avatar

What is the dosing for drinking DMSO and what is the dosing for IV DMSO? How do you find IV DMSO providers? What are the benefits of DMSO taken orally and by IV?

Sam's avatar

I've got subacromial bursitis from falling backward on concrete and putting my arm out to stop myself... anyway, it flared up and was really bad - no movement, mucho painful, but I've been putting dmso cream on, to start it was my whole arm and shoulder, back and front, twice a day. So, so happy to report, it's got better so now after about 10 days, I just put it on my upper arm, once a day.

I intend to take a couple teaspoons daily (diluted in a drink, maybe juice) dmso, just waiting on the order. I have a couple of minor aging issues and I think this may be just the ticket! Great Stuff! Thank you MWD, thank you, thank you 🙏🙏

Craig's avatar

So grateful to you, MW Dr, and others with courage and compassion, like you!! ❤️ I’ve had some recent success with a pure DMSO “roll on” product from DMSO Store from Amazon. It’s easier to apply than the liquid and seems to have slightly less odor.

Champagne's avatar

So I ordered 100% DMSO (from the DMSO Store) then reread this article about using a lesser %. When you say "dilute"-- by what means? Distilled water? Tap water? Aloe gel? Lotion? (see quote from article below). My immediate uses are osteoarthritis in a big toe joint and nerve damage at my tailbone from a previous cyst. Thank you!

"Many of the DMSO products on the market have 70% strength formulations. In turn, if you plan to do topical DMSO, you either do the same or start with 100% and very carefully dilute to the amount you need. Additionally, while most people can tolerate 70%, to make sure you are not a particularly sensitive person, I would start with a 20% dilution, make sure that is fine for the body, then gradually raise its concentration (e.g., 20%, 40%, 50%, 60%, 70%) and if at 70% it doesn’t seem like anything happened, try slowly raising it to 90%."

J Pattison's avatar

VERY IMPORTANT QUESTION: HOW LONG WOULD SOMEONE HAVE TO BE OFF NARCOTICS FOR CANCER PAIN BEFORE TRYING DMSO? Since the DMSO intensifies drugs, would someone have to be off of narcotics for a full 5 days (the length of time for it to get out of one's system)?

Molly's avatar

Where can I find Food Grade DMSO or do I even need Food Grade. The bottle I bought says it’s a solvent. Can you recommend a brand?

A Midwestern Doctor's avatar

"Food grade" does not exist. You just want high purity.

Cca's avatar

Having a problem understanding the doing. When you use a brush you dont control the dosage at all. What doses are used topically in ml?

A Midwestern Doctor's avatar

That varies so much I didn't specify it.

Justin Shive's avatar

My mother has severe osteoporosis and back/leg pain stemming from disc issues between L4 and L5. Would applying DMSO to the L4-L5 region assist in pain management or even help the disc regenerate? She's being told that surgery is the only option.

A Midwestern Doctor's avatar

In many similar cases it has.

Moi's avatar

Justin, it would not hurt to try DMSO. Back surgeries in general seem to produce more problems than they treat.

Sam Miller's avatar

Dr Brownstein writes that he reversed Osteoporosis in his patients by telling them to supplement with 5,000 iu of vitamin D and some vitamin K daily, (I don't remember how much). Additionally, he recommends eliminating acidic foods such as white sugar, refined flour, and dairy, as well as junk food, and increasing consumption of alkaline-rich foods like fresh fruits and leafy vegetables.

Moi's avatar

My husband has early white-matter disease (like his parents) and since devouring your DMSO articles I've been giving him a few milliliters DMSO orally daily. He's been fine with it but suddenly I'm wondering, since it is a solvent, if oral DMSO might have detrimental effects on the intestinal biome. Any thoughts?

You are an inspiration, MWD.

A Midwestern Doctor's avatar

I think it changes the microbiome, but I do not know if this was ever researched. Let me know if there are any changes.

Moi's avatar

Will do. I'm going to alternate a day of oral consumption with one of topical neck application, trying to enhance that blood flow. One reason white-matter neurons die might well be lack of sufficient blood-borne nutrition.

Derek P's avatar

I have been a subscriber for several months and please continue this great work. I am very appreciative of the effort you put into each report. Just a quick note on DMSO sources. i used the DMSO Store via Amazon and ordered 70/30 liquid. i chii ok se this brand as it was advertised and shown in a glass bottle. But it arrived a few days later and it was in a plastic bottle. FWIW

A Midwestern Doctor's avatar

Oh that's really bad...

Any chance you can contact them and tell them to cut that out, if not they aren't getting recommended anymore. Also, is it possible you made a mistake in the order because we've never had that happen here.

Derek P's avatar

Hi update. it was ordered correctly . it was advertised as a DMSO store brand. But it was sold on Amazon by another seller. This seller has some bad reviews. I reordered directly from DMSO store this time. It's the first time in a decade if arderá from Amazon that this type of incident occurred. Thank you for your reply. As a 30 t year student of natural health (with much success) i again want to thank you for your hard work and reports! I've supported Trump in the hopes that if he's elected then RFK can get to work and start correcting our food and medicine.

Cyber Unknown's avatar

Dear fellow appreciators and - (thanks to the incredibly hard work of our shared doctor) - users of DMSO: Can you help me? I sincerely need simple (?) steps in how to apply the gel to husband's herniated (possibly ruptured) L1 disc. It sits atop total spinal fusion from L2 through lower spine S1 tailbone. I am not clear on recommended dose or number of applications of gel. I do not understand if liquid is appropriate. (I have the products Dr. recommended as ones he had used in 1st article.) One try resulted in him complaining of skin irritation (he is a redhead) and so did not reuse. Can either the esteemed doctor or fellow patients offer me clear guidance? After several years, and now with the addition of the L1, this man's life is evaporating from within and without. The only thing I know is to check back in the comments for any help offered. Thanking you most sincerely.

A Midwestern Doctor's avatar

He needs a lower concentration.

Cyber Unknown's avatar

Late from me, but THANK YOU!

Anne in NY's avatar

Is there a provider or recommended a brand of DMSO? I'm finding so many on Amazon and in the comments I see comments that say it's not pure since it does not solidify in the refrigerator. I have 8 herniated discs and unfortunately I reluctantly had surgery two weeks ago on my L5/S1 where the herniation had calcified. i had lost use of my right leg and the nerve pain was so severe I felt I had no other choice. I have 5 herniations in my neck which I would like to try the DSMO solution. Thank you in advance from NY

A Midwestern Doctor's avatar

There are three brands I can vouch for, the three I linked to. The amazon ones are faster to get and cheaper, the jacob lab one is the most likely to guaranteed to be pure but costs more and will take a bit longer to get. I've never personally used it.

Anne in NY's avatar

Thank you so very much and for all you are doing. I’ll order and report back on my progress

Anne in NY's avatar

Thank you so much for quick response. Can you point me to the article which has your recommendations. With the neck pain I’m having trouble looking down reading thru each article. 🙏

A Midwestern Doctor's avatar

It's in the bottom of this one.

Anne in NY's avatar

FYI. I ordered directly from Jacob’s and got both the gel and liquid in just 3 days. I also purchased the organic cotton clothes that can be found on Amazon for castor oil packs. I’ve been putting the gel onto the organic cotton clothes and wrapping the cloth around my neck at bedtime. I’ve experienced some relief in my neck which has 5 herniated discs Have been wrapping another around my right foot which is numb/weak post “L5/S1” surgery have some feeling back in my big toe. Thank you again for all that you are doing.

Clay's avatar

I have constant tinnitus and saw a reference to treatment in your post. Can you provide any treatment specifics as to topical, oral, etc.? Thank you, MWD

A Midwestern Doctor's avatar

That will be in an upcoming article.

This Woman's Reality's avatar

This may have been addressed previously, so my apologies if this is repetitious.

There is mention in these articles about using DMSO for tinnitus. I have had chronic, lifelong tinnitus since sustaining a crushed skull after being run over by a car when I was 2 years old. I am now 72 and the tinnitus is worse than ever. If anyone has any advice about topical or internal use of DMSO for this condition, I would appreciate the information. Thank you. (And, yes, I'm grateful to be still alive after all these years!)

This Woman's Reality's avatar

Thank you so very much. My boundless gratitude goes out to you for all the time, effort and expertise you share.

Dennis N's avatar

I love your information, Doc! AS a chiropractor since '83, I learned of DMSO forever ago but never used it. As I age with lots of aches and pains I have started using it in combination with CBD oil topically with good benefits. My question though is...I had an ischemic stroke in 2018, sensory not motor that still plaques me with occasional flare ups of left body numbness. You mentioned IV administration of DMSO and where would I even go to find somebody to do that (Tennessee). Im glad I became a subscriber...keep up the phenomenal work!

A Midwestern Doctor's avatar

Have to find someone through word of mouth. I believe there are more people doing it in FL than anywhere else.

J Boss's avatar

I came late to the party (for this "episode"), so forgive me if I'm asking a question already buried in the 300+ comments: At 61, I'm still very active in sports and the aches are greater for a day or two after. So I'm thinking I could use DMSO for the joints and muscles to aid recovery, plus the biannual tennis/pickel ball court tumbles I seem to always have).

If that's a reasonable idea, do I need to seek a prescription, or are one of the many "99.9% pure non-medical" DMSO products available "safe and effective" (but in the real way, not the COVID jab way)?

Thanks for highlighting DMSO. I read about it at least a decade ago with an intent to dig deeper, but I lost it in my electronic PDF stash and hadn't stumbled into it since.

J Boss's avatar

I am struggling with what format of DMSO is best and how to apply it for relatively minor issues, and even where to buy it. My most common issues would be joint pain in my hand and fingers (from decades of computer work, car and home repair, even sports) and muscle strains from sports, outdoor work, and "I'm old and slept wrong on my dadgum shoulder!"

Any advice on creme versus oil, application techniques, and maybe a good DMSO ailment applications book?

Apologies if I'm asking redundant questions. If those answers are here in the comments, just let me know to look. I don't mind the effort if it doesn't come up empty... lol

Thanks!

J Boss's avatar

I couldn't help myself, started looking at comments. This reply to the most popular comment seems like a good place to start with my questions above...

Discusses diluted oil on shoulder pain that sounds similar to mine. Perhaps I just need to read the comments, take some notes.

A workbook or "if this, do that" type of minor-ailment guide seems it could be helpful. Perhaps if it doesn't exist, I will create it for critique. A little scary of an idea (for sharing) from an engineer. I reverse engineer a lot for myself, but my studies are almost all an N of 1...

https://open.substack.com/pub/amidwesterndoctor/p/dmso-is-a-miraculous-therapy-for?r=nz0zc&utm_campaign=comment-list-share-cta&utm_medium=web&comments=true&commentId=72760724

Garhett Rittenhouse's avatar

He also provides the dosage and recommendations in the articles.

yantra's avatar

Thanks MWD. Just thought i should report - after some very limited DMSO external application on my body (not head), i started noticing a weird headache developing approx 8 to 12 hours later and persisting for many hours. This has happened in at least 2 or 3 instances, perhaps more, since with the first few uses i did not connect it to the DMSO. I quit using it and the headaches stopped. Not a terrible sharp headache, but uncomfortable nonetheless. Has anyone else you know of reported this?

A Midwestern Doctor's avatar

My guess would be the dose was too high for you and it triggered a mast cell response, which either means you need a much lower dose or your system is too sensitive for it.

BK's avatar

As an FYI, you may lower the dose in several ways. Either use the same amount in a lower concentration, or use the same concentration but apply it to a smaller area.

The goal is always to use the smallest effective dose, because it is always a risk versus benefit analysis that must be done.

Good luck!

Walt's avatar

I was just wondering .. if nothing adverse arises after testing DMSO at 100%, does it matter if one uses it at 100% vs a 70% solution .. ie is there a 'bell curve' where benefits increase with %-age up to a point .. eg a 70% solution .. and then decrease after that point?? Or is there basically no difference in benefits [since DMSO is easily available at 100% but not too easily bought at 70%, so one needs to dilute it]

A Midwestern Doctor's avatar

Some people's skin reacts to 100% but not 70% and 70% is normally strong enough to be effective.

J Pattison's avatar

Would DMSO interfere with the High dose Ivermectin and FebBen that my brother is taking to fight his cancer? He has painful lesions in his bones, so I would love to recommend this, but I don't want it to counteract his treatment. But I also wonder if DMSO could help with the absorption of the other drugs.

BK's avatar

DMSO increases the topical (through the skin) absorption of drugs, but to my knowledge, has no effect on the absorption of drug via the GI tract (stomach/intestines).

TJOL's avatar

How frequently does the garlic smell occur for DMSO users? Do 100% who use it get the smell - 50% - or any other %? Is there anything that decreases this smell reaction? How long after a treatment does the smell go away? Thanks for anyone's help.

Ned B.'s avatar

I've been using 99.995% pure DMSO from the DMSO store for three months now, every day, topically on my low back injury with no smell. With the ultra-pure formulation, very few people will get the smell reaction (which comes from DMS impurities in the less pure brands).

I get mine from Amazon: https://www.amazon.com/DMSO-Bottle-99-995-Dimethyl-Sulfoxide/dp/B01BSYQ0XC/

Garhett Rittenhouse's avatar

I use the same brand (same link :-) and I smell. Right from the first time applying topically, I smell like garlic and onions. MWD suggested some other supplement can help mitigate the smell, I think chlorine dioxin but I have to find it again. Now, I take orally as well and really smell :-)) Must depend on the person.

J T's avatar
4 janv.Edited

I read taking 1/2 tsp to 1 tsp of MSM every 12 hours while using DMSO will eliminate garlic smell. I use NOW Foods powdered MSM stirred into water - it's tasteless.

Garhett Rittenhouse's avatar

Did it work for you? Or, are you a non-smeller? :-)

DMSO ended up not being able to overcome my RA (worked for about six weeks, then I had such a bad flare up I started on prednisone again). I also was using enough DMSO I seemed to get petechia on my toes. I mentioned it on my other posts and MWD suggested I cut back (and with the prednisone...I decided to stop for now).

If I kick up the DMSO again...I'll try it with MSM. I currently have one of the books he recommended ("The Miracle of MSM: The Natural Solution for Pain" by Stanley Jacob MD, Ronald Lawrence MD, and Martin Zucker). I starts off similar to MWD so it'll be cool to see if MSM mitigates the smell of DMSO.

J T's avatar

I've been using DMSO only topically for a week, since I rolled my ankle. Haven't tried DMSO internally yet, waiting to see my reactions. I live alone and don't socialize much lately, so no feedback on whether I smell.

I got Andreas Kalcker's MMS book 'Forbidden Health' on ebay https://www.ebay.com/itm/356082579043, bought MMS but haven't tried it yet. I'll try them separately to observe results, then combine, so I know what helps and what doesn't. Used Aloe Vera gel to sooth slight skin irritation after using DMSO. I look forward to hearing how you do with MMS, and if it helps DMSO odor! Thanks!!

VictorDianne Watson's avatar

Thank you, AMD, for spending so much time on researching this most beneficial drug and reporting on its uses. After the first part of the series, I immediately bought it on Amazon as you suggested. I then eagerly awaited this part of the series so that I could discover how to use it to treat my issues. I am starting its use today and I will report on my reactions. Btw, I’m telling family and friends.

Dana's avatar

This is fascinating information. How would you suggest applying it for edema? I have had lymphedema since my 20's and often have swollen ankles. [I am not obese] This runs in my family and is hereditary.

WendeAnne's avatar

Best reading on Substack, in my opinion. I have lumbar spinal issues, scoliosis, and hx of trigeminal neuralgia unresolved by a MVD. I started DMSO today, I’m retired from Pharmacy and I’m fascinated and remember a scant amount of information years ago! I wish I knew all of this years ago! I’ve been through Hell! I hope DMSO helps! I’m optimistic. Thank you. You are awesome. 👏

J T's avatar

My unbearable trigeminal neuralgia pain disappeared in 1-2 days, by taking a homeopathic remedy recommended on ABCHomeopathy.com: either Spigelia anthelma for Left-side pain, or Mag-phos for Right-side pain. A neurologist had prescribed anti-seizure drug, but I learned it stops working, so eventually people get surgery to cut the trigeminal nerve, but nerve eventually grow back and terrible pain returns. I never took the Rx, found homeopathic cure - pain miraculously gone within days.

La loca's avatar

How did you dose/administer the homeopathic?

J T's avatar

La Loca - I followed instructions suggested here: https://abchomeopathy.com/forum2.php/96241#97172

Richo's avatar

I have developed a new use for DMSO. It is in regard to Pruritus Calcaneus, a bacterial infection that can penetrate deep into the heel bone. It causes extremely intense itching that comes from inside the heel, not on the skin, and is resistant to most any other treatment. I developed this some time ago and it can be excruciating.

This web site goes into the details. https://www.digitalwelt.org/en/lifestyle/herbs/deep-heel-itching

They recommend Tee Tree oil, but I developed my own protocol that I think works better.

It involves using a 50/50 mixture of DMSO and Hibiclens. Hibiclens is a liquid topical antibiotic, available otc. I keep it in a dropper bottle and apply it manually any time I feel the itch coming on. It works reliably within 5 or 10 minutes. It has no smell, and does not seem to require any callus removal or cover.

A Midwestern Doctor's avatar

Probably would work better and be safer to do with HOCl

Gary Morgan's avatar

After reading both DMSO articles (which finally made me become a paid subscriber), I'm going to give it a try for a damaged nerve in my leg (L5S1 disc degenerated and damaged the nerve before I had lumbar fusion). I also have had chronic pain for decades, which after many, many, MANY tests they slapped the fibromyalgia label on, though I'm not convinced that is correct. The garlic odor problem kinda concerns me, are there any suggestions as to ways to minimize the smell? Thank you!

yantra's avatar

i have recently tried the low odor 99+% pure DMSO, brand DMSOstore from amazon, It has very little smell upon opening the bottle and very little after use - as far as i can tell.

Anna's avatar

My husband has damaged nerves in his leg and foot from a surgery 2 months ago. He has been in excruciating pain every day since and has tried different pain relief approaches to help relieve the pain and burning (those mostly didn't work). He has been using the DMSO 70/30 with aloe (little odour) for the last 3 days and has finally found some relief..it's like a miracle actually. Thank you so much MWD!! You mentioned in a previous comment that you are working on DMSO eye applications which is interesting b/c my vision is getting worse lately. I am looking forward to learning more as I have heard that castor oil can be helpful, but am skeptical. Thanks again and all the best!!

Jacqueline Bernard's avatar

Absolutely fabulous. I’ve taken a lot of notes and I plan on sharing with my friends. Also, I’ve done some DMSO shopping on Amazon.

Deplorable MacBee's avatar

Thank you for all of your great articles. A lot went into the DMSO articles and they are very interesting and helpful. Love reading your substack.

Leland Stillman, MD's avatar

What about MSM? I have been using this in my practice for years and am curious if you think DMSO is for any particular reason superior to it, or if MSM is just as good as DMSO in clinical practice.

A Midwestern Doctor's avatar

I think DMSO does more, but it often works well to use both together and MSM unlike DMSO doesn't have issues such as odor and skin irritation. At some point I will try to do a piece on MSM but it will be a while before I get to it.

Garhett Rittenhouse's avatar

Looking forward to it...cause I stink :-)))

Jessie's avatar

Thank you for this article! I have the following question:

My husband had a stroke due to a vertebral artery dissection (the artery was torn by a chiropractic manipulation), and he has a stent in his vertebral artery. Is topical DMSO safe for him?

A Midwestern Doctor's avatar

Yes. Also I have run into a surprising number of people that happened to... (although none were treated with DMSO)

Ellen (Queen Bohemia)'s avatar

Also how would you apply DMSO for fibromyalgia? TYIA

Ellen (Queen Bohemia)'s avatar

Thank you so much for all your research and writing!! Question: how would you go about administering DMSO for tinnitus? Thank you in advance!

Robert Hunter's avatar

I've been thinking about a paid subscription for some time. DSMO which I've known about and used for some time for muscle pain, by itself or as a carrier for meds. It'll take some time to absorb the Post as it does with all your posts. Thanks, Robert! How did we get to needing to be anonymous to speak the truth especially in the US with the 1st amendment?

erin's avatar

A small critical contribution: I object to the repeated stress on how opiates kill people en masse. Not true! If used appropriately, they have only two major disadvantages; they cause constipation, and can be habituating (though less likely if used for pain). They do kill in overdose, but so does aspirin. So does water. The poppy is as much a healing gift from above as is the DMSO from trees. :-)

Cammy B MD's avatar

Thank you! I have had a big bottle of this and didn’t really know what to do with it or how to dose it. So thank you !

Cristina7's avatar

Amazing! 🤗

Thank you so much!

Arabella's avatar

This is wonderful. A true gift to the world. Thank you so much.

Is there much information available about DMSO and Alzheimers/dementia? How about autism? Where would the best (theoretically speaking of course) place on the body to apply this topically to get it to the brain?

A Midwestern Doctor's avatar

Everything I could find is in part 1

Deni's avatar

Hello Singing In The Dark

I am also dealing with thyroid issues

Can you share the name of doctor you are using to help with your DMSO/iodine protocol please?

Thank you!

Deni

A Midwestern Doctor's avatar

You should reply to her comment or she won't see yours.

Deni's avatar

Thank you dear doctor

karen h's avatar

Thank you for this wondrous series! I have controlled my RA with diet for the past 7 years when I was diagnosed. My right hand is most affected, with all digits bent. How long should I soak my hand in the dmso? Thank you!

Liz Medearis's avatar

Incredible article, and an amazing gift for humanity. This information will help so many people. For tinnitus, what is the best application for DMSO? Is there more than one? Deepest gratitude...

A Midwestern Doctor's avatar

Will write more on this later in the series, but this is a direct link to the paper I found that in.

https://sci-hub.se/https://nyaspubs.onlinelibrary.wiley.com/doi/abs/10.1111/j.1749-6632.1975.tb25389.x

Roger Boyd's avatar

Why wouldn't DMSO be researched and widely used in countries such as China where the US establishment does not have the same kind of control?

A Midwestern Doctor's avatar

I will try to explain in a later part of this series. I think it was still somewhat used there, I just haven't been able to find the papers.

A Midwestern Doctor's avatar

I provided links to Amazon products. Many others exist too.

Rex Hughes's avatar

That must have been after I started skimming.

Olivia's avatar

Is there a book, articles outlining exactly how to use DMSO for different situations? How to mix, quantity, how long to use, DMSO %, etc.? Always great information but lacking the protocol of exactly how to use --- especially internally.

Dorlis Lee Grote's avatar

Since being introduced to DMSO last year , at age 84 by a fellow Mercola follower, it is fast becoming my go to for healing everything including an area radiated in 2000 because lymphomas on my leg so close to the bone, the doctor feared the bone marrow would be "infected". It has never completely healed, always bleeding, healing, bleeding, healing. I started putting the gel on that area. It is now almost completley healed, skin color has returned to normal and circulation is now almost normal, my foot does not swell from lack of circulation. Actually I have found many so called folk medicines from the past are in fact superior to "modern" medicine. When I had terminal lymphoma in 2000, given 3 months by one of the top 4 lymphologists in the country, I first prayed for wisdom from God and healing, then organic, no processed foods, sugar. By the end of 2001, I was in remission! Then in complete remission! No manufactured , expensive medications from th pharmaceutical companies, just eating organic. I also lowered my blood sugar (type 2 diabetic) from 585 to now AiC of 5.7. I have not been to a dentist in over 10 years, no problems. Now for instuctions to use DMSO for tinintitus to get rid of that and I might make it to 94.

A very curious mind's avatar

is DMSO helpful for poikiloderma of civatte?

BlueHorse's avatar

Absolutely remarkable. You are treasured. Thank you.

B Notable's avatar

First, let me applaud and thank you MWD, for your detailed and thorough articles on DMSO. I'm a 64 yo man with advanced emphysema, decades old cervical and lumbar spine injuries with disc degeneration, arthritis and bone spurs, advanced osteoarthritis in nearly all joints of my body and various other more minor issues. This therapy has been life-changing! It has ended my heavy dependency on prescription(and non) NSAIDS overnight! I do have a question if you or any knowledgeable readers here wouldn't mind chiming in. I started the DMSO protocol a week ago now and have settled on a three teaspoon per day total dose, taken orally, split equally morning and night and cut to 20%-ish. Also, 70% DMSO applied topically 3x per day to my problem joints(cervical C3-C5, lumbar L3-L5, hips, ankles, shoulders, elbows, wrists and fingers. Starting at day 6, I have noticed my pain level in most joints increase noticeably and the joints are already behaving... "differently". By differently, I mean the pain type is different than has been normal for many years and some joints have become noisier, my jaw most noticeably(TMJ), but knees, shoulders and hips as well. I would say they are behaving as they did, maybe, 20 years ago. Has anyone else experienced anything like this? Does anyone have any idea why this is happening? Should I be raising or lowering the dose or just ride through it? Thank you much for reading and any thoughts you're willing to share!

Ian Campbell's avatar

This is the first reference I have found to DMSO being taken orally. It seems to me that this should be the most convenient way to deal with a difficult to apply substance for multiple body parts! especially as the gel doesn't dry quickly. We cannot get a roll-on here in the UK which seems the next best method and I don't trust DIY! US providers don't like sending DMSO products overseas it seems.

Can you confirm that is what you are doing and that my understanding is that you take an oral mixture with c 20% DMSO and 80% water. Do you use distilled or simply bottled/tap water? Any problems with taking it internally? I would be grateful for a reply if you are advised by Substack of my comment.

B Notable's avatar

Hello, Ian,

Yes, I can confirm I take three teaspoons of 100% DMSO, diluted in whatever fruit drink I have on hand in the moment, orally each day. Honestly, lately, I've been diluting it with Gatorade because it was on hand, lol. I dont exactly measure the dilution, and I'm sure it's diluted far lower than 20%. It has a rather off-putting taste unless well diluted! The 3 teaspoons total dose per day that I take is split in two 1.5tsp doses, each diluted in a glass of probably about 4oz of juice, then taken morning and night 12 hours apart. This is what I have found works best for me at this point in time. When I first started taking DMSO orally, I started at a lower dose of 1/2 teaspoon twice a day, always diluted to at most 20% DMSO, for a total of 1 tsp 100% DMSO per day. I continued that for a few days to see how well I tolerated it. Then, I moved up in increasingly stronger doses to find the lowest dose that relieved my pain to a tolerable level. I found that to currently be 1.5 teaspoons, diluted, taken orally twice a day.

I use the above protocol every day without fail along with diluting 100% DMSO to a 70% solution: 70ml of 100% DMSO TO 30 ml of potable aloe vera, with potable aloe-vera just meaning it is 99.8% pure aloe vera sold pre-thinned to a near watery consistency. Once diluted to 70%, I fill a 2oz, fine atomizing, glass spray bottle and spray directly on the most painful joints(hips, knees, spine, shoulders, wrists and/or fingers) then rub it in just a bit. I do that as much as four times, or as little as once, per day. It all just depends on my level of pain that day. The solution dries fairly quickly, about ten minutes or so. There have also been times, while in a rush, I have been known to just dip a clean finger in the 70% solution and rub it on a joint that's flared up a bit more than usual, usually my hip. Again, it dries fairly fast. There have also been times when I've run out of aloe, and I have diluted the 100% DMSO to 70% with just plain old distilled water(not tap!), and that also works fine and dries pretty fast. Whether spray bottle or finger, aloe or water diluted, all these topical methods have worked well for me as a quick localized pain reliever that can last for hours. I have found that using the oral and topical protocols has eliminated my need for NSAID pain relievers entirely! I hope I have helped with your understanding of how I dose and use DMSO. My strongest recommendation for dosing and using DMSO is to do lots of research(as you're clearly doing), but also, and just as importantly, let your body be your guide! Listen to your body if it's telling you it doesn't like something and lower the dose or dilute it more or use less frequently. I think over time, your body will acclimate to a dose you find that gives the greatest relief and healing qualities! Feel free to ask any questions. Best of luck to you, mate!

P.S. I've found A Midwestern Doctor's dosing and protocols along with a vast more fortune in information is available with a subscription to his Substack! Reading his posts has been a game changer for me and my health, and well more than worth the few dollars(or quid) cost per month! In fact, it is priceless when compared with the drivel from my own, pharma line toeing yes man(or woman), legal drug peddling, Primary Care Physician! \end of rant ;-)

Cheers, Brian

Expand full comment
Ian Campbell's avatar

Thank you very much for that. I can give it a try. I am not as bad as you sound. I am 70 yo but have had corroded disks - L3 & 4 for nearly 40 years as a result of a R knee injury at 15 playing rugby. But now I have the other knee giving up after the damaged one was eventually replaced when I was 62. Now my sacrum is stiff and eternally sore after 5 months on steroids (for colitis) last year which sheltered the pain. But I then drove alot while recovering and that damaged my back alot. Am awaiting MRI results, which in our useless NHS take forever to get through. So I am seeking the miracle to not lose mobility faster than I already am.

Very best, Ian

Rollo's avatar

Here goes a long shot but, do have you any experience or knowledge about dmso regarding chronic insomnia?

Its great to have someone like yourself reawaken awareness of DMSO. I had wondered what had happened to it after decades of it being absent from public discourse

Dusty's avatar

Is there a contraindication for using DMSO while taking Ivermectin (for example, could DMSO cause IVM to cross the blood brain barrier?).

Michael Mangold's avatar

I love DMSO and have been using it since my bodybuilding days in the 1990s.

I was diagnosed with severe osteoarthritis in my right knee and wrist, and moderate OA in my left knee and wrist in 2021. My orthopod at the time wanted to remove 3 carpal bones in my right wrist, do a full arthroplasty of my right knee, and a partial arthroplasty in my left knee. Since the diagnoses, I have used a mixture of DMSO and Castor Bean Oil applied topically to all affected areas daily, and am still moving around with only minor pain, walking at least 2 hours every day, and typing and writing like crazy.

Jeffrey Robert M's avatar

I used DMSO 45 years ago, playing professional baseball, for a pulled groin. What would normally take at least a week to heal, was reduced to two days.

I see DMSO has resurfaced!

I have low functioning kidneys, but stable, does DMSO help?

RingmasteroftheSShow's avatar

I have a grandbaby with moderate to severe eczema ( especially on her cheeks and ankles). We are up north, very cold winter, and her cheeks are just a step or two away from actually splitting open…..very red and cracked, nothing else works topically, and she of course is teething so her cheeks stay wet. Was going to talk to her parents about using a 25% liquid spray solution, but where is a good location to patch test on an infant, and would it be ok to patch test an infant? She is 8 months old.

Luke's avatar

I bought some 99.9% low odor dmso on Amazon. It's the Heiltropfen brand. Smells like garlic, tastes like garlic. I've been putting a teaspoon in about 4oz of water and drinking it. Also putting 99.9% on my neck with no irritation. I don't notice much effect from it and I don't smell bad. I only did this for two days. Is low odor dmso different somehow?

Michael Michailidis's avatar

Wondering where to find some guidance for oral DMSO consumption? Amount? Frequency? Dilution? Best “fluids” to dilute with. My wife has significant hip arthritis and pain, and topical application has its limitations. Thank you, Michael

A Midwestern Doctor's avatar

That is in the DMSO for strokes article.

Zade's avatar

I just applied some DMSO to my neck. I've had severe pain from a compressed spinal nerve at C3-C4 for the past 3 years. It's daily pain that sets in after I get up, is aggravated by looking at my phone or even a book. I bought a pure DMSO off Amazon, a liquid above 65 F. I applied it to a cotton ball and rubbed it where it hurts after I got up for the day.

The sharp and achy pain I usually get right after arising hasn't set in yet. Slight burning where I rubbed it has dissipated. I tend to have bad reactions to most meds so I'm cautious with this. But I'll let you know.

My goal is to get off the stinking opiate pain meds that don't really touch this pain anyway!

Marti Caskey's avatar

When you say to take MSM with DMSO for arthritis, do you mean orally or topically. I am planning on ordering the Jacob's DMSO to apply topically for arthritis and want to ensure I am doing all I can. Thank you.

liam's avatar

Hey Doc, Do you have an opinion on MMS (Chlorine Dioxide) ? Ive been reading about it and it seems like an alternative or even a good pair with DMSO. Ever heard of Andreas Kalcker?

Debbie's avatar

Do you know any dmso/vit c iv protocols

Mark Vatuone's avatar

QUESTION: How do you eliminate the garlic smell on the breath of someone who orally takes DMSO? My poor wife is suffering.

A Midwestern Doctor's avatar

Will cover in a later article.

Francine Locke's avatar

New here, amazed at the potential benefits, I just started for lower back pain.

You mentioned an improvement in eyes; vision, AMD, and Cataracts. Would love more info, specifically the dosing and version to purchase. Any benefits mentioned regarding a ruptured capsule?

Also, I've a few friends with MS, how would they proceed? Topical application, oral, IV? They are in the NW suburbs of Chicago, any recommendations for expert guidance?

Thank you so very much!

A Midwestern Doctor's avatar

A few people found it helped vitreous detachments, so it might help there.

I covered MS here:

https://www.midwesterndoctor.com/p/how-dmso-treats-incurable-autoimmune

Charlie Hotel's avatar

Hi AMD, I live way down under in NZ & wanted to know which brand is best for Knee & Ankle Arthritis? I also have swelling, heat, stinging, in my right lower leg & tingly numbness in the feet from Type 2 Diabetes. Can you tell me which brand to use & how much DMSO ratio to Magnesium oil, & how to apply & how often? Thanks so much for your wonderful work. 🙏

A Midwestern Doctor's avatar

I listed all that information in the bottom of this article. Mixing with other substances will be later in this series.

vie robs's avatar

I am new to this product, but have been diagnosed with arthritis in both thumbs due to age:) When dabbing on, what are you using, cotton balls, I did not read what to use. I also have tinitus in one ear, I was told to read an article by Dr. Mercola on using DMSO. How would I apply to the ear area?

Sam Miller's avatar

In regards to safety of DMSO for children this study worries me https://pmc.ncbi.nlm.nih.gov/articles/PMC2682536/ does anyone have any info to prove its safe for young children

A Midwestern Doctor's avatar

Has never been observed in humans. Conversely, many developementally disabled children have taken DMSO and had profound improvements in their neurological function.

Susan G's avatar

Hi all, so great to hear about improvements with DMSO. My husband is a veterinarian so he remembers people using it for horses. I got some from Jacob's Lab and I'm not sure how it apply it to my knee. I've had a bad osteoarthritis flareup. MWD mentioned using a paint brush to apply but I'm nervous it might have chemicals or contaminates (unless it's animal hair). I could use an organic cotton ball. If you get it on your hands, do you just wash off? These may seem like silly details but I would like to see good results and not make a huge mess.. Lol. There doesn't seem to be a lot of instruction out there. Thanks!

A Midwestern Doctor's avatar

All of that is correct. You can just wash off hands.

Susan Cundiff's avatar

Dosing ? Please! I bought Nature’s Gift 70% DMSO liquid and a natural brush to put it on my back. Since it was already diluted i did not do anything more. (i had used a 70% DMSO aloe Vera gel product previously without issue but it’s no longer available). When the liquid was put on my back it burned like HECK. Help…i believe in DMSO but i need some suggestions for how to handle this burning when using it?

A Midwestern Doctor's avatar

That's in the bottom of this article. You have to dillute the liquid enough that it doesn't burn, but in time the tolerance builds up.

Monica Frohmann's avatar

Thank you so much for your excellent and informative articles. We had horses when I was young and DMSO was always used to manage arthritic pain in our older herd members with great success. Now as an adult and homeopath of 25 years I see the benefits in all the areas you write about. Currently I have a 50 year old patient with arthritis-crippled fingers who had been responding well to a homeopathic remedy but when I added DMSO cream, was suddenly completely pain free. I am about to test it with an 86 year old man with macular degeneration and am very excited to see how he responds. I have liberally shared the DMSO articles as well as the extremely useful one on the history of vaccination.

I am wondering how concerned I should be when using DMSO on someone who has recently had a tattoo. I don't mean directly on the freshly tattooed skin but generally. Any insight would be greatly appreciated.

Monica Frohmann's avatar

Thank you for your reply. Only new ones or older ones as well? If it’s not to be applied even around older tattoos I guess that will be very limiting for certain individuals.

A Midwestern Doctor's avatar

It's probably not a good idea around older ones either.

BEFisher525's avatar

This morning. I awoke. With NO pain.

Thank you - thank you thank you.

I always wondered about those who claimed to perform household tasks in the buff. I guess they were just waiting for the DMSO to dry!

PS how long must one wait to use any (simple, pure ingredient) lotion on the skin??

❤️

A Midwestern Doctor's avatar

Once it's dried you can wash off the area, but if you want to give an hour longer to be safe, that's probably better.

TA's avatar

Perhaps someone else has asked this question, but I am wondering about frequency of use My issue is musculoskeletal pain - connective tissue strains. Do people do it whenever they feel pain or is there a recommended regiment? Thank you

A Midwestern Doctor's avatar

It completely varies, but for acute injuries, a few times a day until it's better.

Richard Poore's avatar

My mom is suffering from arthritis, she is desparate for relief, she is on a blood thinner(warfarin) she has a titanium heart valve, anyone know the dangers using DMSO?

Dennis N's avatar

Question for MWD or group...has anybody had an experience of DMSO (or methylene blue) lowering cholesterol numbers and reversing plaquing in the carotid arteries? (Im not saying one causes the other). Thank y'all

sue's avatar

Cholesterol doesn't cause plaque. Many books and videos about that hoax. Start with MWD's article on it.

Patricia Casteels's avatar

Healthy 60 year old… I am just out of a breast explant surgery. Lots of pain and heavy bruising around the drain area and where the muscle was lifted to remove capsule and implant. I am tempted to apply DMSO topically but afraid of blood tinning because it is just 2 days post surgery. I strongly dislike the Percocet so I am in pain… I would love to hear anyone’s experience post surgery. Thanks !!!

sue's avatar

Usually they only worry about blood thinning for the surgery and say you can start back on supplements and drugs that thin blood the following day. I would think now is when you'd want it, to reduce the inflammation and bruising.

Unfortunately I didn't know about it when I had surgery for cancer, maybe it would have prevented some of the numbness that occured. But I used it recently after a tooth extraction and it healed extremely fast.

Garhett Rittenhouse's avatar

in this article https://www.midwesterndoctor.com/p/dmso-is-a-miraculous-therapy-for

he lists it as one of the second or third bullets in the top:

•DMSO is a highly effective therapy for healing wounds and creating healthy scars, making it particularly helpful for recovering from surgery.

Al DuClur's avatar

Maybe I missed it in the article but how do you suggest using DSMO for hearing loss?

I have used, upon your suggestion, DSMO cream on my arthritic toe and it feels 80 percent better after only 3 treatments

Big E's avatar

Former Congressman and Newsmax Host Michael Grimm Left Paralyzed After Tragic Accident-Here’s How You Can Help. by Margaret Flavin Nov. 14, 2024: https://www.thegatewaypundit.com/2024/11/former-congressman-newsmax-host-michael-grimm-left-paralyzed/

Also, Newsmax article: https://www.newsmax.com/newsfront/michael-grimm-congress-paralyzed/2024/11/11/id/1187518/

Michael Grimm Facebook: https://www.facebook.com/MichaelGrimmNY/

Horse riding accident left Michael Grimm paralyzed from neck down. If anyone with medical training and/or anecdotal experience can contact the former congressman and talk with him and his doctors about the possibility of using DMSO (https://www.midwesterndoctor.com/p/dmso-is-a-miraculous-therapy-for/comments), perhaps his quality of life could be improved.

GoFundMe: https://www.gofundme.com/f/help-michael-grimm-walk-again

MrsRicoChavi's avatar

Are there concerns about applying DMSO over a tatoo?

Shel's avatar

I've been using it topically, but I think I'm going to have to stop or use it very sparingly spot treatment. Since I've been using it I have been getting frequent headaches and feeling super tired. It did seem to be helping to clear up some discoloration and skin patches that I've had for quite awhile, but I can't do the headaches and fatigue.

sue's avatar

I'm getting headaches on and off too and keep wondering if it's connected. But sometimes I get them and sometimes I don't, so I'm not sure. Last night I put on the most I have so far and I woke up feeling weirdly depressed and my lymph nodes painfully enlarged. I'll have to read the posts all again and see if potential side effects was discussed.

A Midwestern Doctor's avatar

My guess is that that's too high of a dose for you, so if you want to keep using it, you need to use a lower dose (e.g., a few drops in water) and to do it intermittently. Some people are more sensitive and these types of responses are typical for them with normal doses. One of my friends recently tried it, had a great response to 1 tsp, then realized it was too much, and switched to a few drops and found that was incredibly helpful for him. I want with the 1/2-1 tsp for oral because that's what most people find really helps them.

Shel's avatar

I backed off of using it and stopped waking up with the headaches and stopped feeling so weirdly tired, so I do think we've experienced a side effect. I did see some signs of possible healing/improvement with my skin, so I've taken to doing just a very little spot treatment. I don't think I will be using it orally.

A Midwestern Doctor's avatar

My guess is that that's too high of a dose for you, so if you want to keep using it, you need to use a lower dose (e.g., a few drops in water) and to do it intermittently. Some people are more sensitive and these types of responses are typical for them with normal doses. One of my friends recently tried it, had a great response to 1 tsp, then realized it was too much, and switched to a few drops and found that was incredibly helpful for him. I went with the 1/2-1 tsp for oral because that's what most people find really helps them, but there's no dose that fits everyone.

HeatherD's avatar

How often are you supposed to apply DMSO to the injured area (like shin splints)? Once a day? Twice a day? 3 times?

A Midwestern Doctor's avatar

It varies person to person, but normally 1-3 times a day.

Kendra McConnell Hurd's avatar

So how do you recommend I find someone who is a doctor or PA or RN who could help my 88 year old mom who has spinal stenosis, neuropathy in feet from diabetes and congestive heart failure and a super positive attitude but does not like opiates and has tried many things that don’t work.

HeatherD's avatar

How often are you supposed to apply DMSO to the injured area (like shin splints)? Once a day? Twice a day? 3 times?

A Midwestern Doctor's avatar

Significantly varies person to person. Could be any of those. Start with once and then decide if you want to do more.

Charles Mallea's avatar

Looking forward to your post on protocols!

Annie Mc's avatar

Does internal dmso help with stomach ache? Does anyone know?

Sam Miller's avatar

Was just wondering about giving it to a child because according to the below article it is toxic to the nervous system of children https://www.sciencedirect.com/science/article/abs/pii/S0969996108002830?via%3Dihub

John Newhouser's avatar

I have been reading these articles with great interest. I initially bought pure DMSO from the DMSO store. It came in a clear glass bottle. I have been using it on my injured shoulder. It does irritate the skin a bit but that is the only indication that it is doing anything. I understood it to have an odor, and this is odorless. I just received a bottle of 70% from Jacob's and it has a distinct odor. Interestingly it came in a plastic bottle. I'm going to try the Jacobs on my shoulder. Can anyone comment on the odor/odorless difference?

KEK's avatar

The dmsostore roll on 99% non diluted I use has no smell. I love these Rollins. We use it for so many things

sue's avatar

I got Jacob's in a glass bottle and if there's a smell it's very mild. There's definitely a taste though.

Sam's avatar

I have dmso cream that just smells antisepticky, kinda medically-smelling, not horrible at all...maybe the liquid will be smelly (waiting on order)

Rich's avatar

I would like to hear from readers where to buy DMSO (safe, quality, not made in China). I need some relief now and don't want to wait until the final part of this series of articles is published to find out. Thank you.

A Midwestern Doctor's avatar

The information is in the bottom of this article (and many other ones in the series)

Ryan Boulo's avatar

Great article. I appreciate the time you must have put into this. My wife just bought me some for use on sciatica. I will start with topical, but if I decide to ingest, what's the protocol there? I didn't see where you mentioned percentages and other tips for ingesting. Thanks a lot!

Annie Mc's avatar

I haven’t read every question and may be missing something within the vast body of knowledge you e shared with us, but can you tell me if you’ve addressed endometriosis? I have a friend in great pain recently told she has pcos and I’m doing some research to hopefully help her avoid the medical system. Any info would be great but I’d especially be interested to know if dmso has helped. I’m assuming it would based on this info… thank you so much AMD! You’re helping so many people and I’m so grateful.

A Midwestern Doctor's avatar

That was discussed in the most recent article.

Sam Miller's avatar

There is a case report of 3 women with endometriosis that took bladderwrack seaweed and their cycles regulated. https://pmc.ncbi.nlm.nih.gov/articles/PMC514561/

Ursula Gibson's avatar

Maybe this is a topic that has been addressed somewhere already but I’m concerned about reviews I’ve read warning of a very unpleasant odor when taking DMSO orally.

I just started to use DMSO for joint pain and would like to try and take it internally for a more generalized application but I’m very concerned about the possibility of an offending body odor.

Any thoughts/ suggestions/ experiences?

Gail's avatar

Hello ~ Thank you Midwestern Doctor for all your information and desire to get this valuable information out to “us”!

I was wondering if you could help me with dosing for my husband who has Parkinson’s. After reading some of your articles I am very interested in starting him on oral DMSO. One of my concerns is do I need to make any changes in his prescription Parkinson meds? I have received the DMSO 99.9% liquid from the DMSO Store.

I thought I’d start him out on ½ tsp in 8 oz. of apple juice following breakfast. I was using a 65/35

DMSO gel on his troublesome toe and he did not have any reaction to that application.

I have to admit that administering DMSO topically kind of scares me, and maybe I’m making too big of a deal out of it. I would like to apply it topical to his back since he has severe spinal stenosis and nerve impingement which is causing extreme and debilitating back pain. I’m just not sure how to proceed ~ full strength liquid or diluted or?

As a side note, in tow days he is scheduled for a tooth extractions due to resorption and I am wondering how DMSO would affect that outcome if started next week.

Any further help would be greatly appreciated!

Thank you so much for your work and all your help!

Have a fabulous day ~

Gail

sue's avatar

From what I've read and done, just put the 70% liquid on and keep it exposed (no shirt or anything touching it) until it dries.

Also I had a tooth extraction 3 weeks ago and alternated between ozone oil and dmso. It healed much faster than they said it would. I also went to a biodentist that cleans out with ozone and fills with prf so YMMV. But definitely make sure the dentist removes the periodontal ligament because many don't and it causes chronic inflammation and infection.

Roger's avatar

I may have missed this, and it may be impossible to answer specifically, but for chronic muscoloskeletal injuries--e.g. wrist tendon problems, partial shoulder labral tears, etc.--how many applications per day are recommended? In my case I'd be taking two days off per week as the doctor mentioned in one of his articles, but wondering about number of applications per day. Thanks for any reply.

Garhett Rittenhouse's avatar

I have a totally different issue but put it on my arthritis shoulder 3 times per day...started at 25% solution, then moved it to 50% (after about three days), now I use about 75% solution (when I get flare ups).

In some comments above, he recommended 1-3/day on shin splints.

KEK's avatar

We have a friend who has terrible throat scarring from radiation from throat cancer. He has to puree everything and it’s a struggle to get food down. How would you recommend he take dmso…any protocol suggestions? Also which brand and where to get it? Thank you.

A Midwestern Doctor's avatar

Oral, swallow very slowly, 1 tsp in glass of water.

KEK's avatar

I should have also asked about frequency…I.e. 1-2x daily…..etc ? Thank you so very much

KEK's avatar

He is going to start the dmso this week thank god. I found out that his neck is also being pulled into a sidebent posturing -apparently from the scarring continuing to grow he thinks. So if you see this- should he do the dmso slow swallows (1 tsp in a glass of water) several times a day?

yantra's avatar

i am posting this from Chelles: she wrote: "So sorry to comment on a thread, but there’s some glitch with substack and my (very old phone/computer) that only lets me comment on other comments 😅

"Reading the parts in this series about recovering tissues (sprains), rearranging proteins, and how it helps other musculoskeletal issues has me wondering about its potential with EDS patients? Have you come across anything that might support this?" . . . . . . . . . . . . . . . . .

. . . and yantra responded to Chelles with: 'good question - when MWD wrote': . . . "DMSO is often used to treat scars. This may be in part due to DMSO being observed to disrupt the links between collagen fibers" - 'i was wondering if that would mean it could accelerate or increase ligamentous laxity. I am going to post your Q and my comment as a new post so it will more likely be seen'.

Christine Horner's avatar

Thank you for noting that mixing it with distilled water that it will warm up. It did exactly that. I did pour into a small blue dropper glass bottle via a small plastic funnel. I'm concerned the plastic funnel is not a good idea? Yet, the distilled water has been sitting in a plastic jug. Excited to start using!

CW's avatar

Thank you so much for sharing your vast knowledge on this. I will be ordering and trying it on myself and my husband for various MS disorders. Do you have any information on how a lupus rash may react with DMSO? I saw that psoriasis can be worsened by it.

James Fambro's avatar

thank you for confirming that Natures Gift is a good brand. I have used this brand off and on since the early 2000's.

Daniel Warner's avatar

I 'm so glad, Dr. Midwestern, that you're providing all of this valuable and otherwise difficult to find information. I just recently started using DMSO both orally (one teaspoon of undiluted DMSO in some juice once a day) and topically using a 70% solution. Many people taste the DMSO in their mouths after topical application, but I never do. Does this mean my skin isn't absorbing it? The only time I taste it is when I take it orally, so naturally I'm going to taste it then. I'm hoping it will help my IBS get better along with a mild case of GERD. It's already removed pain in one of my shoulders and toe.

Ŵilliam Watson's avatar

How to find a Dr who will inject DMSO?

Garhett Rittenhouse's avatar

word of mouth...although in one of the comments he said FL has the most...but...i'm asking a doc in the area too. one that does UVI so he might know...

George's avatar

What would be really good is if you had a forum where people can discuss different ideas and recipes for healing.

Christine C's avatar

Great article - thank you for the hundreds of hours you have spent putting this together. Have you seen / experienced DMSO being used for Parkinson’s?

Flatulus Maximus's avatar

Another thing I'd be interested in hearing about (and wouldn't be surprised if you had something in the works!) is taking DMSO via nebulizer. My MD put me on nighttime oxygen several years ago, after I began experiencing a lot of daytime sleepiness. A sleep study revealed that my breathing became so shallow while asleep that I became a bit oxygen-deprived. Fast forward more than a decade, and I've been diagnosed with COPD. I'm on a remarkable medication (Trelegy Ellipta) which enables me to feel better and be reasonably active, but I was curious if DMSO could ease some of the lung inflammation that is a part of this disease. I use a humidifier attachment to the oxygen machine, and about a week ago I started adding 5 drops of 99.995% DMSO to the humidifier. It's too soon to judge the efficacy of this, but it certainly doesn't seem to be harming me any.

yantra's avatar

MWD wrote about dmso via nebulizer in one of these articles; it sounded like they gave it to monkeys(?) and it had bad effects.

sue's avatar

Thanks, I'll have to find and read that. I breathed it into my sinuses with steam, wonder if that's the same as nebulizing.

Flatulus Maximus's avatar

My wife mentioned that to me, too. I'll have to go back and read that again, but my sense is I'm using a very low dose--about 5 drops in an 8 oz. reservoir. If I recall correctly, the researchers were using higher concentrations. But I'll check.

Maura's avatar

From all I've read, thanks! I'm a believer (and in pain!) I signed up specifically to find out where to purchase, %age dmso for chronic ankle, nerve issue resulting from a car accident, where no doctors have yet to give me a solution. Where do I find reputable supplier? Tysm!

Chanda's avatar

Thank you for your time and research! This is the first time I’ve heard of DMSO and after reading this, ordered it for my knees. Hoping to regenerate some cushion in there!

Susan Cundiff's avatar

Thank you for sharing and caring! Not a frequent” commodity” seen or experienced today. Thank God there are still people like you. QUESTION: What kind/brand of DMSO would you recommend? (Something hopefully that will mitigate or lessen the odor side effect) AND, what would be the dosage for back pain (or any pain:? Taken orally or just topically?

A Midwestern Doctor's avatar

All of that is in the last part of the article.

People typically start with topical and then if needed go to oral.

David McDonald's avatar

Amazing series of articles on DMSO.

I have a question about patients that have mesh inserted for hernia repairs or bladder slings.

Would the DMSO dissolve the mesh?

A Midwestern Doctor's avatar

To the best of my knowledge no.

MaryAnnGrubbe's avatar

I have sciatica with unrelenting pain down my left leg into my knee and calf. Cause is undetermined by mri. Where would I apply the dmso?

A Midwestern Doctor's avatar

Low back to calf. Start with a small area and then figure out what area you need.

SQ's avatar

Thanks for this! Just curious, if DMSO can absorb bad things, like pesticides, into the body, can it help absorb beneficial things? And what would be a beneficial thing? I've used Manuka honey for small wounds and it works well.

A Midwestern Doctor's avatar

Yes it's often used for that; will cover later.

Deborah Mathieu's avatar

How do you contact this doctor? Or perhaps someone here can help me… I have suffered herniated discs and can barely move, the pain has been so unbearable. I have started on topical DMSO and it has helped immensely, but I need to do intravenous. I live in Mexico and the dr. Here used a 99.9% purse DMSO cutting it with saline to about 4% total. I had no reaction, but I hardly think 4% would be worth the effort. Here’s the issue, the day after the intravenous, the pain I had was intense; today I hardly feel any pain. I need guidance to get this right and I have a wonderful dr. here who will work with me (I will not do surgery.) Thank you for taking the time to read this, and for any help that can be offered.

beth02's avatar

Can anyone provide recommendation on an appropriate natural/organic brush applicator ?

A Midwestern Doctor's avatar

You just need to make sure the brush is made from hair.

Erin Reasoner's avatar

I have seen that the fda approved this for interstitial cystitis but I’m not sure they do now. I suffer this condition. I was hoping you could help me with dosing

A Midwestern Doctor's avatar

That is in the part I just published.

Erin Reasoner's avatar

I see that you take a tsp 1 to 2 tsp’s a day but do you know how long a person should take it or is it just a one dose therapy.

A Midwestern Doctor's avatar

it really varies, but it can often be for a while

Sara's avatar

Hi. Did you find the dosage and application method?

Annie Mc's avatar

Curious which kinds of scars are treatable with dmso.

Kenneth Griffith's avatar

I'm sold. But how do you figure out the proper dose and application method?

A Midwestern Doctor's avatar

I provided everything I know.

J Pattison's avatar

VERY IMPORTANT QUESTION: HOW LONG WOULD SOMEONE HAVE TO BE OFF NARCOTICS FOR CANCER PAIN BEFORE TRYING DMSO? Since the DMSO intensifies drugs, would someone have to be off of narcotics for a full 5 days (the length of time for it to get out of one's system)?

J Pattison's avatar

VERY IMPORTANT QUESTION: HOW LONG WOULD SOMEONE HAVE TO BE OFF NARCOTICS FOR CANCER PAIN BEFORE TRYING DMSO? Since the DMSO intensifies drugs, would someone have to be off of narcotics for a full 5 days (the length of time for it to get out of one's system)?

LCC's avatar

Would like to have a link to a reputable source to purchase DMSO. Can anyone provide such a link or suggest a product that is best to use for shoulder pain? Are the commercially available products such as those on Amazon effective? Also can anyone provide a protocol for use ?

A Midwestern Doctor's avatar

I linked to the ones we use.

Robyn G's avatar

I purchased the liquid product from the DMSO store. I know I need to dilute the product with purified water. How do I safely measure out some product to dilute? Should I get a glass pipette? If I spill some on my stainless steel sink, will it cause any problems? I like the idea of using a paint brush with natural fibers but how do I know which ones are safe and do not contain toxins? IDo you have a link to the paint brushes you use? Is it ok to put the product in a Pyrex bowl?

A Midwestern Doctor's avatar

You can use a steel measuring spoon. Won't cause issue if you drop in the sink. No issues with Pyrex. Don't have a link for the brush.

Ondine Constable's avatar

Are new comments being answered? I submitted a question a few days ago, wondering if DMSO could help with vulvadynia. Thanks

A Midwestern Doctor's avatar

I don't have time to answer every question. I thought I replied to you but basically:

•Will write about it in a future article.

•Vulvodynia is often due to oxylates.

Missy's avatar

Can anyone recommend a good brand of DSMO?

A Midwestern Doctor's avatar

Sorry if it was not clear from the post, but there are 3 brands:

Nature's Gift (longest selling brand besides Jacob Lab)

The DMSO Store (highest purity)

Jacob Lab (not on amazon)

Missy's avatar

Thank you so much! I can’t wait to try this!

Martin Fox's avatar

Lymphoma from breast cancer with significant arm swelling - can DMSO topically help? Thanks

Martin

A Midwestern Doctor's avatar

It can but not gaurenteed.

bammin's avatar

I am interested in hearing more about ultrasound directing dmso. I have an old lower back injury that might benefit from dmso, but most of it doesn’t seem to be at the surface.

A Midwestern Doctor's avatar

Basically you just put dmso between the probe and the skin and then direct it to your target, and the US pushes it through the skin to it.

bammin's avatar

I don’t recall if you talk about this, but is there any other material to pair well with dmso to carry to old soft tissue injuries?

Tina Blease's avatar

Daily usage: I’m in my 60’s and I have normal aches and pains. Could I simple add some drops of DMSO into my body lotion that I apply daily? If so, how many drops per once? If not, what would you recommend?

A Midwestern Doctor's avatar

I would not mix it with the lotion.

Tina Blease's avatar

do just dilute with water? I think you mentioned Aloe Vera oil. What about coconut oil? or simply just get the gel.

Garhett Rittenhouse's avatar

Some people (me included) diluted with castor oil (MWD didn't recommend so this was my experiment). Put it on hemorrhoids...it helped tremendously. Made me sick for a bit (hell...probably way too much DMSO to start). So, I'd go easy to start :-)

bammin's avatar

Let the doctor be the final word, but elsewhere he says that dmso will dissolve various compounds and draw them into the body. Might have a good or bad effect. I had a great experience with an injury by simply applying it in gel form liberally.

Tina Blease's avatar

I haven’t gone yo an allopathic doctor in 25 years. ND yes! And Chiro but neither of them knew about DMSO. I do all wellness diagnose on my own.

sue's avatar

Amazing. Could this be used during dental procedures where injectable anesthetics don't work great for me? Rub it on the gums?

A Midwestern Doctor's avatar

Will write about dental later.

Janice L. Blake's avatar

Will DMSO help stop seizures occurring after scarring from a brain bleed?

Will it make Alzheimer's go away? Will it make them talk again?

Libby R's avatar

Can DSMO be used to treat hypo or hyperthyroidism? Can it be dispensed through a compounding pharmacy?

A Midwestern Doctor's avatar

First one is kind of complicated, but it's not typically the default choice. It probably can be, but you can also just order it on amazon.

Brucetrost's avatar

Applied topically, is there any interaction with other medications, specifically INR levels? Thank you!

A Midwestern Doctor's avatar

Everything I know was covered in the article that was just sent out.

Ondine Constable's avatar

Could DMSO be helpful for vulvadynia and deeper vaginal pain? Any suggestions how to use it for this purpose?

A Midwestern Doctor's avatar

I do not know, however that is often due to excessive oxylates.

Greg's avatar

Would DMSO help shrink an enlarged prostate? I have 99% gel I applied to the perineum for a few days. No improvement yet. I enjoy your work.

A Midwestern Doctor's avatar

Will write about that in a future article.

Chris Jack's avatar

I have many metal rods in my legs due to a severe car accident. Are there any precautions I should be aware of with the metal. Will DMSO interact with the metal in any adverse way?

A Midwestern Doctor's avatar

Everything I know in that topic is in the article I just released.

Steve Mackinney's avatar

Tinnitus was mentioned in the article but no info on how to treat it with DMSO. I found a pubmed entry showing a study of 15 patients with 9 being cured and it mentioned spraying DMSO into their ears, but not what solution or how much or how often. Anyone have knowledge of this? Thanks

A Midwestern Doctor's avatar

I mentioned it in the comments, but you can view the study through https://sci-hub.se

Jonathan Smith's avatar

My wife is currently being treated for metastasised bowel cancer. To date, surgery was followed by iv chemotherapy. A scan at 6 months revealed that the oxaliplatin + capecitabine had failed to control the problem. For 3 years her condition remained stable, maintained by 35 cycles of Lonsurf. She has now started a cycle of Regorafenib as the Lonsurf ultimately failed. My question relates to drug interactions. I would like to try using DMSO to help with peripheral neuropathy in her feet (the result of the initial chemo). However, I have read that DMSO may potentiate the blood thinning medicine she also uses (Edoxaban 60mg daily). Is this a significant risk meaning DMSO could be problematic ? Any advice would be welcome.

A Midwestern Doctor's avatar

Everything I know on that topic is in the article I just released.

Jonathan Smith's avatar

Thank you for all the information you provide. I love science, and one of the most depressing aspects of the whole pandemic/lockdown/vaccination circus was witnessing the politicisation of the discipline. I now believe next to nothing which the state tells me and depend to a large degree on intelligent articles such as yours to inform me about health matters.

Roger's avatar

Extremely useful article, forgive me if this question has already been answered. Is the gel version of DMSO generally as effective as the liquid? Thanks for any reply

A Midwestern Doctor's avatar

I think the liquid is more effective but more of a hassle

Eric Roth's avatar

correction: "waist" is misspelled in the phrase "typically used below the waste (e.g., 60-80%)"

Philip Voyer's avatar

After reading your article, I am very interested in this product. I suffer from chronic arthritis and have had multiple surgeries on hands, arms, knees, shoulders and back. Can you recommend a site ( if you’re able) and strength for DMSO? Thank you.

Martha Sutherland's avatar

Thank you for your insights. Have you explored and written about any integrative therapies specifically related to neuro and muscular skeletal inflammation caused by Lyme’s and other tick borne diseases?

A Midwestern Doctor's avatar

Only a bit within the ultraviolet blood irradiation article.

Walt's avatar

Really terrific article and greatly greatly appreciated !! We will definitely try this out to help various issues !

I was wondering re arterial 'plug-ups' [eg cardiovascular issues for the heart, but also found elsewhere eg in the carotid arteries] .. I can't remember if this area was covered by itself.

Suppose one has carotid artery 'plug-ups' or 'plaque' [I think this is what its referred to] .. would brushing a 70% DMSO solution along this neck artery help dissipate this obstruction??

And if so, would it 'travel' elsewhere to help dissipate similar problems on other arteries.

Thanks -- Walt

A Midwestern Doctor's avatar

Normally we use EDTA for plaque.

Dan Star's avatar

Trying to find an applicator for my spine but concerned about DMSO dissolving it and absorbing toxic chemicals. Also interested in nebulizing DMSO for my chronic sinusitis. Any advice?

A Midwestern Doctor's avatar

All the authors advised not nebulizing DMSO. In the ENT part of this series I'll cover how it's used for the sinuses.

Aletheia Cyr's avatar

I'm reading through the comments but can't seem to find this question answered anywhere. Do you recommend a specific brand for the DMSO gel?

Aletheia Cyr's avatar

I'm also wondering, for my daughter who is 5 and has joint pain (we are working to heal her gut/immune system). Would you recommend topical or ingesting? Thank you so much for this info!

A Midwestern Doctor's avatar

start with topical. Joint pain may be a dietary allergy though.

Aletheia Cyr's avatar

sorry, I must have missed this liquid - which brand is it?

A Midwestern Doctor's avatar

They are listed at the bottom of both DMSO articles.

dodo's avatar

I got heiltropfen brand 99.9 pct dmso and made it around 95 percent. It has a slight smell but not strong. I feel the slightest tingling but don't get any welts at all and I am a partial ginger,y mom being ginger.

Shouldn't I see some side effects or is that often no indicator? Have used all around my body though not inside arm, albeit very close.

My wife did have some redness on her neck at around 50 percent.

Jacqueline's avatar

Please review this and address these positions.

https://open.substack.com/pub/medicinegirl/p/disastrous-dmso?r=r80st&utm_medium=ios

I have known about DMSO and have used it (although I haven’t found great improvement), but this article gave me pause. There are many positions of this author with which I agree.

A Midwestern Doctor's avatar

Her account of the history of DMSO is not at all accurate or congruent with the existing toxicology data.

Carol B's avatar

Wacko question. 🤔. Could it dissolve a cataract?

A Midwestern Doctor's avatar

Will go into the eye applications in the future!

Patricia Beaupre's avatar

I have been using DMSO.store 40% DMSO eye drops for cataracts for several months and have seen a noticeable improvement in my vision.

A Midwestern Doctor's avatar

Can I quote you in a future article?

Patricia Beaupre's avatar

Absolutely! Thank you for everything you do to help teach us how to take care of ourselves. I am 83 and have been responsible for my own health care without a doctor for almost 50 years. I’ve done a pretty good job but sometimes would like someone like you for a back up… sure wish you could be my doctor!

ReaderX's avatar

I hope you will go deep on cataract treatment. I have them and surgery appears to have nearly a 50% relapse rate (clouding of capsule requiring yag laser treatment) within 5 years. Because of this I've been using DMSO with Castor Oil drops 30/70 ratio respectively for about 5 weeks now. 1 drop in each eye 2x per day. While they have helped my dry eye symptoms so my eyes feel better, my vision continues to get worse. I can't recognize faces or read street signs that are backlit by the sun. Nor can I read tiny print. But in the absence of glare, I can read (white text on black screen is far easier than black text on white screen), colors are vibrant and the world is still beautiful. Despite my visual deficits (which perhaps bother me more because I used to have perfect vision) I still have a lot to lose if I make the wrong decision. It hard to know what to do.

Tzicken's avatar

Do you what type of cataract you have? Is the cataract on the front or the back of your lens? I been using the 40% dmso drops as well. I started one month ago but have yet to see any improvement. My cataract is at the back of my lens so I am wondering if the drops are even able to reach it.

Patricia Beaupre's avatar

Sorry, I’m not sure if my cataracts are on the front or the back. I didn’t notice much improvement at first but the improvement has been very gradual over a period of 4 months and is now very noticeable. Keep at it and I hope you notice improvement soon.

Tzicken's avatar

Thanks so much for your reply and the encouragement!

ReaderX's avatar

Mine are also at the back of my lenses. Perhaps this makes them harder for the DMSO to reach and do its magic.

Tzicken's avatar

Yes, perhaps it does...I finally ended up getting surgery on my right eye. After 8 months of trying to treat the PSC cataract with DMSO it was only getting worse. I was legally blind in my right eye and about to lose my job. I no longer had the "luxury" of trying to treat it on my own.

My left eye, however, is a different story. I have an early stage nuclear cataract in that eye which has slowly improved with DMSO use. My astigmatism in the left eye has improved as well. My new glasses prescription was milder than it's been in decades!

ReaderX's avatar

Thank you for the update. Are you happy with the results of the surgery? Mine are quite bad, and I fear I don't have the luxury of waiting either. I had an extensive exam two weeks ago, after 5 weeks of DMSO use. Aside from the cataracts everthing else they could see (blood vessel, cornea, tear film "looked healthy". What this tells me is that the DMSO hasn't hurt my eyes.

Tzicken's avatar

I am overall happy with the surgery. I've been dealing with fairly severe "dry eye" since, but it is certainly better than being blind in one eye. They had me using moisturizing eye drops 8 times a day for the dryness and when that didn't help, they gave me a corticosteroid eye drop. I was very hesitant to use this as I suspect a prescription steroid got me into this mess in the first place...

I have since found an excellent moisturizing eyedrop that I need apply only once or twice per day. I also use a castor oil eye drop at night.

I am sorry you are going through all of this as well...I wish you the best of luck if you get the surgery. If you find you have a problem with dry eye please let me know and I will post the link to the eye drops that, for me, are superior to those in the drug store.

ReaderX's avatar

I already have bad dry eye, which has caused me severe headaches. And also have a history of steroid drop use. This is one reason I am really afraid of the surgery. I would love it if you would share the link to the eye drops. Was there anything your doctor could have done differently to prevent the dry eye? I am curious as to whether or not you had laser assisted surgery, and which type of lens you got. I use DMSO/castor oil drops already, They help prevent the severe dry eye headaches, but my eyes are still red and irritated all the time (unless I use steriod drops). I was thinking I would need to discontinue DMSO after the surgery since its a solvent and the lens may be plastic of some sort. But it looks like MWD posted elsewhere that theres no evidence DMSO damages artificial lenses. Maybe I can ask the doc to give me an extra lens that I could soak in DMSO to see what happens to it :)

Tzicken's avatar

Thanks so much for your reply. It sounds like you have far more experience with dry eye than I do! I am truly sorry you are dealing with all of this...

You may already be familiar with the product I am using: https://barecatbody.com/products/moisturizing-eye-drops-hyaluronic-acid

When I first started these drops, they stung like mad. After a couple of weeks, the sting became much milder and my eyes are now FAR more comfortable. I use these twice a day.

I wasn't aware that DMSO could be used on an eye with an artificial lens! I've been using BCB's castor oil/DMSO blend in my left eye and plain castor oil drops in the right eye that had the surgery.

I did not have laser assisted surgery. I spoke with several ophthalmologists until I found one that did not insist I should have both eyes "done." (I've read various things about the importance of sunlight entering the eyes and really hope to keep my remaining natural lens...The docs I spoke with claim that the artificial lenses block all UV light...Is that a good thing???)

Anyway, I opted for the light adjustable lens in my right eye. It took a while to finish the subsequent light treatments because my eye was often too dry to perform the treatments, but eventually they were completed and I now have 20/20 vision in this eye.

I certainly wish you all the best with the decisions you will be making. Have you tried the N Acetyl L carnosine eye drops? I've heard some very good things about those as well. Perhaps using them with the DMSO???

In any case, good luck with everything!

Expand full comment
Soujourner's avatar

Have you been using this twice daily? My cataracts are just forming and according to my MD it's 'too soon' for surgery. Certainly, I agree! I'm going to give this a try and just ordered it! Do you mind sharing more details like how many drops/frequency. Any noticeable difference if you forget a day or two due to travel or whatnot. Thank you!

Patricia Beaupre's avatar

Yes, I try to use them 2-3 times a day but do sometimes forget and don’t notice any difference if I forget a dose. The improvement has been very gradual but over a period of four months is definitely noticeable. I usually just use 1-2 drops in each eye and keep the eyes closed for several minutes to let the drops absorb. Warning: they do burn a lot, but stop burning fairly quickly. I started with the 20% drops and noticed more improvement when I moved to the 40% drops. I’m going to try the 40% drops with vitamin C next time. Good luck, hope they work for you and you can avoid surgery. That’s what I am trying to do as I’m afraid of complications from the surgery. Everyone I know that has had cataract surgery has had some type of complication. The most notable has been a detached retina which happened to my late husband, my brother and also my step daughter. Thus my fear of the surgery…

Soujourner's avatar

Thank you for the response! I ordered the 40% with vitamin C so I'll keep you posted. I will try for a few months.

Best wishes for healing before surgery as a last resort. I appreciate your wisdom and advice. 🙏

Hopinow's avatar

where do you get 40% drops? or do you make your own with distilled water? Tnak you.

Patricia Beaupre's avatar

I order them from Amanda Vollmer’s store… DMSO.store.

Roman Stasiewicz's avatar

Why not add 40% DMSO to 60% of distilled water?? Am I missing something?

Hopinow's avatar

DMSO.Store. these are eye drops. i get the ones that have VitC in them

Louisa's avatar

I am also wondering about how to dilute DMSO myself. From what I have been able to read thus far, it appears to be a 1:1 ratio. So then it would be 40% DMSO and 60% distilled water. But what if you use DMSO gel instead of liquid. I presume you could weigh the proper percentages of each but wish I felt more confident about it. I guess I will just have to experiment.

Carol B's avatar

I went to the eye doctor in 2016. He told me, at 54, I had the start of cataract. Not ripe, I would know when it was time. Eye docs messed up my husband big time. He’s now legally blind in one eye, one eye limited vision. He can still drive. Thankful. But they are not going to work on my eye if I can help it. So, 8 years later I’m doing ok. Did not go back. My distance vision is very blurry in cataract eye, if there is a cataract. But it always has been. I can ready perfectly with that eye though. At close vision. Other eye is pretty good. I did wear glasses. Trying not to. Only need when reading small stuff at distance. Left eye adequate for distance. Right eye good for reading. I would like to try dmso for eyes. Waiting for doc’s article.

BH's avatar

I have made Vollmer's DMSO recipe for cataracts but have not had the nerve to start using it. This will encourage me to do so. Where do you find it with vitamin C? I am so excited to have found DMSO for many reasons.

Kathleen Cronberg's avatar

DMSO.store is where they are buying the eye drops, with or without vitamin C. I’m going to order these this week, I ve been looking for information on adding the C, Ute haven’t found anything so far.

Hopinow's avatar

i ude the one with VitC and it has worked fine/. They also say take a teaspoon of DMSO in orange juice or pomagrante juice.

Vidalia's avatar

Hi Patricia, I am wondering if the improvement in your vision has continued; and if you have continued using the DMSO eye drops for cataracts. If so, can you share with me the name of the product you are using? Have you researched the long-term safety of using the drops? I have moderately severe cataracts and am trying to avoid the surgery. Thanks in advance!

Mary's avatar

When I click on this link, I get a warning message that it has been reported as Malicious. Does anyone else get this? I have cataracts (not surgery-advanced) but also dry Macular Degeneration. I'm hesitant to try this in my eyes. I have been using DMSO gel for my varicose veins and have seen some improvement, but not a lot. I started using DMSO and castor oil on my Dupuytren contraction and see a slight improvement. Should I start with the 20% or go to the 40%? I see that you posted this several months ago, and I would like to know how your cataracts are now.

Old_Mainer's avatar

We need to apply DMSO over large areas. It is so much easier to apply it, cover with stretch kitchen wrap (We have stretch-tite.) and get dressed again. The wrap comes off easily later after the DMSO is absorbed by the skin.. Less mess and way less time.

This does increase the itching/tingling sensation slightly but it doesn't last long.

***CAUTION*** Put a piece of your wrap over a drinking glass, liberally apply your DMSO and observe after an hour. If there are no signs of discoloring, stretching or dissolving then your brand of wrap is good to go.

A Midwestern Doctor's avatar

Do not do that, it can pull the wrap's chemicals into the body.

Old_Mainer's avatar

Stretch-tite is BPA-free polyethylene. You cited polyethylene as safe for IV use with DMSO in Part 1.

My literature search suggests that PE is not good for long term storage as DMSO may seep through the wall over time.

Kathleen Cronberg's avatar

Can DMSO be applied to a hip and thigh area where I have a hip replacement and a rod screwed into my femur? My right knee is shot, it was in bad shape before the broken femur last year (after hip replacement), but after several months of having to keep my weight off the left leg, the right knee has given me a lot of grief). I applied DMSO mixed with a few drops of vitamin E oil to my right knee yesterday. Felt almost immediate relief. Applied it again before bed, and had a great night’s sleep, with only a little manageable pain when I woke up. So now I’d like to use it on my hip area and along my horrendous scar, which goes from just above knee to the middle of my butt) from 3 surgeries on broken femur and hip revision. But I’m concerned about the artificial hip and rod, will DMSO do damage to those?

Jade Dixon's avatar

I admit I haven't heard much about DMSO until now, but I have a relative who is in chronic pain from a back injury and also has end stage renal failure. So I'm wondering if DMSO is hard on the kidneys, like the ibuprofen my relative can no longer use. Haven't been able to figure that out one way or the other yet.

A Midwestern Doctor's avatar

It is not hard on the kidneys which is one of the many reasons why this is so egrigious.

Sam Miller's avatar

There have been stage 3 kidney failure reversal with a plant based low protein diet, look up the Kempner rice/fruit diet for kidney failure https://www.researchgate.net/publication/338142516_Plant-based_dietary_approach_to_stage_3_chronic_kidney_disease_with_hyperphosphataemia

See also this doctor that reversed her stage 4 kidney disease with raw vegan diet

See also https://pmc.ncbi.nlm.nih.gov/articles/PMC3586961/

yantra's avatar

MWD, the very skilled osteopath/MD i am seeing told me that DMSO can do some of the same damage to bodily tissue that steroids like cortisone do - for example that it can cause thinning of the tissue it is applied to. What do you think about this? i had just started to use it for musculo-skeletal issues so asked her about it.

A Midwestern Doctor's avatar

I have never heard of that happening and I wonder if it was due to steroids being used concurrently with DMSO.

yantra's avatar

She didn't say that but who knows. It is even possible ( i guess) that because she is both an MD and an osteopath, that perhaps she has drunken some of the AMA kool-aid. Anyway, i appreciate your answer.

Isaac Chambers's avatar

Question about traveling with DMSO.....

Is DMSO considered a hazardous substance for when you are flying? I would like to take the 70% solution with me....but unsure if i can?

A Midwestern Doctor's avatar

I do not believe so, but it is somewhat flammable

Darlene Lessing's avatar

You’ll have to have it in your checked in bag. Only if it is around 1 oz in your carry-on. Better to have a newly purchased product in your check-in.

Fred's avatar

Perhaps you have heard about the B1 therapy for Parkinson's disease ? There is a lively group on FB, started by Daphne Bryan, and apparently many experience substantially reduced symptoms. They use a sublingual form of B1, and recommend keeping it under the tongue for 20-30 minutes. Dissolving B1 in DMSO works fine and it absorbs great through the skin, quickly - I have tried it.

St. Mudphud's avatar

With the current context, how can someone who is interested in research get involved with projects exploring this or other forgotten therapies to further our understanding of these things? Is that even possible? What IRB would be ok with this being proposed? Does one have to work outside traditional academia?

A Midwestern Doctor's avatar

As best as I can tell, you have to have a smaller institution with its own IRB

Dan Star's avatar

Is it OK to mix DMSO and Methylene Blue in water?

Dan Star's avatar

Doc, any advice for a 5 year old Shepsky female dog who has genetic CCL problem resulting in a tear in each rear leg and surgery with titanium support? She is sometimes slow getting up. I would like to experiment with DMSO to give her more comfort. Thx!

A Midwestern Doctor's avatar

Good chance it could help.

Jason's avatar

Hello AMD, I am a new paid subscriber and reading your articles gets me excited to learn medical knowledge.Thank you forthoughful and well balanced articles. Your information makes me feel very confident to take my health into my own hands.

You mentioned a small part related to a potential allergic reaction in some individuals, that it happens in 1/2000 ppl. Is this just a hives and itching? Or is a fully blown analphaltic shock?I attempt to search for such thing but could not find that, but did find more of skin irritations. I am awaiting for my order from Jacobs labs to arrive.

If some one has a sulfa allergy, I had a horrible whole body rash to some sulfa antibiotics about 20 years ago, could they be more sensitive to DMSO? Thank you!

A Midwestern Doctor's avatar

More towards the hives end. There were a few case of mild laryngeal edema but everyone I read said they found the allergic reactions tended to not go towards the anaphalactic ends.

debu's avatar

After reading the first part of this series on DMSO I was eager to try using it on tendinitis in an elbow and meniscus-related pain in a knee. I did so topically at 70% dilution applied 2-3x daily for five days and it seemed to be helping but had to stop as my wife found the odor the DMSO caused me to emit (which I couldn't detect myself) so objectionable that I was banished to the sofa every night.

I would very much like to resume the DMSO treatment if would be possible to do so without smelling like someone who lives under a bridge. Is there any way of ameliorating this side effect?

yantra's avatar

i have recently tried the low odor 99+% pure DMSO, brand DMSOstore from amazon, It has very little smell upon opening the bottle and very little after use - as far as i can tell.

Garhett Rittenhouse's avatar

I use the same brand...I smell like hell. MWD mentioned its probably the oxidation of the cells or mitochondria or something???? He also said you can reduce (maybe eliminate the smell) using chlorine dioxine:

https://www.midwesterndoctor.com/p/dmso-could-save-millions-from-brain:

Note: one school of thought in integrative medicine (e.g., Dr. Mercola is a strong proponent of this model) argues that insufficient oxidation, which leads to a build-up of reduced molecules in the body (termed reductive stress) is a root cause of many illnesses (e.g., the mitochondria cannot function properly if the electron transport chain is reduced). The susceptibility to the DMSO odor is one of the best illustrations I have found of this model, particularly since there are many reports showing that concurrently taking chlorine dioxide (an oxidizing agent) eliminates it (as does a user’s overall health improving over time). Likewise, some DMSO users and one study have found that when DMSO was taken at the same time as alcohol (another oxidizing agent), the odor was reduced, whereas when alcohol was given an hour after DMSO, the opposite occurred (which touches upon the fact DMSO can sometimes cause excessive drowsiness if combined with a sedative).

Took me awhile to find it. I put the wrong chlorine in another comment...have to find that. Apparently, chlorine dioxine is a very useful thing as well. Might have to try it.

yantra's avatar

interesting - i have been reading about chlorine dioxide fairly recently (via Dr Yolo's ss) but honestly am a bit leery about all of these chemicals, tho the results with ClO2 sound amazing . . .

With dmso i am wondering if in addition to possibly restructuring our collagen (which i guess could be good or bad, depending . . .), i am primarily wary of it's solvent effects on things like glues used to cement dental crowns, and also its' potential to perhaps excavate poisons like mercury which have been sequestered in the body for decades, maybe dumping them in the bloodstream or whatever all of a sudden. I know someone this happened to who tried DMSA - they had had a lot of childhood mercury fillings (long since removed). The results were terrible. From that perspective, ClO2 sounds safer than DMSO, but really what do i know.

Garhett Rittenhouse's avatar

Maybe you could try the MSM? He referenced that too. I'm not sure it would help with your brows/skin tho'...

I think I might try to the chlorine dioxide. My smell is pretty strong so I have to do something.

A Midwestern Doctor's avatar

It is easily available online and I included amazon links for it along with Jacob's lab.

Fred's avatar

Should smokers take any particular precautions when using DMSO?

A Midwestern Doctor's avatar

Make sure nicotine or part of the ciggarrette is not on the area where DMSO is applied as that can get too high a dose into the blood stream.

Colleen's avatar

Just wanted to let you know how much I appreciate your articles; I am in awe and eagerly await the next installment. Thank you so very much for all of your hard work. Just ordered my DMSO and zeta aid!

Mark Devereaux's avatar

Two questions: (1) I had a total knee replacement last November that didn't turn out too well - flexion is only 80-90%. Could DMSO have enough on the scar tissue to allow for greater flexion? (2) I have peripheral artery disease. Could DMSO be used to alleviate that disorder?

A Midwestern Doctor's avatar

Yes to both although you may need other things too.

Mark Devereaux's avatar

I'd love to know what those other things are. Thanks!

A Midwestern Doctor's avatar

Various types of injections into the scars (ie. prolotherapy) or an appropriate manual therapy to loosen it up.

Mark Devereaux's avatar

I could ask a lot more questions, but please allow me one final one. How/where do I find someone who has the skill and knowledge to provide these injections and would be willing to do it?

J T's avatar

In a person with metal and partly ceramic/plastic knee and hip replacements, can DMSO be used to heal the joints, break up internal scar tissue, restore range of motion and stop the pain? Any safety guidelines to avoid absorbing the implanted materials into the body? Same concern with dental implants.

Thanks so much to you, MWDr, so grateful for my new subscription.!

A Midwestern Doctor's avatar

The short answer is that I have not come across any literature where this was assessed or any case reports about it. My guess is that there may be issues with direct applications to cobalt chromium ones (which leach regardless and cause a lot of issues) but not titanium. When it's put into another part of the body, its concentration is diluted enough by the time it reaches a prosthesis its unlikely to leach anything, whereas if it's directly applied to a prosthesis made from materials it could leach (which you'd need to look up), this may be an issue.

J T's avatar

After 3 joint replacements this year (metal and partly ceramic/plastic) I'm noticing an unpleasant intermittent feeling of insects crawling on my lower legs. I read this can happen as a reaction to a dental implant (which I don't have). I don't want it to get worse.

effga4trbfd's avatar

Hi Doctor,

Thanks for another great post. I'm eager to read the rest of the series.

A quick question if I may please - were there directions for treatment of gout? I saw it was mentioned in your article that it was effective but no treatment instructions/directions.

Thanks

A Midwestern Doctor's avatar

"Gout—DMSO (at 75-80%) tends to work better for acute than chronic gout (bringing rapid relief in those instances) but can also help with chronic cases."

This would be a topical application

effga4trbfd's avatar

Thank you - sorry if I was being dense, I did try to read the instructions! haha

Thanks again

shasta (non-English speaker)'s avatar

With what kind of water does one dilute DMSO before using?

Dan Star's avatar

Mountain Spring Water is no go?

shasta (non-English speaker)'s avatar

Not directly from the tap, then. Can one buy distiled water in the pharmacy and use it to dilute DMSO to the desired concentration? If DMSO allows everything to get into the body, it seems risky not to use the right diluent.

A Midwestern Doctor's avatar

I just use home purified water from a reverse osmosis water unit.

Karen's avatar

After reading your first series on DMSO I bought some hoping to help my sister who has lost her memory over the last 4 yrs...it seems to have gotten worse in the last month. I wanted to have her rub it on her forehead to see if that would help. But she read a book about it and said not to use if your on any medications. Well she takes Effexor for depression...do you agree?

Garhett Rittenhouse's avatar

For what's its worth (not medical advice), I drink orally and have three meds (methotrexate, leflunomide, and prednisone). He says in the series it can enhance the medicine. But, if she just starts with a very low dilution (20%) maybe she will find it helps...

Good luck.

Niall's avatar

Anybody care to recommend a European source?

Valda Redfern's avatar

I live in the UK and get mine from here: https://dmso-supplier.com/?syclid=ff692dd5-0542-4613-950a-c910c126d34b . I could just get DMSO from Amazon, ut they seem only to do small bottles, while the German supplier also offers bulk quantities (up to 25L), which work out much cheaper.

Niall's avatar

Thank you Valda. I purchased some from Amazon.de, a mixture with cream and a high purity liquid. Fingers crossed

Neil's avatar

What dose for strokes and oral or topical?

Mariann's avatar

Wonderful article. I wonder if DMSO could be used for chemotherapy-induced neuropathy (Padcev is drug)?

Vera Raia's avatar

Thank You sooo much for these DMSO posts, I love you for helping people. My question to you is can I apply a 50/50 DMSO to water or distilled water over a newly put in Pacemaker or around it? I have significant bruising to my armpit. Pain only if touched. I have ordered abdc received my bottle and am using on my knee and it is helping. This information has been life changing GOD BLESS YOU :)

Elaine's avatar

What is your opinion on mixing DMSO with castor oil. I got a 30% mixture from the person I do FSM treatments with. Unfortunately I reacted badly to it. She gave it to me to help with liver detox. I put some on. recently and did not have a reaction but it may have deteriorated because I kept it on an open shelve in a clear glass bottle.

A Midwestern Doctor's avatar

That is a very popular combination I was going to go into in a later article.

Kimry's avatar

Milk thistle is supposed to be good for liver detox

Elaine's avatar

I started taking a living detox with milk thistle the day I found my liver enzymes were over 1100. I think it saved my liver. The MD wanted me to take prednisone I never did. It took a Functional Medicine doctor 4 years later to find the mycotoxins that caused the liver problem.

Kimry's avatar

Great news. My functional medicine doctor just found my decades long GI problems were caused by fungal/yeast overgrowth. The herx reactions suck but I'm so glad I'm on the road to recovery.

Peter Denomy's avatar

Thank you for this info MWD,

Could you give an opinion on this DMSO product that is available here in Canada from Amazon. It appears to meet the criteria that you have presented in your article. My application would be for my back. I had L4-L5 disk removal and vertebrae fusion almost 7 years ago. My surgeon suspects internal scarring is exacerbating problems with the sciatic nerve. We don't want to go surgical again if we can help it.

Cheers.

https://www.amazon.ca/Platinum-Enhanced-MAXIMUM-Relief-Canada/dp/B0CJ11VNVX/ref=sr_1_4?crid=16DR2NW5YR6QU&dib=eyJ2IjoiMSJ9.hbt2C8jdqJCh7wX8m1LuZLEXj64erDOtxpEY6GFt9urGcjpa2gIHNwCshgaQlRydygaZJrgYaaiF71B-39I1ahbkH6WCLl5hpC6SKWg6Sp4UNbKeFvlV7KMRdcgIEwW8LNa4x7a9EeYErMqQkwLmmFMebQ3QaCrJr7FfLBddAOn0BN5pcCM6_gnPRChRVAaPxYG-7XQ0L-4HWYOcuuxOGgaBYHKX8yF37mzQOU1wrKZb1FT2BtzPkEB33XK_WxEX9PEHpq1DnUx9IvHe5AP1SUHp2dNM6M29D0okB2cHThc.NIWtpkXcwRF58-IF9Lse25c0mWmJMwKEZxyTOaZFKvg&dib_tag=se&keywords=dmso&qid=1727711455&sprefix=dmso%2Caps%2C179&sr=8-4

A Midwestern Doctor's avatar

Seems fine although:

High DMSO concentration so may have more skin reactions.

Is a gel so can't really dilute it

Peter Denomy's avatar

Thanks Doc. I'm going to give it a shot. Not much else is helping the almost constant aching.

Ruth Lock's avatar

Not sure if I can recommend these peeps but Canadian & good source for DMSO: https://realrawfood.com/products/supplements/dmso

I have NO connection to them, I just order from them regularly.

Peter Denomy's avatar

Thanks for this link Ruth. I'll keep them in mind.

erin's avatar

Very exciting, Doc. Many thanks!

Will you also write about oral uses? I haven't worked up to those yet.

My main use so far: for a 50 year old small scar from a deep burn on my wrist. The scar had begun to spread and there was some minor (but alarming) subcutaneous bleeding and I wanted to prevent future issues. Applied 70-80% for 10 days., a few times a day. This was in August. It itched a bit. Then took a break of a couple of weeks. Then did again in September. Now I am about to do it one more time. It has been fascinating to watch the skin healing, one little bit at a time. It truly does remodel the skin! The scar is now almost invisible, but still there in faded and diminished form. I expect the area to be completely healed with one more 10 day application.

Small Heberden's node on my index finger. It is diminished somewhat. My application for this was irregular, over the last two months.

Seborrheic keratosis (barnacles of aging): did not work. It may be it would take longer.

A Midwestern Doctor's avatar

Right now I have this at 5 or 6 parts.

•Everything the FDA did with it.

•DMSO for Cancer and Infections (a lot of this is quite amazing)

•DMSO for autoimmune disorders and collagen disorders and internal organ disease

•DMSO for head neck eyes ears and dental conditions (ie. macular degeneration).

•Applications of DMSO being combined with other substances (ie. my favorite one was using it to give people night vision, but there are a lot of other more commonly used ones like the castor oil example).

The other ones should be a bit easier to write though (except for the cancer and infectious diseases).

I'll probably space them out a bit more so everyone isn't just get flooded with DMSO.

erin's avatar

Fabulous. I am adding that at this point, I am eager to be flooded! :-)

I wish I had known about it for my frozen shoulder 7 years back. The phyz therapy worked, but it was excruciating, and left some residual damage.

sadie's avatar

I just relieved my 2nd bout of frozen shoulder with live saurkraut juice... not the cabbage but the juice.. 1/4 to 1/2 cup 2xs a day. Costco carries the organic raw stuff you need. Within 12 hrs pain was greatly reduced and continued to decrease.

erin's avatar

Internally or externally?

OneDayAtATime's avatar

Hi AMD. Thanks for another incredibly helpful article. In the part where you discuss DMSO for infections, I am curious if you will be discussing the use of DMSO for Covid, Covid vax injuries and long Covid. While I appreciate the likely lack of research in this area, given that DMSO improves mitochondrial function and reduces clotting, Covid seems like an important application for DMSO.

KARN's avatar

Equally curious about its application for these Covid conditions . Anybody out there with experience using DMSO to treat these kind of conditions - would love to hear about it .

OneDayAtATime's avatar

I have been using DMSO internally for long Covid fatigue for about 2 weeks. I started with 2ml of 99.9% DMSO diluted in about 8oz of reverse osmosis water. I learned pretty quickly that I need to pulse the dosing by taking it every other day and I also need to stay really well hydrated. Otherwise, the herxing is pretty intense.

I have noticed a substantial improvement in my energy levels and physical endurance during exercise as a result of this protocol.

Walt's avatar

Absolutely terrific articles .. really wish I had all of your articles many moons ago!!! A thought re this DMSO series .. perhaps publish the completed series as one PDF book available via Substack for a modest amount??? Personally, I would love to have a unified reference.

Nama Paula's avatar

You are amazing ! & put your talents to such good use! God bless you!!❤️🙏

sadie's avatar

How long did you apply to barnacles? And what strength?

erin's avatar

70%, and I did it for 10 days. The barnacle swelled up a little. May even have grown a tad.

So I quit.

They can be gotten rid of with strong peroxide, but they tend to come back. Some not for many years, though.

J T's avatar

Can DMSO heal tooth grinding? It's a lifelong problem that has been very destructive to my teeth.

A Midwestern Doctor's avatar

I have not come across anything on this one.

Darlene Lessing's avatar

You might want to try a good magnesium supplement if you are not already. Glycinate or Malate or magnesium chloride. Dr. Caroline S Dean is a magnesium expert and she finally made her own because she couldn’t get anyone to make it. Many Americans are magnesium deficient.

Miss Rodeo's avatar

We use Mercola’s threonate and have for years.

Katherine Quinn's avatar

Thank you for this very interesting article and for all the research you put into it. I thought I just posted a comment but it seemed to disappear on me, so forgive me if this is a repeat. I've had a tendon injury in my ankle for years and no matter how much I ice and rest it, the injury returns as soon as I get back on my peloton bike. I'm going to give DMSO gel a try. I have a question on a completely separate health-related subject. My 28-year old son was diagnosed with IgA Nephropathy in 2017. It's an autoimmune disease that causes the kidneys to get clogged and not function properly. There is no known cure, only diet and lifestyle related recommendations to slow the progression of the disease. The doctors have had him on statins and blood pressure medication for years and nothing has helped. Last year he started to have severe attacks of gout when he ate red meat and other food triggers, so he now has a very restrictive diet. Recently, I've been reading about some new drugs being approved that have been successful (in trials) at targeting the root causes. The other day, he went for his regular visit to the nephrologist and was told that he is to far along for any of the new drugs and that within 2 years he will need to be on dialysis, or get a kidney transplant. We are currently researching transplant centers, but in the meantime, I am always looking out for any information that is not in the mainstream. There seems to be a lot about kidney disease, but not as it relates to IgAN. Do you have any information or research on this subject?

Arabella's avatar

For topical application as a liquid or gel, are there any studies showing how deep into the body it is absorbed? Particularly interested in the pelvis bones. Thanks in advance.

Andrew's avatar

Are there any longitudinal studies that you've come across on DMSO?

It has so many methods of action that one might be tempted to use as a supplement; reduce oxidative stress, other toxins etc.

It seems to be very safe and well tolerated in the short term, but one wonders if chronic daily use might have untoward effects, this study suggests DMSO of 0.1% can change gene expression in human embryo cardiac models, but I don't have the knowledge to contextualise something so far from day to day life

https://www.nature.com/articles/s41598-019-40660-0

Andrew's avatar

just read your reply to Dr. Maria D Oliver which broadly covers this question, thanks

pridgway's avatar

Thank you so much for all you do! Question. Recent sports injury requiring surgical fixation of ulna using titanium plate and screws. Any issues of using DMSO in cases like this? Does DMSO react with titanium?

sadie's avatar

Had my radial done almost 2 yrs ago... the soft tissue and small fiber nerves will never be the same and I fight carpal tunnel... in my research I came across a discussion where a guy said he had put a titanium plate in dmso and then analyzed it after some time. Nothing was in it. I wish they had posted what he tested for because I assume the plate is an alloy so not sure if it was analyzed for everything.

Don Bishop's avatar

Has DMSO been used for the pain from broken ribs? (My wife broke 4 ribs last week.)

Brewer55's avatar

This post has me very interested as I am pushing 70 and have multiple areas of pain and soreness. Nothing really debilitating but, more of a nuisance. I eagerly await the 3rd post to find out your recommended source for DMSO.

edservice's avatar

Maybe you missed it in the article, but he referenced sources in the article. AMAZON

Penny H's avatar

As always, thank you so much for taking the time to provide this information to us. I hope you know how much you are appreciated!

Unfortunately, the products you suggested will not ship to commie Canada. It's not surprising but I will definitely keep looking. I'm interested to see if this could reverse some of the damage done to my muscles.

IdahoScot's avatar

Look at feed stores/farm&ranch stores. I'm only seeing 99% at those places here in the US, but it's easy enough to thin with distilled water.

Ruth Lock's avatar

Penny, there are many sources in Canada. A quick internet search is all you need to find it. Good Luck.

Penny H's avatar

Hi Ruth, I don’t know about many sources. I found one brand on Amazon (Naka) and another at Well.ca. The good news is that I have some on the way so we’ll see if it does what I hope it does! Thanks.

Meglet's avatar

Any research on using this during pregnancy? I've got a bottle sitting on my kitchen counter and would love to use it to alleviate back pain but I'm hesitating.

A Midwestern Doctor's avatar

There were a few animal studies that showed something potentially concerning that was never confirmed in humans. As a result, the DMSO fields perspective is "don't use while pregnant because the risk is still unknown." However, as far as I know after millions of people using it for 50 years, no pregnancy issues were discovered.

Baga's avatar

Remember the first rule of pregnancy is not to expose your baby to anything untested. You can unring the bell if your baby is harmed.

RU Pondering's avatar

Unless it is an untested (in pregnancy) gene therapy masquerading as a vaccine. In which case, we have it on good authority that it would be unsafe NOT to take it.

I’d add a sarcasm indicator, but my level of disdain for the FDA in this regard is well beyond sarcasm.

Meglet's avatar

Which is why this bottle is sitting on my kitchen counter unopened.

Valerie's avatar

I have read that putting castor oil on the skin prior to topical DMSO can help with skin irritation. Is this safe to do?

Lone Star's avatar

Is having had an all-titanium C-spine fusion a contraindication for DMSO use for pain surrounding the fused area and small fiber neuropathy? If not, how should it be used or applied?

Molly Aderholt's avatar

Thank you so much for this article! My son has been suffering about a year with what has been diagnosed as "athletic pubalgia" after an MRI. Essentially the MRI showed inflammation in the groin area right where adductor and abdominal muscles come together in the pubic region. He is a serious soccer player and even with physical therapy and time off, it is reoccurring, very painful, and negatively impacting his play. The doctor prescribed Voltarin which worked initially but no longer (and now I'm concerned about its toxicity). I have ordered DMSO per this article and will try that instead. I am wondering if there are any concerns for a male to use DMSO in that pubic region?

Carolyn Hurwitz's avatar

Thank you so much for this comprehensive explanation of the benefits of DMSO. Do you have more specific information on using DMSO for Down Syndrome patients? Or where I could find more in depth treatment guide for using DMSO for Down Syndrome?

HappyWife's avatar

Does anyone know if a roll-on version is reasonably safe on my 11 year old?

He has minor pain in his wrist / top of his hand.

Chris's avatar

I now have a question, I believe in your water series, you had mentioned Life Water has one of the best but i started to buy it and like it and realized they are using recycled plastic, isnt that something we should stay away from and get more no BPA bottles, like Essentia? thanks

A Midwestern Doctor's avatar

He is very confused and it's quite surprising to read it as this is basic pharmacology.

Over 90% of drugs are toxic to cells at 1%, and around 0.0001% is the typical threshold where you get mitochondrial damage. DMSO's toxicity is dramatically lower, but once you hit the 1% threshold, some studies show toxicity or changes, others do not.

When DMSO gets in the body, it rapidly dilutes to very small concentrations, so you never hit those high concentrations. If you covered your entire body in DMSO multiple times per day, it would not be possible to get the DMSO concentration in your body to 1%, whereas to do it orally, you'd need to drink close to a liter each day (and people rarely drink more than a few teaspoons).

Conversely, there is a lot of data that DMSO improves mitochondrial function and gives people energy.

alison's avatar

Thank you for your reply. After reading your explanation I will be more careful about what I take for granted what is reported in Orthomolecular Medicine.

A Midwestern Doctor's avatar

I am really baffled on this because I had a lot of respect for that group although I did not engage directly with them.

Jay Thomas's avatar

This is a great read. I found this one before part 1 so I haven't read it yet. I'm 67 and a former college tennis player. I have dealt with a lot of orthopedic over my time...broken arm, twice same femur at age 13, 3 rotator surgeries, perineal ankle repair, etc. I take care of my health in general but am having recent issues with arthritis in my L wrist/thumb area and now my knee. I love to play golf but am fighting through the arthritis now. I am looking forward to trying dmso. I turned down the offered cortisone shots. Is there a specific MSM or Chondroitin/MSM that you recommend in addition to DMSO?

Laurie's avatar

Someone I know sent this to me. Any ideas?

A little experience to relate about DMSO. I was unable to walk most of the past week after applying it to the back of my knees. They're improving now, but my right knee became swollen and painful when I had to work the joint. My knees are better now, but the aching has spread to the entirety of both legs. I am on advil and marijuana right now, just to cope with it and get some sleep. On the bright side, the edema in my shins, which persisted for at least five years, has all but disappeared. DMSO is powerful stuff, but not to be taken lightly!

Lloyd Chambers's avatar

My wife cannot stand the smell of DMSO, even the DMSO Store 99.995% pure stuff is quite smelly, contrary to claims. A day later, she and daughters complain that I stink.

Does MSM have equal or at least significantly similar therapeutic properties to DMSO?

...and is MSM truly zero odor?

James's avatar

Are there any medications that you need to be careful with if using DMSO? My father wants to try it for burning mouth but he is on a number of things including dexamethasone at the moment. I'm also not sure how he would use DMSO for burning mouth would you just rub a dilute solution on your mouth? Or make a mouthwash?

Ifeoma's avatar

Doc, have seen any study with DMSO and wheezing around the sinuses and ringing in the ear? The wheezing is so bad. I’d have what would be the dosage using 99.99% gel?

Maria Hunt's avatar

@midwesterndoctor Thanks for this super informative and well-researched post. I didn’t know about DMSO before finding your work and now I use it frequently in a little roller bottle mixed with organic castor oil, emu oil and lavender essential oil. It helps with scrapes, bites and soreness. But the most miraculous thing is how DMSO helped shrink my longstanding thyroid goiter. (I had been drinking a custom Chinese herbal goiter tea for about three years and saw no change.) I applied my DMSO mixture and then put on a castor oil neck wrap. After a week of wearing it overnight, I was shocked to realize the goiter had shrunk by half! I wanted to ask your thoughts on something: In my hula class, the teacher reminds us to smile while we dance. One of my hula sisters, a stroke survivor, commented that she can’t smile anymore because the muscles in the right side of her face droop. I was thinking of sharing DMSO with her. I know DMSO can help stroke survivors with brain recovery. Do know of any cases where applying it topically has helped restore the use of facial muscles post stroke? Thanks in advance.

John's avatar

Dear AMD,

This is an amazing list of potential applications for DMSO.

1. Have you read any articles or testimonies regarding potential use of DMSO for improving the ability of small intestine villi to receive nutrients in celiac or gluten sensitive individuals?

2. have you read any articles or testimonies regarding the potential use of DMSO to improve the ability to digest nutrients for individuals who are heterozygous and COMT for MTHFR?

Thank you for any information you can provide.

John

Susan G's avatar

Thanks for all the great comments! I had a hip replacement 2 1/2 years ago. Anyone know if it's ok to use DMSO on that area. I do still have some pain in the SI joint area and along my thigh (trocanter). Dr said it's fine on X-ray could be stenosis of the spine. I have read that DMSO is not good to use around metal. Any reports of experiences would be appreciated.

Debbie Wolff's avatar

How would I go about locating a doctor who would be willing to inject a/the knee with DMSO? My doctor will not; all he will inject is a steroid.

I am overweight and have bursitis in both knees, and osteoarthritis in the left knee. I've been using DMSO topically now for just over a month combined with either thyme or peppermint essential oil. I have periodic pain relief, which is great. I would like to have DMSO injected to see that would alleviate the pain permanently.

BeBe's avatar

Doctor, you’re an amazing human being for helping the masses like this! I have terrible trigger thumb and have had two steroid shots which haven’t worked. Any advice?

Barry Kivell's avatar

I have looked everywhere to try to find out how to mix DMSO 99.9% Pharm Grade with distilled water to use internally. I can find no information on the internet about how to mix it or how to take it or for how long to use it. Your articles are GREAT but at what ratio do you mix it for different health conditions? Is there a website or where can the information be found????I HAVE LOOKED EVERYWHERE, can anyone help me out????

A Midwestern Doctor's avatar

1 tsp in a glass of water.

Barry Kivell's avatar

Thank You, could you give insight? DMSO vs MSM (sodium chlorite/citric acid)? both seem to do miraculous things??? one better at treating certain conditions over the other?

Barry Kivell's avatar

I have looked everywhere to try to find out how to mix DMSO 99.9% Pharm Grade with distilled water to use internally. I can find no information on the internet about how to mix it or how to take it or for how long to use it. Your articles are GREAT but at what ratio do you mix it for different health conditions? Is there a website or where can the information be found????I HAVE LOOKED EVERYWHERE, can anyone help me out????

David Kamnitzer's avatar

For chronic piriformis syndrome .... would you recommend a combo of topical and IM injection, or ???

Lorita's avatar

As a new subscriber I wanted to thank you for the article on DMSO. After reading the article I feel more confident about the safety of DMSO. I am hoping for this treatment to help my 77 year old husband for what appears to be neuropathy that keeps him awake during the night because of tight leg muscles and pain. I was hesitant but now I think we should try it. We've tried other things, but some of those things have consequences that are not good.

Edward's avatar

Is it safe to use DMSO after having had knee and hip replacements? Can the DMSO cause the artificial joints to loosen? I had Juvenile Chronic Arthritis and have had several joint replacements and am trying it to manage pain and also for general health improvement. My cardiologist said I only have one coronary artery working, with a stent in. I made a mix of 50% DMSO (99% purity) liquid and 50% aloe vera gel which I am spreading on my feet and left knee and am concerned it might affect the integrity of the artificial joint. I also take two drops of the 99% DMSO in about 300ml of sparkling water once a day and am planning to increase to five drops eventually. I started about two weeks ago. I am a 64 years old male, weighing approximately 50kg, living in South Africa.

Any advice/recommendations would be greatly appreciated.

Ms Good's avatar

Where do I find dosing and sourcing information?

Noel's avatar

In one of your articles you mention that in order to treat psoriasis we can use camptotheca nuts in 70% dmso. Where can we buy this ointment or gel. Thanks

michael f hughes's avatar

I just dabbed a bit of DMSO on my eye lids and got an immediate improvement. I could see my pool shots so much better. I am cautiously continuing treatment.

Vic's avatar

Could you advise of a reliable source for DMSO in the United states, please. I would love to give it a try

Thank you for a comprehensive article !

Paula Williams's avatar

Fascinating! My gel should be here Saturday for a sprained knee. Can DMSO help with neuropathy? Five years ago I had an abscess in my spine ( no one could figure out why). Emergency laminectomy preformed. Ever since then I’ve had neuropathy from toes all the way to rib cage.

24/7 pain.

Melanie Kimball's avatar

Are there research citations for treatment of neuroma with DMSO? I've only found one and friend is desperate. Thank you

Doug Cragoe's avatar

After playing a lot of tennis I now have tennis elbow. I see on Amazon there are DMSO products with added ingredients. I'm wondering if I should use DMSO alone or try one of these products with added ingredients, as DMSO helps them get absorbed. I don't have a lot of pain, but I can't keep playing as much as I'd like or it could get worse. I want to recover as fast as possible. Any suggestions? I know I can do exercises and stretches for tennis elbow.

Katya's avatar

I've just spent way too much time talking to google ai only to find out it can not give me pictures and also it explaining that the "pulmonary arteries" are not connected to the skin so I can't get a good pic so I could understand where the heck this is, preferably from the front so I can put it in myself.

Sherry's avatar

I've noticed when I take DMSO orally that my skin drys out. I also tend to urinate more. I guess that's why my skin drys out. LOL.

Chasing Naomi's avatar

Wow. Enlightening. I had a very successful HTO on my left knee a 8 years ago. My right knee more recently was diagnosed (by two orthopedic surgeons) after MRIs with either a slight meniscus tear or osteoarthritis. Physiotherapy helped with the pain. But at my age, 74, while I can row and walk OK, I have pain, usually if I walk too far or in the evenings. I intend to give DMSO a try on both. I bought one of the recommended 70/30 liquids and will follow your directions. So we'll see. My question may be a strange one. I have two old small dogs: a 16.5-year-old Yorkie, and a 15-year-old mini poodle. The Yorkie has bad hips and the poodle a bad knee. If I were to try DMSO on them, how would I go about it? I live in Tokyo and I am sure my vet would want nothing to do with this. If I would be required to shave the affected areas, I would skip it--I don't want to traumatize them. Thanks for your time.

Chasing Naomi's avatar

The poodle's knee is small, about an inch in diameter. Could I just apply DMSO 70% liquid on the fur with a q-tip?

Gerry Bourlier's avatar

I find your information enthralling. I’m a retired peds NP. My husband is in his 2nd full year of monthly desensitization after an anaphylactic reaction from a hornet sting(required EMS,epi,ER observation). Labs at this point continue to show 50% sensitivity. Considering use of dmso for ongoing fungal toenail problem. Safe to use?

Na's avatar

Love your research and articles! My dog has hip dysplasia and arthritis. I’m putting dsmo in his water bowl but it’s not helping. Any other suggestions? Where is the best source of dsmo? The one I have is in a plastic bottle. Thank you!

KML's avatar

Is DMSO effective in treating DeQuervain's tenosynovitis and bone spurs? If so, what is the protocol?

Michael McDaniel's avatar

Where are the articles on using DMSO for specific conditions? I tire of reading "about" DMSO. I'm already convinced. All I care about at this point is how I can use it to treat my pain and other conditions.

Joyce Bulger's avatar

Not seeing how many times per day to apply topical, can anyone mention? I note the dosing and to take a break, like not on weekends, but not daily frequency.

Thomas F's avatar

Hi Doc. I’m sorry if this was previously covered in the comments (there are so many that it’s hard to peruse them all), but can you please describe how to apply dmso for tinnitus? Thanks-TF

Hiroya's avatar

Does anyone know a trusted source where I can buy DMSO + magnesium spray ?

Rosie O's avatar

Thank you for all this wonderful information!! Question: My husband has Parkinsons and wants to use DMSO for his arthritic knee. Is it safe to use DMSO with his Parkinsons medication and will it interfere with the effectiveness of the medications? I'd also like to know if there is a protocol for DMSO to treat Parkinsons. Thank you!

Patrice's avatar

I tested my AMD with an Amsler's chart earlier this year and my left eye showed distorted lines.

I've been using the DMSO 40% eye drops 2x/day since the first of March plus started drinking DMSO (5 ml in 16 oz of distilled water a day) in mid April. I tested my eyes this week with no distortions....YIPPEE!! Thank you for the info.

I wanted to let you know that I buy my DMSO from DMSO.Store in Canada. I have tried others and like theirs the best. I ordered more a few weeks ago and received the below message from UPS yesterday.

Please provide FDA information for clearance: dimethyl sulfoxide DMSO is considered a drug to the FDA, if this is over the counter for personal use, we will need a copy of your foreign passport to send to the FDA for clearance.

I certainly don't feel comfortable sharing my personal info with the FDA. Anyone else have this experience?

Jeff Bernat's avatar

Excellent article. Thank you MWD. Is there any research about using DMSO with pudendal neuralgia? As a teenager, my sister-in-law was in a very serious car accident (she was in a coma for weeks and her pelvis was crushed requiring surgery). She has been diagnosed with pudenal neuralgia some 25 years later - and experienced bouts of debilitating pain, with little relief from injections or any pain medicines. Any help would be appreciated.

Linda's avatar

I was chatting to a GP in Sydney and asked if they could inject DMSO for arthritis in the hip. The GP said a doctor must do a specific course required by the TGA to do that. I am wondering if anyone knows a GP who could do this in either Sydney or Melbourne, or how could we find out? Or should the person with arthritis just persist with applying DMSO liquid every day (which is already helping) and see how they are a year or two down the track?

Linda's avatar

Could you please clarify re applying DMSO liquid on the hip (for arthritis)? I understand the hip must be clean, but does it matter if elsewhere on the skin (i.e face) there is make-up or other creams (that is, does the WHOLE body have to be clean of all things, even though DMSO might be applied in only one area)? Many many thanks....

WatchinIt's avatar

I need a book - a PDR of DMSO - that lists conditions and treatment specifics (concentration, dose, frequency, etc). I’ve looked at the contents for several of the many books about DMSO on Amazon but failed to find what I was looking for. Has anyone found one?

Denise's avatar

In my excitement for the information herein offered, I ordered the following DMSO from Amazon not realizing it contains a warning not to use on skin. Is that simply a CYA type of warning or do I need to dilute? I’m looking to apply it on knees for pain from torn meniscus. Would mixing perhaps 50/50 with high quality organic castor oil do the job? Thank you for your response.

https://a.co/d/3KPV4vZ

sue's avatar

I like DMSO for many things but I still haven't figure out how to use it for back pain. Unless you have a practitioner who can inject/IV, it seems limited what you can do. I recently had a 6 week episode and tried DMSO topically a number of times and it didn't help at all. But I'm glad you're getting the word out and maybe someday there will be doctors trained in using this.

Kimberly Helms's avatar

If anyone knows of a doctor in Florida who uses DMSO please let me know via email. My daughter suffers from excruciating, debilitating pain and I will drive/fly wherever necessary in USA.

Kimberlyskreations@icloud.com

Craig's avatar

I have a rotator cuff tear (probably) in my left shoulder. I had the right shoulder rotator cuff surgically repaired and it's at 100?% My left shoulder got the same problem, then I tried laser treatment, that got it to 90% for about 3 years.

Then it started getting worse. I tried laser again, this time no luck. Also tried softwave at the chiropractor, no luck. I don't want to go through surgery again (took a year to recover).

Then it got MUCH worse simply by trying to remove a sprayer stuck on a hose: holding the hose with vice grips with my left hand and twist the sprayer UP with my right hand. Sudden pain, I could tell I injured it. Now it's probably 30%.

I bought Woldo Health 99.9% DMSO a few months ago, tried that, it irritated the skin a little but not much, but didn't seem to help. I wonder if this product is authentic.

Maybe I should try Jacob Lab? Maybe I need to spread it around a larger area - like maybe the back of the shoulder and down the arm a little instead of just directly on the shoulder?

I'd love to hear any ideas anyone has.

Nancy gutierrez's avatar

I know this is a difficult question to answer, but is DMSO safe to use when one has a partial or full titanium knee replacement? Hopefully there are some studies about this. I cannot find any info on this.

Paula Doucette's avatar

Hello thank you so much for all the valuable information you share that is unfortunately not available mainstream. I’m a seasoned RN and have studied and researched natural health/healing/therapeutic nutrition and I’m always so excited to add to this info to share with others. Where is a reputable source to buy DMSO?

Tammy Clark's avatar

I wanted to share my experience with DMSO for Restless Leg Syndrome. I have suffered with this condition along with insomnia for 30+ years. I was first prescribed a nightly cocktail of Clonazepam & Pramipexole. When that combo stopped working the Pram. was changed to Ropinirole then to Gabapentin then to a double dose of Gabapentin and then for the last several years Horizant (these were always w/the Clonazepam.) I still experienced RLS breakthrough even on the meds. I finally weaned myself off the Clonazepam but continued the Horizant. Wanting to get off the meds I incorporated Magnesium L Threonate orally & Magnesium spray on my feet & behind my knees. 3 months later still no relief. On April 23 I stopped the Horizant and started Non-Diluted DMSO Roll-On down both legs; sometimes spraying Magnesium on top. It's now been over a month. I have had 4 episodes lasting only about 15 min after going to bed. 2 were after a long airline flight and another that I equated to not exercising for 4 days (not sure if any of that is cause) I am no longer using the DMSO as it became really uncomfortable & I wondered if that was because it was no longer needed. I am ecstatic! I thought I would take these meds for the rest of my life. (ps. I am 64 yrs old)

I also developed a Cervical Dystonia around 25 years ago and take quarterly Botox injections. I have moved my next injections out a month and am now using the DMSO roll-on on the back of my neck 3-4 times daily. No progress yet but am hopeful!

Bayne Boyes's avatar

Hello Dr. Wilson, I am a subscriber doing deep dive research on both D-Hematoxylin and Ivermectin/Fenben (Dr. Makis) as my nephew has an advanced turbo cancer. Both protocols seem to have similar outcomes and so I am wondering what your view would be to take 'both' at the same time? Is it possible? R, Bayne Boyes, Canada

Chaim C's avatar

In turn, three “ideal” brands exist.

•Jacob Lab (e.g., this gel or this liquid)—which is 99.98% pure.

•Nature’s Gift (e.g., this gel or this liquid)—which is 99.9% pure.

•The DMSO store (e.g., this gel or this liquid)—which is 99.995% pure.

Has preference for source of DMSO changed?

Smrb69's avatar

A interesting side affect from using DMSO on my scalp for skin issues…..I used to get vertigo quite bad weekly but once I used DMSO I haven’t had a single bout. It’s been 6 months.

John Kerber's avatar

All the details about the great benefits of DMSO are valuable. What would really be helpful would be able to connect in central Iowa with someone who is capable to properly treat a friend with DMSO suffering from severe back pain from a fall. If an MD maybe, a nurse practitioner better.

Christine Johnson's avatar

My husband has medullary thyroid cancer and just recently (about a month ago) had an ethanol ablation on 2 tumors in his lymph nodes.

Unfortunately he had damage to the accessory nerve to his trapezius muscle. It is now paralyzed and we are waiting for I an appt with a neurosurgeon and neurologist.

Do you think this is something that could help with the regeneration of that nerve?

Ágnes Rumszauer's avatar

I would like to ask, if I use my hands for applying topical 90% DMSO for ankle sprain, how can I know the one time dosage? It seems to me very small amount of liquid which I can apply for one occasion. Thank you for your answer and I appologies for my bad English.

Dennis Lebbin MD's avatar

I've been using a 50% solution topically on severe right shoulder pain due to degenerative osteoarthritis. Improvement has been modest. What is the recommended oral dose in mgs & solution concentration for this type of pain ?

Nj's avatar

I purchased 99.9% pure DSMO liquid. Said was tested by 3rd party for purity. Want to use it topically for pain in spine, hips area. Have stenosis. Going to PT now. But not sure how to mix it? It's in a dark bottle with a dropper. Do I mix it in a glass bowl and apply to back, hips with cotton ball? (Can I put in plastic bottle with a sprayer?) Do I have to let it dry before putting clothes on there? Mix with distilled water? How much DSMO to water? Read 50/50 then read that maybe 70% DSMO works best. ?? (said to test on body first, so test the mix first or straight from the bottle?) Got it, but need advice to use it! Thanks for any advice!

Jules's avatar

Appreciate very much the detailed articles you've written on DMSO. I'm currently using is to relive chronic shoulder and neck pain. I was wondering if DMSO can be used on children? I have a young athlete (10yo) who is constantly spraining her knee/ankle or getting painful Charlie horses. I have read several books on DMSO, and the topic of children & DMSO isn't addressed much. Any insight is greatly appreciated. Tysm!

Christina's avatar

Thank you for all the information, You are a great help !!!

Ihave been using DMSO for my back pain and it helps me very much. It takes away all the pain. I would like to ask for your advice on the topic of my liver problem... Is it o.k. if I apply the DMSO on my liver area ?

Thank you very much !

Frank's avatar

I see that Amazon sells DMSO. But I have to learn how to dose it, etc.

Mrs. Itoldya!'s avatar

Now I have Hashimoto’s & a mass on my liver. Taking 12 mg Iver & 222 mg FenBen daily & applying just a bit of 70% DMSO daily on my sore ankle. I also have 70% liquid DMSO too. Would drinking 1/2 teaspoon of that daily, cause any negative interaction with synthetic hormone replacement medication?

Kimberly's avatar

I have the worst pain in my right SI joint and deep in my right butt cheek, a knife in the back of my right knee, and a lot of pain and prickles on the outside right calf. I think I hurt my back about 4 months ago and it's been up and down with pain. Right now, pain. Sometimes I can only walk and not sit or lay down. A couple times only I could lay down and not walk far without stopping for a pain break on my hands and knees. I've used 99.9% DMSO for at least a month topically off and on but it doesn't seem to help with my pain at all. I decided to add drops to my drink to see if that makes any difference. But so far my hip is unbearable even with DMSO. will drinking it help? So far I had 10 drops in goat milk. Still can't sleep from pain.

imelda jensen's avatar

Pat Don

SIL just used the DMSO roll- on, for a shoulder injury and got a severe skin reaction. What would be an effective first aid treatment be?

Pam's avatar

Dear ANYONE: All of the information is great but overwhelming! How do I use DMSO for chronic pain? Can someone please just tell me…..please…thank you

Andrea Stevens, M.S., C.N.S.'s avatar

From what I've picked up, start with a 70% gel and apply it with clean hands onto clean skin over the areas where you have the most pain. (By clean, he means no potential chemical residue from commercial soaps or lotions). Wait 20 min to let it dry and get absorbed before putting on clothing. There might be some tingling or skin irritation - if so, maybe just do once/day until that goes away. Otherwise, 2x/day seems like a good plan. The 70% DMSO gel (30% aloe vera) that is sold on Amazon from DMSO Store is a recommended and popular choice (it's the one that I purchased). He also recommends maybe taking 2 days off every week. If you don't find that very helpful after a month or so, you can consider getting the 99.9% pure liquid also from DMSO Store (glass bottle preferred for the liquid form) to take orally. Start with 1/2 tsp in purified water or organic fruit juice, once or twice/day. Go to 1 tsp 1-3x/d, if tolerated and helpful. Good luck!

Lynda Rae's avatar

I have burning mouth syndrome after surgery on my tongue for cancer. Would DMSO help this condition and if so, how would I apply or dose it?

Pedro's avatar

Regarding DMSO oral intake, any of those (Jacob’s, Nature or DMSO store) are adequate? after diluting it to reach desired concentration. Please help.

All of them say not for drug use

Andrea Stevens, M.S., C.N.S.'s avatar

Those are the brands that he recommends. The wording is just a disclaimer that is not meaningful for those of us using and recommending it.

Farming Chef's avatar

I’ve only bought DMSO where livestock supplies are sold us there another place that is better? I’m running low on 99%pure . Thank you for any help.

Jacci C's avatar

Working up a few formulations using DMSO at 50% concentration. For headache I'm using CBD, peppermint, magnesium sulfate, and lavender. For skin, I added aloe and tea tree oil. For muscle and joint pain, I added some castor oil. We'll see how this goes.

Co's avatar

There is so much confusion and money wasted in the area of skin care. I wish you’d take this area on .

Thinking Mama Bear's avatar

Great read. I purchased from health store 90% DMSO. What is the formula to get it down to 70% please❓

Also what strength, dosage and frequency for oral administration❓

What strength, dosage and frequency for placing in your EA❓

I have vertigo, tinnitus and I suspect psoriasis in my ear. This causes much itching, and bacteria due to fingers rummaging to get the itch.

David Moore's avatar

Did I see somewhere DMSO may have some benefits for ALS? If so, how can a doctor be found in North Texas area to work with this?

Thinking Mama Bear's avatar

It seems to me he is looking at DMSO from 2000 feet up from nonsensical FDA point of view. He is mainly pointing out it is not useful for covid. Whereas AMD is looking at it from 1-100 feet up.

TNad's avatar

I have 99% pure DMSO gel formula and distilled water. Do I mix this 50/50 and apply to area of pain. (spine/knees) The person I am helping (mom) is also a smoker. Seeing all these comments just makes me more confused. The article confused me on how to dilute. Thanks for any help.

scott carl's avatar

I don’t dilute the gel. Test applying it on a small area

TNad's avatar

Thanks for your response

We will try a small area first

Inge's avatar

Where can I find the treatment protocol with DMSO.

Very interesting study, thank you

erin's avatar

Doc, I just recommended DMSO for a neighbor with a knee swollen from arthritis. He, however, panicked, saying the internet says that it can speed up the heart rate and he is sensitive in that way. Have you heard of such a side effect from topical application?

Many thanks!

A Midwestern Doctor's avatar

At high IV doses it can slow the heart rate. Have not heard the opposite.

Michelle Goldstein, MSW's avatar

Considering trying this remedy for myself and other family members, who are struggling with various health issues mentioned in your articles and elsewhere. I don’t know anyone personally who has used it, but greatly appreciate you sharing this important information. Wishing you all the best!

Magpie's avatar

Given DMSO works well to improve neurologic genetic mutations such as Down's, has anyone looked at using it to help Huntington's? My niece's husband has Huntington's and all they do for him is basically watch and wait.

Sara's avatar

This is incredible. I have a very rare autoimmune that caused interstitial lung disease and it also attacks my muscles. How would I use DMSO for my lungs?

Christopher's avatar

There are so many comments here, but are there any recommended DMSO protocols? I tried for example using 50% DMSO on a spider vein on my foot, just as a trial, and within a couple weeks, the skin was scaly, and no change was visible to the vein. I'm sure it's something I wasn't doing correctly. I'm sure there's more to it than apply to the skin. Perhaps it's apply and then wipe off after X minutes, etc. Thanks for all the work you do!

AlphaZebra's avatar

What would be a good protocol for working with long time active Crohn's? Would DMSO be useful to imgedt and use as an enema? If do, what's recommended for dosage in enema?

Rod MacIlvaine's avatar

I am LOVING this series, and the robust engagement. Question: I have experienced chronic costachronditis for nearly thirty years. I tried a 70-30 solution with aloe vera; nevertheless, I am still experiencing skin irritation. Does the skin irritation lessen with more consistent use, or do I need to start with a milder dose.

TnDoc's avatar

MwD... Fantastic post! You never cease to amaze... Thank you for your voice!

Julie's avatar

Where in the world can I get some??? My husband has terrible and chronic disc pain from 2 car wrecks and our daughter has sacralization pain which has ended her career as a professional dancer. We really need help!

pimaCanyon's avatar

My first order was from Amazon, I got the red label 70% that MWD recommends and also the 99% from DMSO Store (even though I order from Amazon).

Just a few days ago I placed an order from the DMSO Store directly. I got it really fast, like a couple of days. I'd go with them. https://dmsostore.com/collections/liquid-dmso

Rammy's avatar

I got mine from the DMSO Store website, which also offers it on Amazon, and I had a good experience with them. MWD also lists Jacob Labs (and a third source I forget) which are also the best suppliers of pure-grade DMSO.

suzanne derham's avatar

My inflammation markers tend to be high. Is it good practice to take DMSO orally to reduce inflammation throughout the body. I thought I read 1 tsp. in juice twice a day, but I can't find the source.

Andrea Stevens, M.S., C.N.S.'s avatar

Maybe start with 1/2 tsp and increase to 1 tsp, 2x/day. The juice should be organic.

suzanne derham's avatar

My inflammation marker tends to be high. Is it good practice to take DMSO orally for overall inflammation in the body?

Desi's avatar

I’ve read a lot of the comments. I was just wondering if DMSO can be used for skin tags I have them all around my neck and under my breast and they’re painful at times. I just purchased from Jacobs lab 70% gel and 50% liquid DMSO. I’ve also purchased a subscription to AMD, and I am just so excited to be reading all the wonderful things that can be accomplished with DMSO. You’re an amazing doctor how horrible that you can’t be made known. You are definitely appreciated. Thank you for all you do.

LEA7's avatar

Having tried topical DMSO in pure aloe gel, I still had terrible itching and sensitivity, not the pain relief I was hoping for - did I do something wrong, or is there a better way? This is a non-surgical sprained knee and sleeping is difficult when pain hits inadvertently.

pimaCanyon's avatar

I would switch to the liquid. Try the 70%. If it still itches, go with a lower concentration. You can dilute the 70% with RO water or distilled water.

I have trouble with itching and burning too, and I've found the gel is the worst for that. The liquid can cause itching, but if I reduce the concentration, it's tolerable. The liquid dries in 10 minutes or so, and if there's any itching, it's completely gone when it's dry. The problem with the gel is it doesn't dry! or takes a very long time to dry.

I've used it for a knee problem and it's definitely helped!

LEA7's avatar

Yes! I’ve diluted 1:1 with aloe vera and it works well. I do rinse off after 20 minutes and will try to extend. Thank you!

Debbie T.'s avatar

Wonderful article! When applying with a natural fiber brush, would goat bristles work as well as horse hair? After using the brush, would I store it in a ziploc bag rather than rinse every time? Thank you.

Rosie Langridge's avatar

The point is to avoid using plastic fibres, so any animal bristle is good in that respect, but not the ziploc bag which is plastic.

Debbie T.'s avatar

Thanks--maybe I'll store the brush in a glass jar with a lid. Any recommendations for soft brushes is appreciated!

Rosie Langridge's avatar

I suggest you visit a shop selling art materials.

Debbie T.'s avatar

Actually, I just purchased a rollerball amber glass bottle and it works great!

Shirley D Evans's avatar

I have a friend from church that has an infectious sore/boil on the ball of his foot. He’s had multiple surgery’s trying to heal and close it and nothing has worked. This has been going on for months now. I’m perplexed as to what caused this to come up and he is too. Would DMSO help you think? Or would you have another suggestion? Thanks!

Rosie Langridge's avatar

Having read now a lot of A Midwestern Doctor's reports, I'm sure she'd encourage your friend to try DMSO. There's another report on using it for skin conditions and it clearly helps infections.

From my own experience, the cause of the boil could be a splinter in the foot or thorn or even an insect. I always encourage people to give their body the best chance to heal itself via basic lifestyle improvements to diet, outdoor exercise and stress reduction.

Michele's avatar

Hi, re: https://www.midwesterndoctor.com/p/dmso-is-a-miraculous-therapy-for/comment/71771426; Thank you for all you do to provide us with this valuable, detailed filled, life changing information! I copied a comment around Sciatica. I am hoping I didn't miss anything. I have a dear mom who has battled off and on with sciatica for years. This is giving me some hope. Does anyone else have experience with DMSO or another alternative for sciatica? I know the comment mentioned topical but wondering if that is good enough for sciatica or an injection is necessary...which can be problematic to find a provider willing to do? Any and all information around this would be so helpful! thank you ahead of time!

Second, how about for SIBO? I saw it briefly mentioned below. Did I miss that too? Thanks again!

A Midwestern Doctor's avatar

Most commonly siatica results from a tight piriformis. Putting DMSO over it can help, as can any other therapy or stretch to release the muscle.

Michele's avatar

Thanks for taking the time to respond, yes I was aware of the piriformis influence, sure she has tried therapy working on that area in the past. But willing to consider topical DMSO. Anything more on injections or SIBO? The positive outcome comment you shared in the article was from an injection but the doctor is now deceased unfortunately. Also, if I have success, I will definitely report back to share personal experiences.

Tasha Blank's avatar

Thank you so much for all your incredible work! I have a question about DMSO I haven't been able to find the answer to.

I'm considering using it for intense jaw and dental pain due to a series of dental reconstruction procedures. However, the reconstruction means there are materials in my mouth (porcelain, cement and temporary composite material) -- I'm concerned that even if I were to apply DMSO externally to my jaw, it might interact with / act as a solvent around the dental materials. Do you have any insights around this?

I also have the same question for my mom, who's recovering from a knee replacement. The replacement is made of titanium, so I wonder if the DMSO could interact with the titanium at all.

Would love to hear your thoughts on how DMSO might interact with any "non-factory parts" in the body.

Thank you!

AfD TikTok Account's avatar

Would you mind addressing the studies that claim to show DMSO is cytotoxic? I assume you will say the studies are flawed but would like to know.

Melinda's avatar

To reduce skin itching after topical DMSO application, I thought I'd share my homemade recipe with you all:

3/4 of a spray bottle of Thayers facial toner (alcohol-free formula witch hazel with aloe vera)

3 Tbsp liquid CoQ10 (I've only seen it sold at Costco in the US) - it gives your cells energy to heal

2 Tbsp micro-particle colloidal silver -mostly as a preservative

Optional: a few drops of liquid peptides for skin health and repair -they're long-chain amino acids; building blocks your skin can use to repair itself

I spray it on liberally and when it's dry, the itch has all gone for me! Bonus is that these ingredients also support your skin health and youthful appearance.

You can of course use it on it's own. I often do this before bed and wear a cheap silicone mask to keep the moisture from evaporating in my dry desert climate. And that's another reason the silver is added - to keep the moist skin from becoming a breeding ground for bacteria.

Side note: I also added a couple drops of mint essential oil and use black seed oil to dilute my topical solution of DMSO. The mint is also cooling on the skin and helps with pain relief, too.

eve's avatar

Any thoughts on mixing turmeric with a 50/50 DMSO solution? I'm asking for my 86 year old aunt with arthritis in the back of her neck. She has a hard time with turmeric capsules because the tiny amount of pepper upsets her stomach. Thank you for this amazing series!

pimaCanyon's avatar

you can get turmeric or curcumin without black pepper.

Have you tried DMSO without mixing with anything and has that helped the arthritis?

Leigh Ann Pitts's avatar

(I found your article Relationships at the Dinner Table Dec 2024 where you said we should comment so I am going to copy and paste it there also)

Hi Doc, much respect for all you do and continue to do! I just became a paid subscriber, SO worth it. I want to contribute to all you do. I can't even fathom how much time and effort it takes to compile the info you provide!!! I wish I could pay you to be my doctor.

I suffer from aggressive RA. I have combed through your DMSO articles but feel overwhelmed and not sure how to dose to try it or which type to use. I am trying many things to get off the drugs and to heal naturally. I don't want to trade RA for cancer because of methotrexate. I also stay sick more of the year then well and that's been the case since diagnosis and drugs. I am getting my last amalgams out in 2 weeks and then can finally detox. I have been to Panama to have golden stem cells that didn't do anything. Talking to a life coach to deal with trauma from a past abusive marriage and mommy issues. I want to do a nervous system reboot because I fear I am stuck in fight or flight. I am looking at ALL THE THINGS because that's what you do when you are desperate. At my worst, before I even knew what was wrong with me I didn't want to go on the rest of my life like that. It was extreme agony EVERYWHERE. I could not function or take care of my toddler, let alone myself not even able to dress, go the the bathroom , open a water bottle, shift in the bed, get myself ready or dressed at 43 years old. Then in March I got so sick with bronchitis I ended up in the ICU for 6 days with o2 dropped to 52 and left with an asthma diagnose. I am wondering if it's a result of the RA or the drugs for RA. Now I get super sick on the tale end of any mild runny nose sickness where I cough til I vomit and have to nebulize albuterol to ease troubled breathing. I refuse to let these diagnoses define me or control me. I just need to find the right doctors but I don't live in a good place for good healthcare options. the naturepath currently treating the RA is 5 hours away in Phoenix but I am willing to go beyond to get results beyond the ordinary.

I just gave up sugar but diet has been the hardest thing to change. I have not been able to get off steroids. My numbers were good so got off the methotrexate and was back to flaring in a month. I am on older mom to a 5 year old and desperately want to be healthy to live as long as I can for her. Any direction on fighting this is worth everything! Sometimes it's hard to know when people say "arthritis" which one they mean. I wish everyone would always be specific about that. When "arthritis" is mentioned which one is usually being spoken of? RA? THANK YOU!!!

vasanta's avatar

WOW, i just read one of your articles on DMSO and it looks like a dissertation! THANK YOU SO MUCH Dr! I'm new to your substack, in case my questions have been answered in previous posts. I have had high pitch tinnitus for over 4 years and it's only getting worse. I saw in your article that DMSO also treats it. Can you please elaborate on the doses and application. And if it's taken internally, how do you recommend ingesting it? Many many thanks in advance.

Robin Ray Green's avatar

I just want to thank you for all the work you do! The impact of your DMSO articles goes so far above and beyond. You've helped me and my family and I love supporting your work. I recommend your blog to friends and clients all the time. I love digging deep into the research and appreciate all the links.

Astrid Maria R's avatar

What is the protocol for taking DMSO orally? I see that you write it shouldn't be taken in higher concentration than 60% but I wonder is it best with or without food, and of course how much, etc. for severe osteoarthritis.

There are a few books on Amazon on protocols. Is there one that you'd recommend?

Thanks for any information.

Alex's avatar

Can you use DMSO as a smoker?

Kelly's avatar

HI Zade! Thank you SO much for your comments. How kind of you to take the time to respond. I am grieved that you too have been damaged by the fluorquinolone family. I am doing so much research and finding out stuff that none of my doctors seem to acknowledge or care about.

I will definitely share this info with the most recent naturopathic doctor I am seeing. There is a specialist in California that has had some success with reducing symptoms from FQ damage.

But I can't afford to get there. I am in Canada. I will pray that your symptoms continue to be relieved. Thank you again. Kelly

Not That “Karen”'s avatar

Hi AMD, I was wondering if you had run across this and what your response is to the information he presents. For those of us who are not scientists, it is very hard to navigate the often very contradictory information with which we are confronted.

https://open.substack.com/pub/geoffpain/p/dmso-gentoxicity-via-z-dna?r=3gip4t&utm_medium=ios

A Midwestern Doctor's avatar

DMSO has one of the best safety profiles of any drugs in existence provided it's used correctly.

I addressed most of the points he raised here and here:

https://www.midwesterndoctor.com/p/the-remarkable-history-and-safety

https://www.midwesterndoctor.com/p/the-fdas-war-against-dmso-and-america

Key points basically are:

He is very strongly biased against DMSO because he was told during his PhD training that it was extremely dangerous.

A significant portion of what he presented was not accurate.

Since the safety of DMSO is very high, he's had to look into fairly obscure areas to find potential issues with DMSO.

cmancini's avatar

Thank you for bringing DMSO to light. Super helpful for my trashed knee and rotator cuff injuries.

I know it amplifies supplements and prescriptions so what say you about spacing from Natural Dessicated Thyroid? If if take NDT at 7 am, then imbibe DMSO at 10 am, is there still a likely amplification effect? Or should I move NDT to late in the day?

Kelly's avatar

why is my comment not loading?

Kelly's avatar

There is Fluorouracil in this DSMO.....I was interested in it (DSMO) as a possible alternative to pharmaceutical antibiotics for infection and for chronic widespread neurological pain because of reading this article. However I can not use fluoride based drugs and after doing some on line 'research' discovered that this DSMO has a fluoride in it....which is a proven neurotoxin and is very dangerous for people with certain disorders. I was 'floxed' by fluoroquinolone antibiotics because I was given them despite having hypermobility syndrome. No one 'informed' me of the dangers. They ruined my life. So I am shocked that DSMO is being promoted so heavily on this site considering it has a flourine in it. If I am wrong then please feel free to correct me.

Zade's avatar

I bought 99% pure DMSO made in Japan, sold on Amazon. Pure DMSO should have nothing but carbon, oxygen, hydrogen and sulfur in it. I had a terrible reaction to Levaquin years ago so I avoid those meds too. I've tried this DMSO just this week and no bad reactions. No industrially produced substance is going to be totally free of impurities. But this stuff (Heiltropfen) seems to be pretty clean. And it's helped unbelievably well with the chronic nerve pain I've had for the past twenty-plus years.

Zade's avatar

Correction the Heiltropfen is 99.9% pure.

Toni Pecci's avatar

Thank you for such an informative article. I’ve been reading up on the use of DMSO (mostly from AMD) in regards to a few health issues I’m dealing with. One thing I haven’t seen addressed is how the use of DMSO, whether used internally or topically, affects prescription medication’s. Specifically, I am taking four prescriptions due to issues with long Covid/VAX injury. The medication’s are fluoxetine(Prozac), ivermectin, low-dose naltrexone, and sildenafil. do I need to discontinue any of these medication‘s before I can use DMSO topically for pain? I guess my main concern is the Prozac. I’m currently lowering the dose slowly however the last time I tried to get off it (back in September) many symptoms of my ailment began returning. Any advice would be greatly appreciated.

Odette's avatar

How many times a day would it need to be applied, say for hand joints?

Odette's avatar

Once diluted, how long will it store for? Also, what about using a red light after application? will this help it penetrate an area more specifically? Great information and much appreciated!

Yvonne's avatar

What sources currently exist for DMSO? Are there any current medical studies on the use of DMSO to treat joint pain due to cartilage degeneration?

Kaycee's avatar

Dear MW Doctor: Are doctors or Nurse Practitioners allowed to direct treatment of DMSO? Since the FDA banned it, how has anyone been able to get intravenous or other treatment that is not topical? I have been reading and re-reading all your articles on DMSO and perhaps am missing this info. Thank you.

James's avatar

Great article. Has anyone utilized oral/topical DMSO with Gout attacks? I’ve been using DMSO 70/30% gel with limited success on my big toe.

Anna's avatar

Unfortunately topical DMSO didn't help with my 2 year old granddaughter eczema. And it irritated her. I'm hoping that MWD will reply on my question in the other article regarding Zeta aid for toddlers...Thank you

Anna's avatar

I would like to add that let our experience not to discourage others to try. Because when I used DMSO for my smooshed between doors finger, it healed it miraculously fast. It was turning black and swollen in front of my eyes but after DMS swelling was gone overnight, nail was preserved, and completely healed in 3 days!

Marti Caskey's avatar

When you recommend MSM to be taken concurrently with DMSO for arthritis, is that an oral recommendation or topical? Thank you.

Kika's avatar

Apologies, off topic but I would like to ask our M.W. Doctor to consider writing an article about the deadly ingredients in most make-up. This would be especially useful for women.

This video is from my second favourite doctor, New Zealand's Dr. Sam.

https://drsambailey.substack.com/p/6-harmful-beauty-product-ingredients

Libby R's avatar

Has anyone used DMSO to treat a sacroiliac joint disorder?

Adele's avatar

I would like to know if it is safe and efficacious to use DMSO topically on a knee and the surrounding area that has undergone a total knee replacement? I am almost 18 months post-surgery and am still experiencing considerable tightness and stiffness, even though I have excellent range of motion. I also had iovera injections just prior to the surgery that I am wondering could have played a part in my unrelenting symptoms. My surgeon has no idea what is going on, and I have tried a number of different modalities, from frequency specific microcurrent treatments, to neuromuscular medical massage, different styles of physical therapy, rolfing, etc., etc., to no avail. Could DMSO help?

A Midwestern Doctor's avatar

Yes or neural therapy (lidocaine into the scars). Regarding the safety, we have not run into any issues with it, but it has never been comprehensively tested so I cannot say with certainty.

Adele's avatar

I have a follow up question that hopefully can be addressed. I forgot to mention in my post about my knee replacement that the surgeon had used cement to secure the implant. I finally got up the courage to apply it to my knee twice-- a 50% solution applied with an organic cotton ball to the back of my knee and the surrounding area. I didn't notice any change, but now, two days later, it is feeling different, more stiff and tighter than usual on the sides of the knee. I googled it and the AI summary said it should not be used on a knee replacement where cement was used due to the risks of negative effects on the implant and the surrounding tissues, that it could degrade the cement. Did I make a huge mistake?

Ben's avatar

What antifungal would you recommend using in combination with DMSO for toenail fungus?

My concern is that OTC antifungal creams might have toxins in them that you don’t want drawn through the skin.

Also, what do you think about the use of DMSO in children and even infants?

Benjamin Feeley's avatar

Hi,

I’m an acupuncturist and Chinese herbalist and am interested in experimenting with DMSO and Chinese herbal medicine. Have you come across any info regarding this? Any tips or advice?

Sincerely,

Benjamin Feeley

Sammie0627's avatar

I’m not getting any notifications when you post. I have to search to find your post. I am subscribed and can’t figure out why it’s so difficult to find your work. If there is anything you can do I really appreciate it.

A Midwestern Doctor's avatar

On my end, it says that you disabled emails. So you need to reactivate them (ie. by signing up with your email to this newsletter).

Sammie0627's avatar

Thanks I didn’t change my email setting but I’ll make sure I’m back on.

MtGrammy's avatar

Does anyone have experience with DMSO for treatment of flat wart-like skin growths? If so, what strength and how to apply?

A Midwestern Doctor's avatar

That is in the skin article.

MtGrammy's avatar

How should someone use DMSO to treat Tinnitis? What strength and is it diluted with only distilled water? Drops in ear?

A Midwestern Doctor's avatar

That is in the ears article.

MtGrammy's avatar

When diluting DMSO with Aloe Vera Gel Juice, the Aloe should be preservative-free, right? I can only find Aloe Vera with lemon or Orange added. What brand is good to use?

A Midwestern Doctor's avatar

Ideally, but it's also prosold as mixtures.

Rachel's avatar

I would really appreciate you weighing in on how to use DMSO (or anything else you recommend) for 1) post surgery pain due to a fractured bone and possibly also 2) a blood thinner to prevent clots. Secondary inquiries about how to help the bone rebuild best and how to flush meds from surgery out would be great to receive answers to also.

My brother was injured this week and had surgery at Vanderbilt for a bad ankle fracture, resulting in a plate and screws. He has a nerve block right now for pain but when it wears off in about 24 more hours or so he will very possibly be needing something for pain. He has prescriptions for oxycodone and gabapentin but would like to avoid having to take them if possible. A baby Aspirin twice a day was the recommendation for avoiding blood clots.

1. For pain (especially potential nerve pain), we currently have extra strength curcumin, inositol, and a homeopathic remedy for hypericum perforatum/aka St. John's Wort. But we also have access to DMSO both from KV Labs (99.99%) (https://kvlab.com/dmso-products/dmso-99-95-4-fl-oz) and also a roll on with Aloe Vera (99.99% DMSO) (70% DMSO, 30% Aloe Vera). Since his foot and leg are casted or wrapped basically up to the knee with a few toes showing, it isn't possible to apply the roll on directly where the bone fracture is. Would it be just as effective to apply above the knee or in the navel? Or would it be better to take the liquid internally and how much? 20 drops in 1/2 cup of water seems to be a potential internal amount I've seen that others have taken. I don't really know for sure though and would really like someone knowledgeable to weigh in on this.

2. For blood thinner or to avoid clots (to avoid taking two aspirin every day if he doesn't have to) he is taking at least 2 nattokinase per day, extra strength curcumin (doing double duty there), vitamin E, gingko biloba, but also realize DMSO is able to help thin blood or reduce clots. Wondering about the MMS/Chlorine Dioxide possibly with this although it could interfere with the other supplements potentially unless spaced out. I realize MMS and DMSO work together sometimes, though. (Any thoughts on that?)

3. For bone healing he is taking silica and Dr. Christopher's bone and tissue and also drinking 8 oz. of celery juice a day.

4. Any suggestions to help flush out meds used for anesthesia, pain, etc. at hospital?

I just became a paid subscriber (even if temporarily) to be able to see more about dosing and or how to use DMSO in this real life situation and read about commenting to gain more information. I do hope you can take a little time to help if possible. I will say my brother opted out of pain meds while they popped/adjusted his bone back in place manually before surgery and tolerated it well. He said the pain level was about a 6 on a 1-10 scale. They said most people were screaming by then WITH PAIN MEDS, so I'm hoping he won't have excruciating pain to deal with. We want to be prepared and wise though, as it is likely most people would have tremendous pain with a fracture and surgery.

Thank you for any help!

Expand full comment
A Midwestern Doctor's avatar

1) You can apply DMSO as they can tolerate and just need to figure out what that is. You can spray it on or lightly brush it on if they can tolerate.

2) DMSO and neprinol AFD (which contains natto) are the best natural anticoagulants I know of (along with zeta aid).

3) Homeopathic symphytum and biost often helps.

4) Subcutaneous B1 and B12 injections.

Rachel's avatar

Thank you! Am I right when I assume you prefer topical over internal consumption of DMSO? And how long is okay to leave it on the skin topically? Is the navel a good spot if you can't get to the foot or would you try to get nearer an artery above the wrapped part? Does it need to be washed off or just leave it on and don't worry about that as long as no clothing is touching it for at least 20 minutes or so to avoid induction of anything?

KT-SunWillShineAgain's avatar

THANK YOU ! If you can't wait for Amazon to deliver, and you're near San francisco, you can find it 8oz and 16oz in the supplements section its locked up at the Rainbow 🌈 coop on duboce and folsom. Also helps with foot circulation and flaky skin issues on bottom of foot.

A thousand 🙌. 😀

BlueHorse's avatar

Great article, but how do you use it?

A Midwestern Doctor's avatar

Is in the last part of the article.

LauraD's avatar

I am so grateful for doctors (like you) who are so willing to share your medical knowledge with the public so that we can take responsibility for our health. God bless you!

BRobi's avatar

Has anyone used DMSO for varicose veins? I mean the large, painful, bulging-like-a-python-digesting-a-rodent type veins?

I am assuming the dosing would be 70% solution or less, probably a gel or roller, but are there guidelines on how to start treatment? Small area? One vein? One leg? All at once? This runs in the ladies in my family and it sounds like this is the best solution ever, but I'd like to read further and advise properly.

Thank you, MWD, for your diligence, integrity, and courage.

Lyle Roland's avatar

I have a question. You did not discuss any oral treatment protocols in this fascinating article. My husband had a stroke in 2019. He was also diabetic. He had Perthes disease when he was a kid and spent 3 months in the hospital with his legs in traction. He has been in pain most of his life. He's done a great job exercising and getting off insulin using a book written by a dr. He keeps his blood sugar in check pretty well, most of the time. Where should I go for advice? Or is there another article you can refer me to? Thanks so much for what you are doing.

Tom Maloney's avatar

I was very interested in trying DMSO on my arthritic knees until I read this: https://www.nature.com/articles/s41598-019-40660-0.pdf. And this: https://www.nature.com/articles/s41598-022-07706-2.pdf And this:

https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fj.13-235440

I am not able to interpret these studies as to their impact on my health. Would appreciate any help.

Selma Terzioglu's avatar

Thanks to many courageous men and women like you, who created the path for the good, compassion, truth and remedies for the social, psychological, physical ills, induced on us by design.

The contrast between some of the billionaires who chose or agreed to destroy millions of lives in every possible way and the conviction of the individuals who risked everything they had, is described eloquently in the article below.

The anonymous hero of the pandemic: the story of the unknown doctor

He had to fight two enemies simultaneously: COVID-19 and the media.

https://filiperafaeli.substack.com/p/the-anonymous-hero-of-the-pandemic

FILIPE RAFAELI

Penny McLoughlin's avatar

I noticed for the first time reading this that you mentioned DMSO breaks down into MSM. I had heard that MSM use could increase the eye pressures in people with glaucoma but I'm assuming that DMSO does not have this issue?

Lucinda O’Donohoe's avatar

Thank you so much for all this information on DMSO.

I have a enlarged thyroid with goitres. I have sub clinical hyperthyroidism and take PTU medication. Would it be safe to use DMSO on my thyroid area to see if it helps reduce the inflammation?

Lisa Beth W.'s avatar

Does anyone have recommendations for what implements to use for dosing DMSO? I just have regular syringes and medicine cups made of plastic that I am very suspicious of, especially since the DMSO that I recently received is carefully packaged in glass and I've read about not storing it in plastic.

Linda Atchley's avatar

Is there a place on your Substack where there is info on how to use DMSO, liquid and gel, oral and topical, for various conditions?

Linda Atchley's avatar

Where can I go to find out how to actually use a 99% pure liquid DMSO? I love all the info on where it works, but no info on how to use it! Help!!!

OnceProudCanadianDave's avatar

I have started using DMSO and I’m experiencing the one side effect mentioned here which is the odour. AMD mentions taking chlorine dioxide along with DMSO to eliminate this side effect. Does anyone have dosing recommendations for the chlorine dioxide? And maybe a source of good quality safe product?

Judy's avatar

Thank you for your diligent work in offering a plethora of practical and encouraging information! I was referred to your site by a friend after recently purchasing DMSO.

I wanted to educate myself. I have learned so much already by reading your posts.

How would I go about finding someone to administer DMSO via IV or injection in my area?

Thank you.

~Judy

Judy's avatar

I am new to your site and am overwhelmed by the plethora of encouraging information.

After recently purchasing DMSO liquid, I was referred to your site by a friend so I could educate myself before using it. Thank you for the time you have invested and continue to invest in these critical matters.

How can I find a practitioner for IM or IV administration if needed in the future? Thank you for any suggestions.

~Judy

Glenn's avatar

I noted this morning receiving an email recommending Steve Kirsch's blog.. beware of wolves in sheep's clothing. Why? He made the mistake of getting on the wrong side of Anthony Colpo (also on Substack)

Kirsch offered a $25,000 challenge, Colpo completed it and claimed the prize.. Kirsch didn't pay up... big mistake, Colpo exposed Kirsch in a big way..

If anyone has knowledge of Colpo, he can be brash, but he is honest and very, very, very thorough.

Chester Gregory Laskowski's avatar

I have taken DMSO and it has helped for a tendonitis I had, Knee pain I was experiencing and lower urinary tract symptoms I was having but my family stated that the body odor that resulted was intolerable for them. I did not realize that I had this odor but it worsened the longer I used the DMSO. I did stop, and the odor resolved. What can be done to mitigate the odor.

Chester Gregory Laskowski's avatar

What do you do about the body odor that people get when on DMSO? I have been taking it and it has helped with my joint pain and prostate, but people around me are repulsed by the body odor that I have been producing since starting DMSO.

Toby Lee Shoemaker's avatar

I want to give a gift subscription of The Midwestern Doctor. How do I do this?

Eppure si muove's avatar

I read through all of the comments to see if the question had been asked/answered, so my apologies if it is repetitive. My pup, the sweetest 5 yo French bulldog you'd ever meet, had a slipped disc (breed notorious for IVDD) and has been taking Gabapentin and Prednisone the last week. After finishing the scripts, was thinking about DMSO on his spine; especially considering the anti-calcification effects from the DMSO (I recall reading this in one of MWD's epic posts). Anyone know of a vet who could tele-consult? Not sure of the best way to apply and dose.

Any suggestions appreciated.

Sandy's avatar

Has anyone had success treating pilonidal cysts with DMSO? Or the wound from surgical removal? My son has had 3 surgeries for that in 5 years. And heading towards another one if it doesn't heal soon. I assume apply topically around the wound but not on the wound? Any other ideas?

Staci Owen's avatar

Do you have any information on whether DMSO might help with hereditary multiple osteochondroma? My ten year grandson has this and has tumors on all of his growth plates.

The interesting fact here is that neither his mother or father have it and it’s supposed to only be passed down that way. We are curious that it could have been a childhood vaccine transference of some sort and given the junk they have found to be in some of these shots.

Yolanda's avatar

Is there any help for pudendal nerve damage?

Jeremy Shaft's avatar

Does redness with topical use = allergic reaction? I have used it a few times and I do get red, but it resolves after 20 minutes.

David's avatar

This question, I'm sure has been answered, but I do not know where to find the information on this substack, so I will ask it here.

If you dilute DMSO with distilled water, does it matter that the distilled water came out of a plastic bottle? I have not been able to find distilled water in glass bottles so far. Any insight would be helpful. I'm sure this has been asked and answered before, I just don't know where to find it, so I'm asking here. Thank you for being patient and understanding.

DR's avatar

Thanks for the valuable information. Would the DMSO be able to pull in metals from the mouth If taken orally? Such as mercury fillings which I have. If someone has metal plates in their body, hip, leg, arm, etc., would DMSO still be an option typically or orally?

Laura's avatar

Is DMSO know to lower blood pressure? It seems to be bringing mine down lower than my nephrologist likes.

A Midwestern Doctor's avatar

When given intravenously it does so temporarily, but I do not know about the situation you are describing.

Laura's avatar

I was putting 70% DMSO-30% aloe vera in a roll-on on one knee and quite a few varicose veins, plus on some bumps on my face I’ve had over 10 years. It’s probably quite a bit of DMSO. I do believe it has lowered my BP—I’ve stayed in the good range with fewer doses of one of my meds. The bumps are becoming smaller, and it improves my arthritic knee. Can’t see any change in veins, but it’s only been 3 or 4 days. It’s also great on a stiff, sore neck from driving for hours.

I really appreciate your sharing all this practical information.

Mary Anne Simpson's avatar

I bought my DMSO. I bought a gel and the liquid. I have been taking 1 tsp in a glass of water in the morning. I have vein issues and bladder issues that i would love to see if it helped with. Here is my issue: It makes me stink. And it’s so bizarre. My daughter smelled it emanating from my body the first day I took it. People at work smelled broccoli or cabbage smells and wondered what it was. When I walk in the door they smell me. Interestingly my husband cannot smell it. But many people and all young people can smell it. I don’t know if anyone has any advice for me. I’d love to stick with this and see if it helps me, but the smell part is just not something I think I can tolerate. Any advice?

A Midwestern Doctor's avatar

That is a common side effect, will discuss more about it in a later article

Mary Anne Simpson's avatar

Interesting that my superficial broken veins that were on my ankles and calves almost completely disappeared, however when I went off they came back. Do you need to stay on it or can it be a more permanent fix if you stay on it longer?

Garhett Rittenhouse's avatar

Dang, scanned all comments on there. Anyone have issues with what seems to petechiae (like broken blood vessels?) on your toes with DMSO? I didn't see this as a side effect in any of the MWD articles. Just wondering if anyone else experienced...could be the UVI but my last treatment was a month ago and didn't have it.

And, bad news: while DMSO helped for weeks tamp down my Inflammatory polyarthritis (which I think is just a more exciting name for RA which moves all over my body)...just the other note my wrists/hands (both of them) flared so bad, I was forced to jump back up to 20mg/day of prednisone. Bummer! Back to the drawing board.

A Midwestern Doctor's avatar

I would use a much lower does than what you are currently doing.

Garhett Rittenhouse's avatar

Thanks Doc! Yeah…I slacked off the DMSO. Unfortunately, back on a high dose of prednisone to offset the inflammation (which flared even with the DMSO 🤔😔). But, per ur guidance, I’m asking around to find a DMSO doc in the area. Wish me luck 👍🤣

And…as always…thank you for what you do (and for the personal guidance, in this case). 🙏

A Midwestern Doctor's avatar

People who are fixated on things tend to stay fixated on things.

My best guess is that he did his PhD training in the middle of the governments campaign against DMSO and at that time, to justify their abhorrent conduct, they tried to raise a hysteria about DMSO being as dangerous as possible (to the point you needed to treat it like hazardous waste that needed to be avoided under all costs in the lab which Pain wrote somewhere)...and because of that he's very strongly anchored to the belief.

I thought about it for a long time, and I can't think of any other pharmaceutical which has as low a toxicity as DMSO (and I would genuinely love to know if there is a contender).

In the case of birth defects with DMSO, there were a few animal studies that suggested high doses could cause issues in certain animal species but not others (like the eye lens issue) but this was never shown to happen in humans. The FDA had a razor focus on finding anything wrong with DMSO (e.g., they spent years going on about a single death from DMSO which could not be attributed to the drug) and as far as I know, they've never identified a single birth defect (overt or subtle) linked to DMSO despite millions of people taking it.

I also read through all the FAERS reports as I was researching this series (which he cited as a reason for DMSO being bad) and what they essentially showed was that DMSO was very safe and most of the (very small number) of reports were not of concern (e.g., a lot of them were complaints about the odor) or attributable to one of the other drugs the person was taking (as DMSO was just included in their list of meds but not cited as the suspected drug).

In the case of the DNA alternation, most compounds will affect DNA, but DMSO is unique in this manner as it was shown to stabilize proteins and DNA and protect them from damage rather than causing it.

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11 déc. 2024
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A Midwestern Doctor's avatar

Apply topically to areas that hurt with procotocols described here. Some find oral is better, or in severe cases IV

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28 oct. 2024
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A Midwestern Doctor's avatar

That is in the other article (on autoimmune and contractures)

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30 sept. 2024
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A Midwestern Doctor's avatar

If someone else wants to do that and donate the proceeds to a good charity I will support it, but I do not want to sell merchandise (same reason I don't promote my own supplements)

Glynda's avatar

AMD if I wash/dry my skin and apply DMSO, from what I have read the process into the body requires 20 minutes. So say half hour later I want to prep a raw chicken to roast will the residue from the chicken still enter the body? If so how long would I need to wait before handling it to be safe??

A Midwestern Doctor's avatar

Should be fine at that point but you can wash hands with water too first.

Glynda's avatar

You are truly amazing, I really didn't think, stretched as thin as you are I would get a reply. Deeply grateful for you bringing these forgotten tools back to us. The world is a better place, Namaste.

A Midwestern Doctor's avatar

I like to help but am stretched thing. It just really depends on when I receive the comment!